Phase I
Estimating Multiple Step Shifts in a Gaussian Process Mean with an Application to Phase I Control Chart Analysis
... estimations are two units or less far from the real shift. As expected, the estimated probabilities of confidence intervals increase, for most of the time, as the size of change point increases. Besides, the method can ...
5
Clinical, ethical and financial implications of incidental imaging findings: experience from a phase I trial in healthy elderly volunteers.
... a Phase I IMP study were found to have IF on baseline MRI scans; a proportion that is twice that previously estimated ...into Phase I IMP studies, to fully appreciate age-related variations in ...
7
Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials.
... Global clinical laboratory work performed under harmonized operations is a central component for the successful conduct of phase I–III clinical trials in multiple fields of science and medicine. However, ...
5
Internship report on Blueclinical phase I unit
... aspects I noticed an improvement on was my organizational and time management ...months I felt the need to improve this aspect in order to better organize my time and, ten months later I can say ...
61
Clinical research on new drugs (Phase I). Profile of scientific publications: data from the pre-clinical phase and bioethical aspects
... phases. Phase I: a new chemical or biological drug is, for the first time, administered to human ...beings. Phase II: aims to study the therapeutic efficiency, dose range, kinetics and ...selected. ...
5
Phase I clinical trial of fibronectin CH296-stimulated T cell therapy in patients with advanced cancer.
... this phase I clinical trial, the frequencies of both CD27+CD45RA+ and CD28+CD45RA+ cells increased signifi- cantly after culture and their population in transferred cells were about ...
9
A pilot randomized, placebo controlled, double blind phase I trial of the novel SIRT1 activator SRT2104 in elderly volunteers.
... a phase I, single-center, double-blind, randomized, placebo-controlled, parallel-arm study to assess the safety, tolerability, pharmacokinetic and initial pharmacodynamic prop- erties of SRT2104 (Sirtris ...
16
Curricular training at a phase I clinical trials unit
... visit I had the chance to see a different TMF organization, other templates, and essentially I discovered a reality completely different from Phase I clinical ...In Phase I ...
65
Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer.
... a phase I trial of intravenous ascorbate added to gemcitabine and erlotinib in patients with stage IV metastatic pancreatic ductal adenocarcino- ma with the specific primary aim of assessing safety and the ...
7
Two-Stage Priming of Allogeneic Natural Killer Cells for the Treatment of Patients with Acute Myeloid Leukemia: A Phase I Trial.
... class I antigens [5] which may inhibit autologous NK cell function, attention has focussed on use of HLA-mismatched NK cells from haploidentical donors [6, 7, 8, ...
19
Stord Orographic Precipitation Experiment (STOPEX): an overview of phase I
... The measurements of STOPEX I cover the time period be- tween 24 September and 16 November 2005. During the campaign, 21 different precipitation events have been iden- tified with respect to the large scale ...
7
Improvement of the energy resolution via an optimized digital signal processing in GERDA Phase I
... Gerda Phase I where the preamplifiers had to be placed at a distance of 30–60 cm from the crystals due to the low background ...Gerda Phase I ...
12
Observations and implications of liquid–liquid phase separation at high relative humidities in secondary organic material produced by <i>α</i>-pinene ozonolysis without inorganic salts
... The presence of a miscibility gap at RH > 95 % has conse- quences for the CCN activity of particles as suggested pre- viously (Petters et al., 2006). Shown in panel a of Fig. 5 are simulated Köhler curves for SOM ...
11
CEVAP journal towards a new phase
... Sciences I, Nursing, Engineering III and Interdisciplinary; B2: Biodiversity, Food Science, Veterinary Medicine, Engineering II and IV; B3: Medicine I, II and III, Odontology, Public Health, Pharmacy and ...
2
Phase equilibria modeling for biofuels production
... For alcohols two association schemes can be applied, the 2B and the 3B. Kontogeorgis et al. [74-75] had shown that there is not much improvement in using the more rigorous (3B) over the simpler (2B) association scheme. ...
195
Phase quantification in nanobainite via magnetic measurements and Xray diffraction art hfgabreu phase
... of the ferritic phase (cubic or tetragonal) that can be incorporated to Eq. (4) by a constant k, which has a value of 1.052 for this study if the linear regression is performed with an intercept of zero. By ...
6
CMOS Phase Modulator for Polar Transmitters
... a phase modulator for a polar transmitter in (com- plementary metal-oxide-semiconductor (CMOS) 180nm ...a phase interpolator, a phase signal divider and a sign ...the phase interpolator, which ...
75
SPME, Solid Phase Micro-Extration.
... (compostos orgânicos voláteis) em água a SPME direta foi a melhor opção pois, com fibra PDMS 100 µ m as relações entre as quantidades recuperadas por extração direta e de headspace fora[r] ...
8
Phase Unwrapping via Graph Cuts
... The main contribution of the paper is an energy mini- mization framework for phase unwrapping, where the min- imization is carried out by a sequence of max-flow/min- cut calculations. The objective functions ...
13
Phase Behaviour of Alternative Solvents
... Song et al. [25] examined the use of typical all atom Lennard–Jones 12-6 plus Coulomb potential functions for sim- ulating the interactions between perfluorinated molecules and alkanes together with the Lorentz–Berthelot ...
149