Nude mice
Effects of curcumin on growth of human cervical cancer xenograft in nude mice and underlying mechanism
... in nude mice and underlying mechanism. The nude mice modeled with human cervical cancer HeLa cell xenograft were treated with normal saline (control), 3 mg/kg Cisplatin, 50, 100 and 200 mg/kg ...
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Inhibitory effect of Dendrobium officinale polysaccharide on human gastric cancer cell xenografts in nude mice
... the tumor inhibition rate of in high-dose DOPA group was basically equivalent to 5-Fu group. Compared with 5-Fu, DOPA had no obvious toxic side effect on spleen or thymus indexes, routine blood indexes or liver and ...
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Inhibitory effect of Dendrobium officinale polysaccharide on human gastric cancer cell xenografts in nude mice
... DDPA can inhibit the growth of SGC-7901 cell xenografts in nude mice. The possible mechanism may be that, DDPA can up-regulate the serum TNF-α and IL-2 levels. In addition, the inhibitory effects may be ...
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High concentrations of L-ascorbic acid specifically inhibit the growth of human leukemic cells via downregulation of HIF-1α transcription.
... membrane matrix (BD Biosciences), and the mixture was transplanted subcutaneously into the right flank of 8-week-old nude mice. On day 8 after transplantation, the tumor volume was measured, and the ...
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Study of tissue inflammatory response in different mice strains infected by dematiaceous fungi Fonsecaea pedrosoi
... and Nude-r mice when compared to Nude (Figure 2B) and SCID ...and Nude-r ...munocompetent mice (BALB/c and C57BL/6) and Nude-r mice. In Nude mice, neutrophil ...
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Effect of melatonin on tumor growth and angiogenesis in xenograft model of breast cancer
... [53] nude mice bearing ER-positive breast cancer (MCF-7) (inoculated directly into the inguinal mammary fat pad of the mouse) treated with melatonin also showed smaller tumor size compared to control ...
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Monitoring pancreatic carcinogenesis by the molecular imaging of cathepsin E in vivo using confocal laser endomicroscopy.
... The monitoring of pancreatic ductal adenocarcinoma (PDAC) in high-risk populations is essential. Cathepsin E (CTSE) is specifically and highly expressed in PDAC and pancreatic intraepithelial neoplasias (PanINs), and its ...
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Visualizing the prostate gland by MR imaging in young and old mice.
... The prostates of 6 young and 6 old Nude mice and of 6 young and 6 old SCID mice were examined microscopically. After euthanasia, the animals were necropsied and the prostate glands were collected ...
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Neem leaf glycoprotein prophylaxis transduces immune dependent stop signal for tumor angiogenic switch within tumor microenvironment.
... treated mice having prominent ...from mice with NLGP therapy again restores both anti-angiogenic and tumor growth restricting effects of ...athymic nude mice and here also NLGP prophylaxis was ...
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Detection of Talaromyces marneffei from Fresh Tissue of an Inhalational Murine Pulmonary Model Using Nested PCR.
... Penicilliosis marneffei, often consecutive to the aspiration of Talaromyces marneffei (Peni- cillium marneffei), continues to be one of the significant causes of morbidity and mortality in immunocompromised patients in ...
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The Antitumor Activity of the Novel Compound Jesridonin on Human Esophageal Carcinoma Cells.
... Jesridonin, a small molecule obtained through the structural modification of Oridonin, has extensive antitumor activity. In this study, we evaluated both its in vitro activity in the cancer cell line EC109 and its in ...
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Repeated Gene Transfection Impairs the Engraftment of Transplanted Porcine Neonatal Pancreatic Cells
... To test if high glucose toxicity hampered survival of pancre- atic cells in the diabetes mouse models, we transplanted the transfected cells into normal nude mice. he pancreatic cells were unable to ...
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Characterization of a novel anti-cancer compound for astrocytomas.
... athymic nude mice (strain 088 or 490, Charles River Laboratories, Wilmington, MA) according to the NIH drug development program’s acute toxicity procedure with minor ...female mice (1–2 month old) ...
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C/EBPα Short-Activating RNA Suppresses Metastasis of Hepatocellular Carcinoma through Inhibiting EGFR/β-Catenin Signaling Mediated EMT.
... in nude mice. In vivo imaging of the mice over 40 days revealed that the size of the tumor (fluorescence intensity) and intrahepatic metastasis in C/EBPα-saRNA- dendrimer-treated mice were ...
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Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.
... 2/2 mice, which lack T, B and NK responses, are superior to nude mice for studies on human tumors ...2/2 mice in a few weeks, and gave also rise to ascitic fluid in most cases; this enabled us ...
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Improved local and systemic anti-tumor efficacy for irreversible electroporation in immunocompetent versus immunodeficient mice.
... (ID) nude mice, including the potential for a systemic protective effect against ...treated mice from each strain, and 7 controls from each ...IC mice relative to the treated ID mice ...
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The relevance of testing the efficacy of anti-angiogenesis treatments on cells derived from primary tumors: a new method for the personalized treatment of renal cell carcinoma.
... The capacity of the drugs to reduce or stabilize tumor growth was tested on subcutaneous xenografts of TFE3 RCC cells in nude mice. The tumor growth was rather long (three months), a result compatible with ...
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Evaluation of an anti-carcinoembryonic monoclonal antibody suitable for immunoscintigraphy
... American Type Culture Collection (ATCC; Rockville, MD, USA). The human mela- noma MeWo was kindly provided by Dr. Lloyd Old (Ludwig Institute for Cancer Re- search, New York, USA). LS-174T and HT- 29 were cultivated in ...
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