transgenic mice
Transgenic mice for a tamoxifen-induced, conditional expression of the Cre recombinase in osteoclasts.
... of transgenic mice and characterization The CtsKCreERT2 construct was injected into oocytes of C57BL/6 and FVB ...fifty mice, seven C57BL/6 and two FVB conditional Cre positive strains were ...
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Bridging the species divide: transgenic mice humanized for type-I interferon response.
... generated transgenic mice that harbor humanized type I interferon receptors (IFNARs) enabling the study of type I human interferons (Hu-IFN-Is) in ...IFNAR) mice encode transgenic variants of ...
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Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice.
... use transgenic mice with 2-3-fold over-expression of human GFP-tagged wild-type α-synuclein (Syn-GFP), which mimics duplication and triplication mutations found in some human patients ...Syn-GFP ...
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Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.
... TghCBS60.4 mice To determine whether overexpression of CBS has consequences on brain physiology, we performed a series of electrophysiological recordings in hippocampal slices from control and transgenic ...
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Protective efficacy of VP1-specific neutralizing antibody associated with a reduction of viral load and pro-inflammatory cytokines in human SCARB2-transgenic mice.
... BALB/C-suckling mice were reported to be susceptible to genotype C of EV71 infection to induce neurological pathology using a mouse-adapted but not clinically isolated virus in these experiments[8,23–25] or using ...
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Utrophin up-regulation by an artificial transcription factor in transgenic mice.
... Vp16-Jazz-transgenic mice that specifically over-express the utrophin gene at the muscular ...a transgenic mouse expressing an artificial gene coding for a zinc finger based transcription ...Jazz ...
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Therapeutic Effects of α1-Antitrypsin on Psedumonas aeruginosa Infection in ENaC Transgenic Mice.
... ENaC transgenic mice with PA infection were used as a CF-like ...model. Mice were intratracheally treated with PA or saline (control) in a fibrin ...ENaC transgenic mice received three ...
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Hemizygous Le-Cre transgenic mice have severe eye abnormalities on some genetic backgrounds in the absence of LoxP sites.
... Tg/2 mice (full name Tg(Pax6-cre,GFP)1Pgr; MGI number 3045749) [1] were ob- tained from Dr Ruth Ashery-Padan and Prof Peter Gruss (Max Plank Institute for Biophysical Chemistry, Goettingen, Germany) on an inbred ...
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IL-15 deficiency promotes tumor growth in tax transgenic mice
... 15th International Conference on Human Retroviruses:. HTLV and Related Viruses[r] ...
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Increased abscess formation and defective chemokine regulation in CREB transgenic mice.
... In mice, preputial glands are modified sebaceous glands that produce pheromones influencing important social features includ- ing sexual attractiveness, promotion of the estrous cycle in grouped females, ...
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The temporal expression pattern of alpha-synuclein modulates olfactory neurogenesis in transgenic mice.
... All mice were kept in a 12 h light/dark cycle and had access to food and water ad ...Tg mice expressing WTS under the regulatory control of the mThy1 promoter belonging to the high expression line 61 ...
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2 receptors to Gs and inhibitory G pro- tein (Gi ) is evident in cardiac myocytes from new-
... Transgenic mice overexpressing Gq also ex- hibit a myopathic phenotype associated with car- diac hypertrophy and fibrosis, which recapitulates that observed in pressure overload hypertrophy (D’Angelo et ...
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Neuronal nitric oxide synthase-rescue of dystrophin/utrophin double knockout mice does not require nNOS localization to the cell membrane.
... mdx mice significantly reduced muscle fiber damage ...TG+/mdx mice, we anticipated a similar effect on fiber ...TG+/dko mice indicating that a reduction of muscle necrosis did not contribute to the ...
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Dejia Li 1, , Akshay Bareja
... BL10 mice, we observed uniform dystrophin, syntrophin and nNOS expression at the ...mdx mice, utrophin was upregulated and elevated utrophin resulted in low- level syntrophin staining at the ...u-dko ...
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Rev. Bras. Psiquiatr. vol.35 suppl.2
... generating Ab peptides, which are amyloidogenic and are prone to form plaques (Figure 1). However, there is no direct correlation between the number of cortical plaques and cognitive deficit in AD patients, and many ...
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Split-cre complementation indicates coincident activity of different genes in vivo.
... transgenic mice. C–E: NCre and CCre were transgenically expressed in mice using the PLP ...promoter. Transgenic mouse lines expressing NCre (line PCND) and CCre (line PCCR) were crossed to ...
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Local induction of immunosuppressive CD8+ T cells in the gut-associated lymphoid tissues.
... the VILLIN-HA/CL4-TCR transgenic mice we demonstrated the specific expression of CCL4. Although CCL4 is commonly regarded as proinflammatory, several lines of evidence are compatible with an additional, ...
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Paradigmenwechsel bei der Alzheimer-Krankheit: Intrazelluläre Aggregation von Amyloid-beta verursacht den Zellverlust unabhängig von extrazellulären Plaques
... in transgenic mice with five familial Alzheimer’s disease mutations: potential factors in amyloid plaque ...in mice: a role for intraneuronal ...in transgenic mice expressing both ...
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Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis.
... in mice treated with Clo-L, GdCl3 or ...competent transgenic mice), or they never returned (in the case of mice infected with the replication-deficient adenovirus) (not ...utilizing ...
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Identification of optogenetically activated striatal medium spiny neurons by Npas4 expression.
... Optogenetics is a powerful neuromodulatory tool with many unique advantages to explore functions of neuronal circuits in physiology and diseases. Yet, interpretation of cellular and behavioral responses following in vivo ...
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