obese mice
Mitochondrial and metabolic dysfunction in renal convoluted tubules of obese mice: protective role of melatonin.
... lean mice without treatment (lean); b) lean mice treated with melatonin for 8 weeks (lean+mel); c) obese mice without treatment (ob/ob); d) obese mice treated with melatonin for ...
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COH-SR4 reduces body weight, improves glycemic control and prevents hepatic steatosis in high fat diet-induced obese mice.
... (HFD)-induced obese C57BL/J6 mice were ...HFD mice for 6 weeks significantly reduced body weight, prevented hyperlipidemia and improved glycemic control without affecting food ...HFD obese ...
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The obesity and fatty liver are reduced by plant-derived Pediococcus pentosaceus LP28 in high fat diet-induced obese mice.
... To elucidate the mechanism that combats obesity by LP28, we screened altered expressions of genes participating in lipid metabolism and biosynthesis. The expression level of CD36, which functions as a transporter for ...
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Increased Airway Reactivity and Hyperinsulinemia in Obese Mice Are Linked by ERK Signaling in Brain Stem Cholinergic Neurons
... An emerging line of clinical and epidemiological investigation has proposed a positive correlation between hyperinsulinemia and asthma independent of the body mass index (Arshi et al., 2010; Husemoen et al., 2008; ...
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The triterpenoid alpha, betaamyrin prevents the impaired aortic vascular reactivity in highfat dietinduced obese mice
... study, mice fed a HFD for 15 weeks showed increased body weights and abdominal fat mass, hyperglycemia, hyperinsulinemia, and hyperlipidemia, characterizing an insu- lin resistance and obesity state that was ...
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Altered Glucose Homeostasis and Hepatic Function in Obese Mice Deficient for Both Kinin Receptor Genes
... obB1B2KO mice showed increased blood glucose ...3-month-old mice, which was corroborated by elevated serum C-peptide ...in obese mice, suggesting a protective role of the KKS regarding ...
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Pregnancy in obese mice protects selectively against visceral adiposity and is associated with increased adipocyte estrogen signalling.
... HF-fed mice exhibited a remarkable normalization of visceral but not peripheral adiposity, with a 53% reduction in non-pregnant visceral fat mass expressed as a proportion of body weight ...between obese ...
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Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice.
... DIO mice indicates that the body mass was preferentially lost from ...fed obese mice (Figures 2A and ...Boc5-treated mice appeared to be smaller in size than that from vehicle-treated ...
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White tea (Camellia sinensis) extract reduces oxidative stress and triacylglycerols in obese mice
... White tea is an unfermented tea made from young shoots of Camellia sinensis protected from sunlight to avoid polyphenol degradation. Although its levels of catechins are higher than those of green tea (derived from the ...
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Preventive Effects of Chitosan Coacervate Whey Protein on Body Composition and Immunometabolic Aspect in Obese Mice
... Swiss mice twelve-week-old from CEDEME (Centro de Desenvolvimento de Modelos Experimentais da Universidade Federal de S˜ao Paulo) were housed ive in a cage in a standard experimental animal laboratory and kept ...
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Macadamia Oil Supplementation Attenuates Inflammation and Adipocyte Hypertrophy in Obese Mice
... Composition. Mice fed high-fat diet showed increased body weight gain, hypercholesterolemia, and insu- lin ...of mice fed high-fat diet (HF and HF + MO) was greater than in animals that received ...
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Preservation of metabolic flexibility in skeletal muscle by a combined use of n-3 PUFA and rosiglitazone in dietary obese mice.
... in mice fed an obesogenic high-fat diet that a combined use of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) and thiazolidinediones (TZDs), anti-diabetic drugs, preserved metabolic health and ...
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Human monoclonal antibodies against glucagon receptor improve glucose homeostasis by suppression of hepatic glucose output in diet-induced obese mice.
... insulinopenic status [5] or impaired counter-regulatory response of glucagon to hypoglycemia [6]. These inappropriate balances between postabsorptive and fasting glucagon secretion drive excessive HGP in T2D. However, ...
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Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice.
... We next investigated effects of palmitate priming on cells. Palmitate induced phosphorylation of p65 and p38 as early as 15 min and ERK at 45 min after treatment. 6 h pretreatment Toll-like receptor-4 (TLR4) inhibitor, ...
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Obesity impairs lymphatic fluid transport and dendritic cell migration to lymph nodes.
... K14-VEGF-R3-Ig mice [28]. These mice express a soluble VEGF-R3 antibody in the skin and, as a result, have severely hypoplastic dermal lymphatic vessels and decreased lymphatic ...and obese ...
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γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα.
... this, obese mice compared to lean mice have fewer skin cd T cells number and the few cd T cells they have are dysfunctional [73], which leads to impairment in wound ...in obese mice are ...
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Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice
... of obese compared with lean mice, as detected in basal conditions (PBS groups) and after OVA ...of obese mice to the levels of lean ...on obese asthmatic mice may be at least ...
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Obesity triggers enhanced MDSC accumulation in murine renal tumors via elevated local production of CCL2.
... tumor-bearing mice have not been thoroughly ...tumor-free, obese mice ac- cumulate cells with an MDSC phenotype, although the suppressive capacity of these cells was not examined [19], and a second ...
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Attenuation of the cardiovascular and metabolic complications of obesity in CD14 knockout mice
... genetically obese mice as well as in mouse models of diet-induced obesity (Lin et ...of obese WT mice, while TLR2 mRNA levels were elevated in the liver and subcutaneous ...of obese WT ...
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