[PDF] Top 20 Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) null polymorphisms and the risk of hypertension: a meta-analysis.

... between the generation of reactive oxygen species and the diminished activity of antioxidant enzymes [3], plays an important pathophysi- ological part in the development ... See full document

... The glutathione S-transferases M1 (GSTM1) and T1 (GSTT1) genes code for the cytosolic enzymes GST-m (mu) and GST-q (theta), ...involving the conjugation between ... See full document

... Secondly, the association of GSTM1 polymorphism with many types of diseases is documented by several stud- ies, which indicate that individuals homozygous for the GSTM1*0 allele seem to have a ... See full document

... assessing the association of GSTM1 and GSTT1 poly- morphism with generalized vitiligo, we noted that there were no differences between either GSTM1+/null or GSTT1+/null poly- morphism ... See full document

... distribution of polymorphisms related to glutathione S-trans- ferases (GST) has been described in different populations, mainly for white ...evaluated the distribution of GST mu ... See full document

... prostate and hepatocellular cancer, GSTA1*B allele with lower transcriptional activity was associated with increased ...to the most promiscuous GSTs that acts upon a broad range of substrates which ... See full document

... in the literature data, GSTT1-null and GSTT1-null/GSTM1-null genotypes have consistently been con- sidered risk factors for the development of T2DM as reported by a ... See full document

... one of the predictive factors for breast cancer and the extent of the density is directly related to ...by the genes that codify for the proteins involved in ... See full document

... gene polymorphisms, it is possible that the combinations of certain genotypes may be more discriminating as risk factors for HCC than a single locus ...Among the 34 studies included in ... See full document

... this meta-analysis. First of all, even though we performed subgroup analyses stratified by ethnicity and control source, the heterogeneity for GSTM1 polymorphism among the ... See full document

... safeners and pharmaceuticals (Hershey and Stoner 1991, Dixon et ...a glutathione S-transferase, lambda class gene from rice, which showed response to ...activity of GST (Hu et ... See full document

... deletion and it has been recently proposed to reflect differential trans-activation of TLR2 promoter constructs and expression levels of TLR2 ...for the risk of different ... See full document

... safeners and pharmaceuticals (Hershey and Stoner 1991, Dixon et ...a glutathione S-transferase, lambda class gene from rice, which showed response to ...activity of GST (Hu et ... See full document

... efect of (BaP) on CYP1A1 was evaluated in Acipenser persicus ...induction of both xenobiotics and maximum value was achieved at 72 ...result of BNF or BaP were obtained, such as Arctic charr, ... See full document

... era of globalization is impact on the necessity for each country to be able to compete with the world competition that tends ...with the concept of state sovereignty reduction, ... See full document

... containing the EO did not have any alterations in acetylcholinesterase, ecto-nucleoside triphosphate diphosphohydrolase and 5’nucleotidase activity in the brain or superoxide dismutase activity in ... See full document

... between the -260C/T polymorphism and risk of cancer in the population-based subgroup was found under recessive ...model. The results seem to contradict the observations ... See full document

... O gene KLK3 ou PSA codifica uma protease do tipo serina, produzida predominantemente pela próstata, mais especificamente pelas células secretoras prostáticas. Apesar de PSA ser encontrada em maior quantidade no sémen, ... See full document

... that the results of one independent study by Ulrich et ...considerably, and inclusion of this study was primarily responsible for the significant difference observed in the ... See full document

... in the meta-analysis because the number of studies was considerably smaller than that needed for the achievement of robust ...size meta-analysis, they could ... See full document