[PDF] Top 20 HIV-1 diversity and drug-resistant mutations in infected individuals in Changchun, China.
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HIV-1 diversity and drug-resistant mutations in infected individuals in Changchun, China.
... replication and thus is responsible for passing on mutations, including those conferring antiviral drug resistance, to the next generation of HIV-1 ...antiviral drug resistance ... See full document
8
Different HCV genotype distributions of HIV-infected individuals in Henan and Guangxi, China.
... 1,112 HIV-infected individuals in the provinces of Henan and Guangxi, ...obtained in Henan were collected from various risk groups, including 187 FBDs, 33 individuals with ... See full document
11
Prevalence of Resistance-Associated Mutations in Human Immunodeficiency Virus Type 1-Positive Individuals Failing HAART in Rio de Janeiro, Brazil
... nucleosidic and non-nucleosidic reverse transcriptase inhibitors (NRTIs and NNRTIs, respectively) and protease inhibitors (PIs) ...[1,2]. In order to improve clinical and virological ... See full document
5
Different frequencies of drug resistance mutations among HIV-1 subtypes circulating in China: a comprehensive study.
... of HIV drug resistance is threatening the overall success of free HAART in ...on drug-resistant mutations, however, most of which were based on subtype ...of ... See full document
9
Daniela M Cerqueira ++ , Regina MS Amorim, Ruiter R Silva, Geni NL Camara, Marcelo M Brígido, Cláudia RF Martins+
... type 1 (HIV-1) genetic diversity and resistance becomes ...pivotal. In this work our purpose was to describe the genetic variability; prevalence of drug-resistance ... See full document
6
Mutations Related to Antiretroviral Resistance Identified by Ultra-Deep Sequencing in HIV-1 Infected Children under Structured Interruptions of HAART.
... of HIV infection; however, problems that emerge during its administration, such as chronic toxicity, poor adherence and costs, are factors contributing to treatment failure and limiting its long-term ... See full document
11
Prevalence of transmitted HIV-1 antiretroviral resistance among patients initiating antiretroviral therapy in Brazil: a surveillance study using dried blood spots
... TDR mutations to NRTI than to NNRTI in individuals with longstanding infections, in contrast to individuals with recent HIV infections ...NRTIs and 4.9% to NNRTIs. ... See full document
7
Recent Transmission Clustering of HIV-1 C and CRF17_BF Strains Characterized by NNRTI-Related Mutations among Newly Diagnosed Men in Central Italy.
... patients in the clusters were infected by an R5 tropic ...also in the setting of the same cluster (from 14.3% to 48.6% in C cluster, and ...25.3% and 96.2% in CRF17_BF ... See full document
17
Faster HIV-1 Disease Progression among Brazilian Individuals Recently Infected with CXCR4-Utilizing Strains
... strains in Brazil [ref] ...patients in lower CD4+ T cell count strata, whereas the prevalence of the classical GPGR strains remains unchanged and the prevalence of strains presenting other amino ... See full document
9
HIV-1 SUBTYPES AND MUTATIONS ASSOCIATED TO ANTIRETROVIRAL DRUG RESISTANCE IN HUMAN ISOLATES FROM CENTRAL BRAZIL Daniela Marreco Cerqueira1 , Eduardo Dias Ramalho1 ; Claudiner Pereira Oliveira1 ; Ruiter Roberto Silva2; Miriam Franchini2 ; Maria Sueli Soare
... person infected with a RNA virus, we detected many polymorphisms in the sequences ...polymorphism in our study was N37S ...(54 and 76%) in previous Brazilian studies ...position: ... See full document
6
HIV-1 diversity, drug-resistant mutations, and viral evolution among high-risk individuals in phase II HIV vaccine trial sites in southern China.
... observed in the V3 loop within the Env fragment of both CRF07_BC and CRF08_BC may be determined by local cell tropism, since V3 is one of the most important determinants of viral tropism and ... See full document
10
Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naive HIV-Infected Individuals.
... interest in recent years as an aid for treating individuals already infected with HIV-1 as part of HIV-1 cure strategies [1, ...control HIV-1 ... See full document
19
Effect of Natural Polymorphisms in the HIV-1 CRF02_AG Protease on Protease Inhibitor Hypersusceptibility
... diverse HIV-infected individuals may be a misnomer because clinical response to treatment is evaluated in relation to subtype B infections while drug susceptibility of the infecting ... See full document
7
Tg Ahmad Akram Tg Mohd Ariffina , Rafidah Hanim Shueba
... morbidity and mortality in human immunodeficiency virus 1 (HiV-1) infected ...resistance in these children is a major public health problem due to lack of availability of ... See full document
5
Highly Active Antiviral Therapy among Patients with HIV Infections
... 11. Gulick R.M., Ribaudo H.J., Shikuma C.M., Lustgarten S., Meyer W.A., Klingman K., Squires K.E., Snyder S., Kuritzkes, DR. ACTG 5095: A Comparative Study of Three Protease Inhibitor-Sparing Antiretroviral Regimens for ... See full document
6
Determinants of Smoking and Quitting in HIV-Infected Individuals.
... outcomes in a health care system-based longitudinal observational cohort of HIV-infected patients and matched ...status in this large cohort, we developed and validated an ... See full document
12
The association of HLA-DRB1 alleles and drug use with HIV infection in a Chinese Han Cohort
... polymorphism and infectious dis- ...1201/1202 in patients with hepatitis B using PCR-SSP technology, and drew a conclusion that allele GF of HLA-DRB1 *1301/1302 among patients with chronic hepatitis ... See full document
6
CLÍNICA E EFEITOS DO FÁRMACO A LONGO TERMO
... 114. Haas DW, Smeaton LM, Shafer RW, Robbins GK, Morse GD, Labbe L, Wilkinson GR, Clifford DB, D'Aquila RT, De Gruttola V, Pollard RB, Merigan TC, Hirsch MS, George AL Jr, Donahue JP, Kim RB. Pharmacogenetics of ... See full document
137
Epidemiological Surveillance of HIV-1 Transmitted Drug Resistance in Spain in 2004-2012: Relevance of Transmission Clusters in the Propagation of Resistance Mutations.
... regions and times, the World Health Organization (WHO) has recommended the adoption of a consensus genotypic definition of transmitted HIV-1 drug resistance ...surveillance ... See full document
13
Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium
... Whilst drug resistance in ...of mutations in the genes that code for the drug targets, efflux pump activity was only recently recognized to play a significant role in the ... See full document
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