β-cell
Latent Autoimmune Diabetes in Adults: Autoimmune Diabetes in Adults with Slowly Progressive β-cell Failure
... pancreatic β-cell destruc- tion and insulin deiciency, although some subjects show lack of autoantibodies to pancreatic ...complete β-cell mass loss in T1D, simple or unique patterns may not ...
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Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes.
... promote β- cell proliferation and prevent β-cell apoptosis, particularly in rodents [41, 42], whereas those effects may not necessarily translate to humans [42, ...assess β-cell ...
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Circulating Differentially Methylated Amylin DNA as a Biomarker of β-Cell Loss in Type 1 Diabetes.
... (T1D), β-cell loss is silent during disease ...of β-cell-derived DNA in the blood can serve as a biomarker of β-cell death in ...by β-cells in the ...of ...
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Allantoin ameliorates chemically-induced pancreatic β-cell damage through activation of the imidazoline I3 receptors
... protect β-cells from apoptosis (Cernea, 2011; Liu et ...pancreatic β-cell protection via the I3 ...pancreatic β-cells induced by a low dose of streptozotocin ...
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Monosodium Glutamate Dietary Consumption Decreases Pancreatic β-Cell Mass in Adult Wistar Rats.
... by β-cell regeneration ...the β-cell mass during ...and β-cell [26] injury and may represent a reactive phenomenon in our experimental ...
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Reduced pancreatic β-cell mass is associated with decreased FoxO1 and Erk12 protein phosphorylation in low-protein malnourished rats
... present decreased glucose-stimulated insulin secretion and reduced islet insulin content (26), but also demonstrate a compensatory increase in Irs-2 protein in pancreatic islets, leading to islet hyperplasia (23,27). In ...
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Role of the mitochondria in immune-mediated apoptotic death of the human pancreatic β cell line βLox5.
... Treatment of bLox5 cells with rhIFNc and rhTNFa resulted in activation of Caspases 8 and 3 (Fig. 4B). Confirmed pan-caspase inhibition failed to completely prevent death (Fig. 4C, D), suggesting that cytokines kill these ...
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Reduction in adiposity, β-cell function, insulin sensitivity, and cardiovascular risk factors: a prospective study among Japanese with obesity.
... Reductions in BMI, VFAT, and waist circumference were associated with a decrease in HOMA-b. Importantly, a previous study has shown that HOMA b-cell function, another measure of b-cell function, is elevated ...
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Contribution of a non-β-cell source to β-cell mass during pregnancy.
... for cell proliferation ...enter cell cycle and ...promoting cell replication and inhibiting cell differentiation and it inhibits expression of Ngn3 [28,29], whereas Sox9 plays a role in the ...
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Hyperuricemia causes pancreatic β-cell death and dysfunction through NF-κB signaling pathway.
... The activation of the NF-kB-iNOS-NO signaling pathway has been reported to lead to the cytotoxicity and apoptosis in b-cells in both type 1 and type 2 diabetes [40,41]. In unstimulated cells, the NF-kB heterodimers are ...
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EGFR signaling promotes β-cell proliferation and survivin expression during pregnancy.
... of the largest islets, rather than by formation of new islets during pregnancy. Major weakness of the OPT analysis is that its detection limit excludes very small islets, i.e. less than 5610 3 um 3 in size. Consequently, ...
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Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/β-catenin antagonist Chibby.
... At the ultrastructural level, a typical columnar epithelium composed of Clara cells and ciliated cells was observed in the proximal airway epithelium of control Cby +/+ mice (Figure 7C). On the other hand, irregular ...
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Lymphotoxin-β receptor in microenvironmental cells promotes the development of T-cell acute lymphoblastic leukaemia with cortical/mature immunophenotype.
... 1 β 2 expression in emerging malignant thymocytes activates an NF‐κB‐dependent transcriptional programme in thymic microenvironmental cells that promotes T‐cell ...
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Ciclofuncionalização de β,-enamino Ésteres e β-hidróxi ésteres
... Os β -ceto ésteres 1 e 2 (Figura 1) foram preparados através de uma adaptação do método clássico de alquilação 29 onde etóxido de sódio, utilizado como base para gerar o monoânion do acetoacetato de etila, é ...
116
Inhibiting α-synuclein oligomerization by stable cell-penetrating β-synuclein fragments recovers phenotype of Parkinson's disease model flies.
... mammalian cell culture, which serves as a model for PD, SH- SY5Y5 cells over-expressing wild type a-syn were ...induce cell differen- tiation ...the cell membrane was marked using Phalloidin reagent ...
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Repare que para quaisquer α e β
... de β o ângulo AÔB e de α o ângulo BÔD. Veja que α e β são os únicos ângulos, dentro de uma volta na circunferência, que possuem esse valor (EC) de ...= β + 180º satisfaz essa ...= β é outra ...
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Talassemia β intermediária em gestante
... talassemia β é a forma considerada clinicamente a mais importante dentre as talassemias, em virtude do grau de morbidade e mortalidade, em consequência da anemia ...talassemia β intermediária, identificada ...
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Avaliação da atividade anti-inflamatória da β-lapachona e do complexo de inclusão da β-lapachona em ciclodextrina
... Para avaliar os efeitos da inflamação crônica, foi empregado o método descrito por Newbould (1963), com pequenas modificações. Foram utilizados quatro grupos contendo oito animais cada: grupo 1: veículo; grupo 2: ...
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S100 calcium-binding protein A6 promotes epithelial-mesenchymal transition through β-catenin in pancreatic cancer cell line.
... influences cell fate, proliferation, polarity, and cell death during embryonic development, as well as tissue homeostasis in ...and cell surface re- ceptor, in addition to cytoplasmic components and ...
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Vascular endothelial dysfunction in β-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO.
... [20]. Cell-free plasma hemoglobin reacts rapidly with, and deactivates, NO ...sickle cell disease, another hemoglobinopathy inducing chronic hemolytic anemia, have shown increased intravascular ...
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