[PDF] Top 20 Genetic alterations in head and neck squamous cell carcinomas

... Genetic alterations leading to loss of nor- mal function of the TP53 tumor suppressor gene is believed to contribute to the develop- ment of the majority of human cancers ...17p13.1 and consists of ... See full document

... markers in blood would predict the development of cancer in its earliest stage or in precancerous ...indices and role of WBC count in the diagnosis of malignancies of the head ... See full document

... form and the last to encapsulate during the embrionary pro- ...importance in the prognosis of SCC in the head and neck region has emerged relatively ... See full document

... [20] and widely used in many recent studies concerning head and neck tumors [21], melanoma [22], breast [3,23], ovarian [24], and colorectal [25] ...selected and scored ... See full document

... by head and neck squamous cell carcinoma (HNSCC) cell lines, KB, KB16, and HEP, to induce the secretion of various cytokines from peripheral blood mononuclear cells ... See full document

... protein in head and neck squamous cell carcinoma (HNSCC) in order to analyze its association with clinicopathologic factors and overall survival of ...Material ... See full document

... GSTM1 and GSTT1 null genotype confers susceptibility to HNSCC in the overall ...monohalomethane and ethylene oxide ...GSTM1 and GSTT1 null genotype may theoretically confer a higher risk to ... See full document

... described in the Materials and ...using cell lysates from the human fibroblast GM637 cells or the XP30RO fibroblast cells derived from XP-V ...shown in Figure 1b, the antibody recognized a ~80 ... See full document

... cells and monocytes and appear to be indispensable for initiating appropriate immune ...organs in order to present processed antigens to lymphocytes and to stimulate immune responses ...cells ... See full document

... 2009 in the head and neck surgery departments of five hospitals of the Brazilian Head and Neck Genome Project, Gencapo, a collaborative consortium of research groups from ... See full document

... MAPK, and Src signaling pathways to induce various physiological functions including anti-apoptosis and cell proliferation, angiogenesis, anoikis and metastasis ...enhanced in the CR ... See full document

... Head and neck squamous cell carcinoma (HNSCC) is the sixth most common type of cancer and causes 350,000 cancer deaths worldwide every year ...arise in the paranasal ... See full document

... of head and neck squamous cell carcinoma in smokers (OR = ...1.1-2.5) and that the GSTT1 null genotype [-] may protect individuals against the development of this ... See full document

... miR-203 and miR-205. The histological analyses found 45 positive FNA and 68 negative ...approaches in detecting negative lymph nodes and of 93.3% in classifying positive ones (Kappa ... See full document

... activation and detoxification may interfere with susceptibility to head and neck ...GSTT1 and GSTM1 null polymorphisms and the risk of head and neck ... See full document

... the cell-cycle. Molecular genetic studies have revealed that deletions in CDKN2A occur frequently in ...involved in tumor progression, the clinical impact and prognostic ... See full document

... (82%) and four females ...white, and 9.1% were black. These patients presented squamous cell carcinomas and were submitted to head and neck radiotherapeutic ... See full document

... subjects in this study; 100 (84 male and 16 female; mean age - ...of head and neck squamous cell carcinoma, seen at a university hospital in the Northeastern part ... See full document

... Squamous cell carcinoma (SCC) accounts for approximately 95% of the malignancies of the oral cavity 1 and represents a public health problem in many countries due to the high morbi-mortality ... See full document

... with head and neck squamous cell carcino- mas and 24 healthy ...expression and enzyme-linked immunosorbent assay was employed to measure serum and salivary ... See full document