Structure-activity relationship
Quantitative structure-activity relationship of some 1-benzylbenzimidazole derivatives as antifungal agents
... Quantitative structure-activity relationship (QSAR) has been used to study the relationships between the antifungal activity and lipophilicity parameter, logP, calculated by using CS C[r] ...
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Calculation of Quantitative Structure-Activity Relationship Descriptors of Artemisinin Derivatives
... Artemisinin and its derivatives are only the group of compounds that is still effective against drug- resistant P. falciparum strains, and has the ability to quickly reduce parasite level (Krishna, 2004). From the other ...
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2,3-Diarylxanthones as strong scavengers of reactive oxygen and nitrogen species: A structure–activity relationship study
... ing activity as it is evident by the results of compounds ...about structure–activity relationship of flavonoids and phenolic ...absorbing activity of ...
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Unbalance Quantitative Structure Activity Relationship Problem Reduction in Drug Design
... Quantitative Structure Activity Relationship (QSAR) models, which overcome the disadvantage of high cost and long cycle by employing traditional experimental ...positive activity is rather ...
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Quantitative Structure Activity Relationship and Risk Analysis of Some Pesticides in the Goat milk
... Quantitative structure activity relationship (QSAR) models were suggested to predict the residues of unknown pesticides in the goat milk using their known ...
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Design of Novel N-Myristoyltransferase Inhibitors of Leishmania donovani Using Four-Dimensional Quantitative Structure-Activity Relationship Analysis
... N-Myristoylation protein is catalyzed by N-myristoyltransferase (NMT), an essential target in Leishmania donovani, the causative agent of kala-azar. Four-dimensional quantitative structure- activity ...
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Quantum chemical properties used in structure-activity relationship studies.
... Este trabalho teve como objetivo demonstrar a variedade dos tipos de descritores moleculares baseados em cálculos químico-quânticos deriva- dos das funções de onda e distribuição de car[r] ...
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Evaluation of cytotoxic activity of synthetic bis-indolyl methanes: structure-activity relationship
... During the last years, the cellular origin of Hodgkin Lymphomas has been clarified. Due to the silencing of regulators of B cell differentiation (ABF-1, ID2 and NOTCH1, for example) or the disruption of B-cell specific ...
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Anti-Parasite and Cytotoxic Activities of Chloro and Bromo L-Tyrosine Derivatives
... a structure-activity relationship between the halogenations patterns in the aromatic ring of the L-tyrosine and the substitution of the amino group, looking for the best structural parameters for the ...
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J. Braz. Chem. Soc. vol.24 número1
... possible structure-activity relationship and allowed to establish some important features for the chalcones to be ...best activity against ...the structure of chalcones that may ...
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The effect of Cratylia floribunda lectin on renal hemodynamics and ion transport
... the structure-activity relationship among Diocleinae lectins, the direct renal effects promoted by the seed lectin of Cratylia loribunda in isolated perfused kidneys and mesenteric bed of rats were ...
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Braz. J. Pharm. Sci. vol.49 número1
... the structure can result in qualitative as well as quantitative changes in activity, which prompted us to undertake the synthesis of various 2-phenitidine deriva- tives and to study their ...
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Phenolic Acids and Derivatives: Studies on the Relationship among Structure, Radical Scavenging Activity, and Physicochemical Parameters†
... scavenging activity, although other mechanisms may be ...antiradical activity of phenolic compounds depends on their molecular structure, that is, on the availability of phenolic hydrogens and on the ...
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JISTEM J.Inf.Syst. Technol. Manag. vol.14 número1
... The relevance of studies into IT Governance mechanisms is evident in the international academic scenario. This is apparent in the various researchers who have dedicated themselves to studying these arrangements and ...
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prod 27 spe e20162207
... The relationship is planned to last the duration of each mentee’s university career which is currently four years for undergraduate studies (almost six years for those who enrol in the Master’s ...
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Novel chromone and xanthone derivatives: Synthesis and ROSRNS scavenging activities
... scavenging activity of phenolic compounds, delaying or preventing lipid peroxidation [21,30]. All of compounds achieved similar ORAC values which were apparently superior to the value presented by the ...
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Analysis of epistemic practices in reports of higher education students groups in carrying out the inquiry-based activity of immunology
... proposed activity, by reaching the correct answer to the set of experimental data that the groups were intended to solve the problem situation, prays stem cell, prays cells in the pre-B stage or prays to the fully ...
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Relationship Between Bilirubin Level and Disease Activity in Crohns Disease
... CD diagnosis was made based on endoscopic and histopatho- logic criteria. Clinical activity was determined using the Crohn’s Disease Activity Index (CDAI). It was deined as the active phase of the disease ...
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Mechanism for determining the ecology-economic activity of cluster structure
... enterprises activity within the cluster structure prompted the concept of «level of environmental and economic activity ...economic activity cluster refers to the degree of investment ...
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