[PDF] Top 20 First insights on the presence of the unfolded protein response in human spermatozoa
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First insights on the presence of the unfolded protein response in human spermatozoa
... investigate the presence of HSF1, GADD34, eIF2α, and p-eIF2α (Ser51) in human sperm, sperm extracts corresponding to 30 µg of protein were resolved by 10% ... See full document
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Detailed kinetics of the direct allo-response in human liver transplant recipients: new insights from an optimized assay.
... is the use of CFSE-dilution in combination with software that calculates PF as a read-out ...Detection of responding cells by this technique is not dependent on the number ... See full document
12
Antiviral activity of a small molecule deubiquitinase inhibitor occurs via induction of the unfolded protein response.
... activity in both mock- and virally-infected samples compared to DMSO, but not compared to each other ...infection in (A) RAW ...5) in the presence of 5 mM WP1130 or DMSO ...at ... See full document
15
Yeast Bax inhibitor, Bxi1p, is an ER-localized protein that links the unfolded protein response and programmed cell death in Saccharomyces cerevisiae.
... upregulated in a wide range of human cancers. Studies in both mammalian and plant cells suggest that the BI-1 protein resides in the endoplasmic reticulum and is ... See full document
7
Polyunsaturated Branched-Chain Fatty Acid Geranylgeranoic Acid Induces Unfolded Protein Response in Human Hepatoma Cells.
... using the Quick- Gene RNA cultured Cell kit S (Wako) with QuickGene-810 (Kurabo, Osaka, ...using the Transcriptor First Strand cDNA Synthesis kit with random hexamers (Roche Diagnostics, Basel, ... See full document
20
Identification of the prion protein Doppel in spermatozoa and its impact in fertility
... cryoresistance of human and ovine sperm were compared based on different PRND polymorphisms, by analyzing the motility, vitality, concentration and morphology of fresh and thawed ... See full document
72
The anti-cancer IgM monoclonal antibody PAT-SM6 binds with high avidity to the unfolded protein response regulator GRP78.
... from human tumours induces apoptosis in tumour cells and is considered a potential anti-cancer ...is the unfolded protein response regulator GRP78, over-expressed externally ... See full document
11
OASIS/CREB3L1 is induced by endoplasmic reticulum stress in human glioma cell lines and contributes to the unfolded protein response, extracellular matrix production and cell migration.
... expression. The reason for this is reduction is unclear, although it may relate to the concentration of TG used and length of ...even in the absence of chemically-induced ... See full document
10
The bZIP Transcription Factor HAC-1 Is Involved in the Unfolded Protein Response and Is Necessary for Growth on Cellulose in Neurospora crassa.
... characterization of the unfolded protein response in ...focusing on the bZIP transcription factor ...studied in this fungus and we herein show it to display ... See full document
20
TCTEX1D4 interactome in human testis: unraveling the function of dynein light chain in spermatozoa
... SalI of pAS2-1 vector (Esteves et ...was first used to confirm the expression of the resulting fusion protein (GAL4-TCTEX1D4) and also to confirm that this protein did not ... See full document
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Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.
... evaluate the cytotoxicity of EGF-SubA in both normal human astrocytes and GNS cells, which have limited capacity of growing as viable colonies, we applied the xCELLi- gence ... See full document
8
Genetic interactions due to constitutive and inducible gene regulation mediated by the unfolded protein response in C. elegans.
... none of which appeared to be directly involved in ER protein folding, secretion, or ERAD (Table ...S2). The negligible role of worm atf-6 in regulating i-UPR genes involved ... See full document
14
Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors.
... The unfolded protein response (UPR) is a stress-induced cyto-protective mechanism elicited towards an influx of large amount of proteins in the endoplasmic ... See full document
12
The effect of a DeltaK280 mutation on the unfolded state of a microtubule-binding repeat in Tau.
... aggregates of Ab-amyloid (Ab) and intraneuronal tau aggregates, known as senile plaques and neurofibrillary tangles (NFTs), respectively ...focus on Ab amyloid in AD research, tau seems to play an ... See full document
12
The effect of UV radiation on DNA in the presence of
... 14 The system possesses a ventilation chamber for ozone removal, and a security system which only allows the lamp to be on if the door is ...ensures the security of the ... See full document
78
The response of human macrophages to β-glucans depends on the inflammatory milieu.
... Since the NF-kB family of transcription factors plays a major role in the transcriptional regulation of COX-2, we addressed the involvement of this ...activation of ... See full document
15
Notes on the police presence in the urban periphery of Salvador
... one of the pioneers in the initiative. Only the human ego can explain his decision, since, as we can see, all of his initial interest had been directed towards belonging ... See full document
22
HCV causes chronic endoplasmic reticulum stress leading to adaptation and interference with the unfolded protein response.
... most of these studies were performed not in the context of viral infection, but rather by using transfections of sub-genomic or full-length replicons, as well as cell lines (hepatocytes ... See full document
12
On the Recombination Rate Estimation in the Presence of Population Substructure.
... using the generator of the corresponding Wright-Fisher diffusion ...with the application of Pade approximations, this provided a way to evaluate two-locus probabilities efficiently for ... See full document
11
Evolution of the human immunodeficiency virus type 2 envelope in the first years of infection is associated with the dynamics of the neutralizing antibody response
... transmission of HIV-2 is a rare event that in Europe has only been documented in Portugal [30-34] and France ...study the phenotypic and molecu- lar evolution of HIV-2 Env in ... See full document
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