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[PDF] Top 20 Clinical and genetic factors predicting response to therapy in patients with Crohn’s disease

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Clinical and genetic factors predicting response to therapy in patients with Crohn’s disease

Clinical and genetic factors predicting response to therapy in patients with Crohn’s disease

... USA) and SNPassoc 1.6 pack- age in R ...(OR) with 95% confidence interval ...test and univariate logistic ...performed to adjust for potential con- founding ...models, and ... See full document

11

Risk factors for metabolic bone disease in Crohn's disease patients

Risk factors for metabolic bone disease in Crohn's disease patients

... Z-scores and fat ...seemed to differ in patients with a Z-score lower or higher than ...2.0. In a previous study performed in this same population, we observed that a ... See full document

8

Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort.

Clinical outcome of HIV-infected patients with sustained virologic response to antiretroviral therapy: long-term follow-up of a multicenter cohort.

... of patients with sustained virologic response to antiretroviral ...aimed to assess predictors of unfavorable clinical outcome in patients who maintain viral ... See full document

7

Clinical Factors and Disease Course Related to Diagnostic Delay in Korean Crohn's Disease Patients: Results from the CONNECT Study.

Clinical Factors and Disease Course Related to Diagnostic Delay in Korean Crohn's Disease Patients: Results from the CONNECT Study.

... addition, in the last two decades, several studies reported that an early intensive treatment with immunosuppressive agents or biologics showed better clinical outcomes than conventional treatment ... See full document

13

Genetic variants related to angiogenesis and apoptosis in patients with glioma

Genetic variants related to angiogenesis and apoptosis in patients with glioma

... tumor in adults, is highly aggressive and associated with a poor ...were to evaluate the association of genetic polymorphisms related to angiogenesis and apoptosis ... See full document

6

Switching multiple sclerosis patients with breakthrough disease to second-line therapy.

Switching multiple sclerosis patients with breakthrough disease to second-line therapy.

... balance in the risk/benefit ratio of natalizumab versus immunosuppression as second-line therapy is unknown and may be influenced not only by potential adverse effects but also by factors such ... See full document

5

Genetic, laboratory and clinical risk factors in the development of overt ischemic stroke in children with sickle cell disease

Genetic, laboratory and clinical risk factors in the development of overt ischemic stroke in children with sickle cell disease

... Cerebrovascular disease, particularly stroke, is one of the most severe clinical complica- tions associated with sickle cell disease and is a significant cause of morbidity in ... See full document

16

Male breast cancer: prognostic and predictive factors of response to therapy

Male breast cancer: prognostic and predictive factors of response to therapy

... stated to justify the disparities between frequencies of classical FBC subtypes in ...tumours in female patients are associated with older age and post- menopausal status [ 48 ... See full document

188

and kidney disease risk in HIV patients taking combined  therapy

and kidney disease risk in HIV patients taking combined therapy

... microalbuminuria, and suggested it could be a sign of endothelial dysfunction and microvascular disease and not an advanced HIV in- fection, predicting a future vascular ...Some ... See full document

8

Psychological factors associated with response to treatment in rheumatoid arthritis

Psychological factors associated with response to treatment in rheumatoid arthritis

... is in remission may be a direct effect of therapy on the biology of depression, at least as much as an indirect effect through improvement in the symptoms of RA and its impact on the patient’s ... See full document

13

Clinical, radiologic, and genetic features of Korean patients with Mucopolysaccharidosis IVA

Clinical, radiologic, and genetic features of Korean patients with Mucopolysaccharidosis IVA

... Korean patients with MPS IVA had severe skeletal problems and almost all had a severe phenotype by the time they were ...those patients with mild symptoms or deformities did not suspect ... See full document

8

Socio-Economic and Clinical Factors as Predictors of Disease Evolution and Acute Events in COPD Patients.

Socio-Economic and Clinical Factors as Predictors of Disease Evolution and Acute Events in COPD Patients.

... of Disease Study estimated that COPD will become the third leading cause of death worldwide by 2020 ...[2]. In addition, considering the sum of years lost because of premature mortality and years of ... See full document

10

Hypokalemia, its contributing factors and renal outcomes in patients with chronic kidney disease.

Hypokalemia, its contributing factors and renal outcomes in patients with chronic kidney disease.

... cohort to investigate the impact of integrated CKD care program on clinical outcomes from a diverse group of CKD stage 1–5 ...CKD patients not on renal replacement ...decrease in eGFR ... See full document

9

Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia.

Clinical and Microbiological Factors Associated with High Nasopharyngeal Pneumococcal Density in Patients with Pneumococcal Pneumonia.

... associated with a medium/high S-Ig titer against the patient´s own pneumococcal ...many patients with short symptom duration had high S-Ig titers and that S-Ig ... See full document

13

Dental caries, prevalence and risk factors in patients with Crohn's disease.

Dental caries, prevalence and risk factors in patients with Crohn's disease.

... Crohn’s disease (CD) is a granulomatous chronic inflammatory disease that can affect any region of the gastrointestinal tract, although it is usually localized to the small intestine and colon ... See full document

5

Genetic factors and cardiovascular disease

Genetic factors and cardiovascular disease

... years and it is only recently that its growth has become exponential, particularly in cardiovascular ...up-to-date with recent developments in this area in order to ... See full document

5

Genetic variation in interleukin 28B and response to antiviral therapy in patients with dual chronic infection with hepatitis B and C viruses.

Genetic variation in interleukin 28B and response to antiviral therapy in patients with dual chronic infection with hepatitis B and C viruses.

... SNPs in the natural course and IFN-based treatment outcomes of HCV and HBV infection ...[16,17,28]. In the current study, we found that rs80λλλ17 G variants (TG +GG) and rs12λ7λ860 T ... See full document

6

Clinical and immune response to homeopathic treatment among HIV patients: case report

Clinical and immune response to homeopathic treatment among HIV patients: case report

... treatment to prevent the progression of infection into the acquired immunodeficiency syndrome ...(AIDS). In the present article we report one randomly selected case to describe the results achieved ... See full document

12

High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy

High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy

... reported in studies from other ...PCP in Kampala, Uganda, documented that all 13 isolates of ...ascribed to population-level selection pressure due to sulfa drug use for treatment of malaria ... See full document

10

Clinical and Genetic Characterization of Portuguese Patients with Pseudohypoparathyroidism Type Ib

Clinical and Genetic Characterization of Portuguese Patients with Pseudohypoparathyroidism Type Ib

... deletion in the STX16 gene, comprising a putative cis-acting control ele- ment for the imprinting of the GNAS locus [ 11 ...deletion in their mother and, possibly, in the grandfather, explains ... See full document

7

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