Transforming growth factor beta
Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta.
... active transforming growth factor beta (TGFb), tumor necrosis factor alpha (TNFa), epidermal growth factor (EGF), and reactive oxygen species (ROS), as well as in response ...
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Dietary transforming growth factor-beta 2 (TGF-β2) supplementation reduces methotrexate-induced intestinal mucosal injury in a rat.
... decrease in mucosal DNA and protein, and decrease in villus height and crypt depth support this conclusion. Parallel decreases in mucosal DNA and protein indicate that the smaller mucosal mass of MTX animals can be ...
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Transforming growth factor beta receptor II polymorphisms are associated with Kawasaki disease
... Transforming growth factor beta (TGF-β ) receptor 2 ( TGFBR2) gene is a putative tumor suppressor gene that has been implicated in several malignancies 8) ...
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Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma.
... AEs considered possibly related to study treatment and occurring in .2 patients or reported as CTCAE $grade 3 are shown in Table 2. Observed AEs included gingival bleeding (4 patients), epistaxis (4 patients), headache ...
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Involvement of Transforming Growth Factor Beta-1 (TGFβ1) Cytokine and FOXP3 Transcription Factor Genetic Polymorphisms in Hematological Malignancies
... Considering the importance of tumor microenvironment permissivity and anti-tumor immune responses in cancer development, investigations were carried out whether TGFB1 rs1800470 (C29T; Pro10Leu) and/or FOXP3 rs2232365 ...
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Healing effect of andiroba-based emulsion in cutaneous wound healing via modulation of inflammation and transforming growth factor beta 3
... Methods: The wounds were harvested on days 3, 7, 15, and 20 post-surgery. Wound contraction rate, quantitative immunohistochemistry [macrophages, myofibroblasts, capillaries, collagens (col) I and III, ...
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Transforming growth factor beta 2 and heme oxygenase 1 genes are risk factors for the cerebral malaria syndrome in Angolan children.
... The Heme oxygenase-1 activity has been shown to suppress ECM in mice [47] and one report in Myanmarese patients suggested that short alleles of a GT repeat in the HMOX1 promotor region are a risk factor for ...
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Transforming Growth Factor-β: An Indirect Inducer of Th17 Cell Differentiation both in Human and Murine System
... Chabaud, M., F. Fossiez, J.L. Taupin and P. Miossec, 1998. Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 ...
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Arq. Gastroenterol. vol.49 número3
... Liu J, Liu CH, Hu YY, Xu LM, Liu P. Ingredients of Huangqi decoction slow biliary ibrosis progression by inhibiting the activation of the transforming growth factor-beta signaling pathway. BMC ...
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PDF PT Jornal Brasileiro de Pneumologia 11 9 portugues
... necrosis factor-alpha (TNF-α, fator de necrose tumoral-alfa), interleucina-10 (IL-10) e transforming growth factor-beta (TGF-β, fator transformador de crescimento-beta), pelo ...
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Rev. Col. Bras. Cir. vol.44 número4
... T he better understanding of the tissue healing process has led to new directions. One of them is to interpret it through the immunology, which investigates the intrinsic tissue and biochemical reactions in the repair of ...
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Avaliação dos marcadores TGF-β1 e TGF-βII em carcinomas mamários localmente avançados e sua associação com fatores clínico-patológicos
... Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas.. Goldhirsch A, Wood WC, Coates[r] ...
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Braz. oral res. vol.25 número2
... of transforming growth factor beta (TGF- β), interleukin (IL)-8 and IL-10 by human cultured periodontal ligament and gingival ibro- blasts both obtained from the same donors challenged with ...
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Identification of Novel Variants in LTBP2 and PXDN Using Whole-Exome Sequencing in Developmental and Congenital Glaucoma.
... WES identified potentially causative novel mutations in the latent transforming growth factor beta binding protein 2 ( LTBP2 ) gene in two PCG families. Gly1166Arg) was identified in the[r] ...
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TGF-β1 on induced osteogenic differentiation of human dermal fibroblast
... of transforming growth factor beta 1 to the osteogenic culture medium increased the activity of alkaline phosphatase and the amount of osteocalcin, but TGF-β1 did not alter the presence of ...
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Citocinas e proteínas de fase aguda do soro como marcadores de regressão da resposta inflamatória ao tratamento da tuberculose pulmonar.
... necrosis factor-alpha (TNF-α, fator de necrose tumoral-alfa), interleucina-10 (IL-10) e transforming growth factor-beta (TGF-β, fator transformador de crescimento-beta), pelo ...
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Citocinas e proteínas de fase aguda do soro como marcadores de regressão da resposta inflamatória ao tratamento da tuberculose pulmonar
... and transforming growth factor-beta (TGF-beta) in supernatant of peripheral blood mononuclear cells and peripheral blood monocyte cultures, without stimulus, of controls (n = 20), at ...
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Perturbation of EGF-induced MAP kinase activation by TGF-ß1
... (1993). Transforming growth factor beta 1-induced delay of cell cycle progression and it s associat ion w it h grow th-related gene expression in mouse ...
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Bioinformatics Analyses of the Role of Vascular Endothelial Growth Factor in Patients with Non-Small Cell Lung Cancer.
... initiating factor of VEGF signaling pathway. In addition, in the epidermal growth factor receptor (EGFR), VEGFA and VEGFB associated sub-network, kinase insert domain receptor (KDR), fibronectin 1 ...
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Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats.
... Fig 4. Changes in tubulointerstitial injuries related to aristolochic acid (AA) treatment modulated by anti- transforming growth factor beta (TGFβ) Ab. Anti-TGFβ Ab reduced: (A) (a-d) areas of ...
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