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[PDF] Top 20 Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging

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Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging

Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging

... National Lung Cancer Screening Trial (NLST), 18 a large prospective randomized trial funded by the National Cancer Institute (NCI), to determine whether screening with low-dose CT, as ... See full document

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Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging

Non-Small Cell Lung Cancer: Screening, Diagnosis, and Staging

... a diagnosis may be confirmed by percutaneous biopsy of a soft tissue mass, lymph node, lytic bone lesion, bone marrow, pleural or liver lesion, or an adequate cell sample obtained from a malignant pleural ... See full document

7

Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer.

Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer.

... urine and serum) and the presence of pancreatic cancer, bladder cancer and breast cancer has been ...(DIGE) and tandem mass spectrometry to compare the pancreatic juice ... See full document

13

Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer.

Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer.

... initiated lung adenomas and that Bmi1 is a target of RAF signaling [19] we decided to investigate adenoma formation in the absence of ...BXB23 and BXB11 background did not yield a significant ... See full document

10

The prognostic value of phosphorylated AKT expression in non-small cell lung cancer: a meta-analysis.

The prognostic value of phosphorylated AKT expression in non-small cell lung cancer: a meta-analysis.

... papers and abstracts into meta-analysis because the required data was available only in full ...companies, and only one study didn’t give the antibody source ...time, and the omission of any study ... See full document

6

Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.

Regulation and novel action of thymidine phosphorylase in non-small cell lung cancer: crosstalk with Nrf2 and HO-1.

... Nrf2 and HO-1 in mucoepidermoid carcinoma of the lung, as the manipulation of Nrf2 or HO-1 levels led to concomitant modulation of TP levels in vitro and in vivo and HO- 1 expression ... See full document

12

Bevacizumab and ge fitinib enhanced whole-brain radiation therapy for brain metastases due to non-small-cell lung cancer

Bevacizumab and ge fitinib enhanced whole-brain radiation therapy for brain metastases due to non-small-cell lung cancer

... cancers and brain metastases indicated that the risks of cerebral hemorrhage were similar between treatments with and without bevacizumab ...VEGF and VEGFR, thereby lessening formation of new blood ... See full document

8

Analysis of Prognostic Factors in 541 Female Patients with Advanced Non-small Cell Lung Cancer

Analysis of Prognostic Factors in 541 Female Patients with Advanced Non-small Cell Lung Cancer

... (C) and response of first-line chemotherapy (D) are independent prognostic factors for female patients with advanced non-small cell lung ... See full document

6

SINGLE AGENT DOCETAXEL AS SECOND- LINE CHEMOTHERAPY FOR PRETREATED PATIENTS WITH RECURRENT NON- SMALL CELL LUNG CANCER

SINGLE AGENT DOCETAXEL AS SECOND- LINE CHEMOTHERAPY FOR PRETREATED PATIENTS WITH RECURRENT NON- SMALL CELL LUNG CANCER

... Lung cancer represents a major health problem ...of cancer- related death in Europe (1), with a 5- year survival of approximately 15% for all stages ...(2). Non- small cell ... See full document

4

Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.

Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.

... of lung cancer, especially when combined with the upregulation of an influential ...lost and how its expression can be restored in an effort to treat lung ...agents and the prostacyclin ... See full document

8

Immune checkpoint inhibitors for advanced non-small cell lung cancer: emerging sequencing for new treatment targets

Immune checkpoint inhibitors for advanced non-small cell lung cancer: emerging sequencing for new treatment targets

... results and the PD-L1 positivity threshold used for patient selection was the main difference between CheckMate-026 and ...EGFR and ALK wild ... See full document

11

PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells.

PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells.

... of cell-cell adhesions in epithelial cells is one of the earliest steps of tumor ...junction and its members (i.e., cadherins and catenins) plays a pivotal role in the promotion of ...FOXC2 ... See full document

12

Blood vessel invasion as a strong independent prognostic indicator in non-small cell lung cancer: a systematic review and meta-analysis.

Blood vessel invasion as a strong independent prognostic indicator in non-small cell lung cancer: a systematic review and meta-analysis.

... Publication and reporting bias also has to be ...covariates and only the studies that found significant results in univariate analysis performed multivar- iate analysis; thus, pooling the results may have ... See full document

8

Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy.

Polymorphisms of homologous recombination genes and clinical outcomes of non-small cell lung cancer patients treated with definitive radiotherapy.

... T241M and NBN E185Q) to be associated with various types of cancer risks, including cancers of the lung, breast, ovary, leukemia and head and neck ...breast cancer [22], XRCC2 ... See full document

9

Concomitant active tuberculosis prolongs survival in non-small cell lung cancer: a study in a tuberculosis-endemic country.

Concomitant active tuberculosis prolongs survival in non-small cell lung cancer: a study in a tuberculosis-endemic country.

... IIIB and 167 ...(13.9%) and pemetrexed in 5 ...nine and seventy-two patients were respectively placed on first-line target therapy and best supportive care ...studies and four ... See full document

7

The prognostic role of mTOR and p-mTOR for survival in non-small cell lung cancer: a systematic review and meta-analysis.

The prognostic role of mTOR and p-mTOR for survival in non-small cell lung cancer: a systematic review and meta-analysis.

... Meanwhile, several limitations existed in this meta-analysis should also be presented. First, the number of studies involved was relatively small, especially studies about mTOR expression. Pooled HRs would be ... See full document

13

Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer.

Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer.

... precursor cell, acquired genetic instability gives rise to subsequent generations expressing unique characteristics, such as activated oncogenes and tumor suppressor genes ...driver and passenger ... See full document

7

The Hemoglobin Level as a Prognostic Factor in Patients with Non-Small Cell Lung Cancer  Treated with Gemcitabine and cis-Platinum

The Hemoglobin Level as a Prognostic Factor in Patients with Non-Small Cell Lung Cancer Treated with Gemcitabine and cis-Platinum

... Anemia is a common finding in cancer patients. Up to 30% of patients with different types of tumors have been reported to suffer from anemia (6). This can be related to the disease process itself or to its ... See full document

4

Angiopoietin-2 and VEGF in non-small cell lung cancer prognosis: can vessel co-option have a role here?

Angiopoietin-2 and VEGF in non-small cell lung cancer prognosis: can vessel co-option have a role here?

... 70], and there is also evidence that it is deeply involved in lung metastases homing and progression [71, ...tenuous and plastic state by inducing loosening of endothelial cell ... See full document

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Loss of 4q21.23-22.1 is a prognostic marker for disease free and overall survival in non-small cell lung cancer.

Loss of 4q21.23-22.1 is a prognostic marker for disease free and overall survival in non-small cell lung cancer.

... 4q21.23 and RP11-1053C2: 4q22.1) and 3 (RP11-634D8: ...(RP11-570L13 and RP11-634D8: Spectrum Orange, RP11-1053C2: Spectrum Green; Enzo Life Sciences, ...specificity and quality of the ... See full document

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