[PDF] Top 20 Modulation of inflammatory response associated with intervertebral disc degeneration
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Modulation of inflammatory response associated with intervertebral disc degeneration
... IVD degeneration (Anderson et ...removal with collagenase (Stern and Coulson 1976), papain (Roberts et ...depressurization of the NP (Masuda et ...expression of pro-inflammatory and ... See full document
283
Cordycepin inhibits LPS-induced inflammatory and matrix degradation in the intervertebral disc
... effects of cordycepin in an organ culture model. Although the permeability of the annulus fibrous and endplate is very limited, our previous and other studies have confirmed that LPS and bioactive molecules ... See full document
21
Acute mechanical injury of the human intervertebral disc: link to degeneration and pain
... to intervertebral discs (IVDs) is thought to contribute to degeneration and ...promotes degeneration remain ...(injured) of disc ...content with a reciprocal increase of ... See full document
14
The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage
... report of an association between the human aggrecan CS1 polymorphism and articular cartilage degeneration was in relation to bilateral osteoarthritis (OA) of the hand (Horton et ...consisted ... See full document
7
Divergent pro-inflammatory profile of human dendritic cells in response to commensal and pathogenic bacteria associated with the airway microbiota.
... DC response to potentially pathogenic ...DC response to non-typeable Haemophillus influenza associated with asthma and ...potent inflammatory response mediated by the classical ... See full document
10
The inflammatory response in the regression of lumbar disc herniation
... efficacy of conservative vs nonconservative treat- ...patients with the seques- trated subtype of LDH may be conservative due to the higher likelihood and faster rate of resolution in com- ... See full document
9
Modulation of early inflammatory response by different balanced and non-balanced colloids and crystalloids in a rodent model of endotoxemia.
... use of hydroxyethyl starch (HES) in sepsis has been shown to increase mortality and acute kidney ...knowledge of the exact mechanism by which several fluids, especially starch preparations may impair ... See full document
10
Identification of novel nucleus pulposus markers: Interspecies variations and implications for cell-based therapiesfor intervertebral disc degeneration
... ontogeny of the NP cells, which has been a subject of a long lasting ...NP of some species lacks cells with a notochordal morphol- ...expression of keratin and also brachyury (also ... See full document
10
Towards the use of mesenchymal stem cells secretome to treat intervertebral disc degeneration
... goal of this study was to evaluate the immunomodulatory capacity of secMSCs in degenerated ...culture of bovine IVDs stimulated with needle puncture and pro- inflammatory cytokines ... See full document
71
Association of abdominal obesity with lumbar disc degeneration--a magnetic resonance imaging study.
... the disc tissue, which may ultimately lead to the loss of cell viability, altered biosynthesis of extracellular matrix and enzymes, and eventually matrix remodelling, similarly to disc ... See full document
8
Quantitative T2 magnetic resonance imaging compared to morphological grading of the early cervical intervertebral disc degeneration: an evaluation approach in asymptomatic young adults.
... Comparison of T2 values with morphological grading revealed a stepwise decrease in NP T2 values with increasing Pfirrmann grade and a strong negative rank ...disorganization with increasing ... See full document
8
Poroelastic behaviour of the degenerating human intervertebral disc: a ten-day study in a loaded disc culture system
... results of this study indicate that the changing biomechanical properties of the disc show mostly a weak-to-moderate relation to degeneration, based on MRI ...absence of a strong ... See full document
12
Metabolic Syndrome Components Are Associated with Intervertebral Disc Degeneration: The Wakayama Spine Study.
... significantly associated with presence of DD in the cervical, thoracic, and lumbar ...strongly associated with DD than pres- ent OW ...ated with OW and obesity ...correlation ... See full document
11
Type II collagen-hyaluronan hydrogel – a step towards a scaffold for intervertebral disc tissue engineering
... causes of job-related disability with significant associated social and economic costs accounting for total annual direct healthcare costs estimated at between $50 to $90 billion each year in the USA ... See full document
15
Cell therapy for intervertebral disc repair: advancing cell therapy from bench to clinics
... transplantation of mesenchymal stem cells (MSCs) in disc degeneration ...transplantation of human MSCs into porcine models (Henriksson et ...injection of adipose tissue derived stem ... See full document
7
Immunomodulatory Nanoparticles for Intervertebral Disc Degeneration
... levels of pro-inflammatory cytokines and chemokines compared with LPS ...production of these cytokines. Furthermore, this enhancement was greater with the smaller NPs than with ... See full document
109
Interleukin 1 Polymorphisms Contribute to Intervertebral Disc Degeneration Risk: A Meta-Analysis.
... expression of IL-1 gene polymorphisms could be related to predis- position to ...genotype of IL-1α (+889C/T),when compared with the CC genotype, was significantly associated with higher ... See full document
12
Sports activity and hip, knee, shoulder and intervertebral disc arthroplasties
... effect of excessive axial loads for any sports activities; however, the joint biomechanics are ...preservation of both cruciate ligaments allows one to retain a large part of the physio- logical ... See full document
6
SPORTS ACTIVITY AND HIP, KNEE, SHOULDER AND INTERVERTEBRAL DISC ARTHROPLASTIES
... 95% of the athletes, occurring within the first 3 months in ...30.7% of the sample, with maximum sports performance reached after a mean time of ...85% of the sample showed ... See full document
6
Reverse engineering and rapid prototyping in intervertebral disc tissue engineering
... hydrogel with low cell adhesion characteristics, thus unwanted cell types, which generally require strong attachment to the surrounding extracellular matrix (ECM), or biomaterial, do not migrate and proliferate in ... See full document
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