[PDF] Top 20 Exploring the molecular mechanisms underlying head and neck cancer cachexia

... life and the clinical outcome of disease treatment ...of cancer patients suffer from cachexia at the time of ...that cachexia contributes to cancer death in approximately ... See full document

... Head and neck cancers are among the most prevalent tumors in the ...radiation and chemotherapy), the overall survival rate for SCCHN has not significantly improved in ... See full document

... regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 32 cancer groups, 1990 to 2015: a systematic ... See full document

... of the transforming growth factor-β superfamily, is almost exclusively expressed in the skeletal muscle, where it negatively regulates myocyte differentiation/growth and determines muscle size (Liu ... See full document

... Finally, the cutoff value that separated the post-treatment dysphonic individuals from head and neck cancer of the vocally healthy was determined based on the ... See full document

... 50) and HNSCC (n = 100) were collected on gelatin-coated ...brief, the sections were deparaffinized in xylene, hydrated in gradient alcohol, and pre-treated in a microwave oven for 10 min at 800 W ... See full document

... [17]. The PDXs that we have generated, utilized and described throughout this paper were implanted in a heterotopic fashion since HNCs were grown subcutaneously in the ...[9,10], and renal ... See full document

... of the A>G transition at position 2756 on the MTR gene (5-methyltetrahydrofolate-homocysteine methyl- transferase), involved in folate metabolism, may be a risk factor for head and ... See full document

... of the other variables considered, including neck node involvement and EGFR expres- ...of the variables used in a ‘‘conventional’’ evaluation of risk factors remained significant when ... See full document

... of molecular markers in blood would predict the development of cancer in its earliest stage or in precancerous ...indices and role of WBC count in the diagnosis of malignancies of ... See full document

... later, the patient presented once again due to recurrent syncope in the last ...vision and dizziness, with no complaints of chest pain, dyspnea or palpitations, followed by loss of muscle tone ... See full document

... evaluate the presence of vocal signs and symptoms and the vocal function in patients with dysphagia treated for head and neck cancer – HNC and identify ... See full document

... evaluated the association of MMP polymorphisms and HNC risk using ORs and 95% ...CIs. The significance of pooled ORs was estimated via a Z test ...when the P value for heterogeneity was ... See full document

... to the total amount of feeding, building, sanitation and brooding care that the nestlings received I used generalized linear mixed models (GLMMs) with number of feeding, building or sanitation visits ... See full document

... from the Ontario Institute of Cancer Research, the Canadian Institutes of Health Research, and the ...in Head and Neck Cancer Research. The authors ... See full document

... which the Perls stain revealed marked iron ...on the SE PD/T2-weighted images and thus was correctly as- signed as metastatic in reading ...to the relatively thick slices that were obtained, ... See full document

... for cachexia and Wasting disorders, european Palliative care research collaborative; special interest Group on cachexia and anorexia of the european society for enteral and ... See full document

... applying the internal validation method as described in detail in Section ...than the original one (0.654) but the difference is very ...of the model is 0.645, if all other aspects of ... See full document

... evade the immune response, surviving inside ...prevalence and mortality are decreasing, however, drug resistance to the current treatments makes TB eradication progressively ...by the innate ... See full document

... cells and mast cells 3 . Entry of T- lymphocytes into the arterial intima is facilitated by their binding to adhesion molecules such as VCAM ...within the arterial intima, T-cells may become ... See full document