[PDF] Top 20 Parathyroid hormone related-protein promotes epithelial-to-mesenchymal transition in prostate cancer.

... Parathyroid hormone-related protein (PTHrP) possesses a variety of physiological and developmental functions and is also known to facilitate the progression of many common cancers, ... See full document

... The protein concentrations of the samples were determined using a protein quantitation kit (KeyGEN BioTECH, Nanjing, ...subjected to 10% SDS-PAGE and transferred to a poly- vinylidene ... See full document

... tissues to establish secondary malignancies is a hallmark of cancer metastasis and cancer-related death ...[4]. In many cases, enhanced tumor cell migration as well as local and distant ... See full document

... TrkB in solid cancers [6–8], this is the first study to address the function of TrkB in human ...TrkB protein is expressed in human endometrium, and its expression may be greater ... See full document

... as epithelial cells lose their sedentary charac- teristics and gain a motile ...involved in wound repair, tissue regeneration, and fibrosis, is characterized by inflammation, and TGF-β signaling is ... See full document

... increase in the number of apoptotic cells in all breast cancer cells after treatment with PP as compared to control ...cells in breast cancer cells after treatment with PP. (C) ... See full document

... of cancer. TBP-2 is downregulated in various human cancer cells ...and promotes apoptosis [30]. In human T cell lymphocyte virus type 1 (HTLV-I)- infected T cells, TBP-2 regulates cell ... See full document

... incubated in a lysis buffer containing 20 mM Tris–HCl (pH ...Indianapolis, IN, USA) for 2 h on ice. Cell lysates were collected and protein content was determined using the Bradford method (Bio-Rad ... See full document

... likely to induce its nuclear re-localization that associated with the gain of a mesenchymal ...phenotype. In this model the loss of CDH1 expression is only an indirect proof but suggests that TWIST1 ... See full document

... carcinogenesis, promotes tumor growth and facilitates tumor cell metastasis ...prognosis in many types of cancer, including pancreatic cancer ...IL-6 promotes pancreatic cancer ... See full document

... binding to partially complementary sequences in target mRNAs to induce mRNA decay, translational repression or both 1 ...bind to hundreds of mRNAs, sometimes having a strong effect but more ... See full document

... imaging prostate cancer. Several other PSMA mAbs are currently in clinical trials to explore their application as imaging and therapeutic ...half-life in the circulation, and low ... See full document

... progression to the enhancement of chemotherapeutic response, among ...exposed to normoxia, hypoxia or hypoxia plus 20(S)-Rg3, respectively, for 24 h were ...performed to analyze effect of 20(S)-Rg3 ... See full document

... observed to be upregulated and associated with metastasis in several cancers including breast cancer ...conserved in several species (Fig. 2A). In an effort to determine whether ... See full document

... implicated in various types of human malignancies ...demonstrated in breast cancer, lung cancer, vulvar squamous cell carcinoma, follicular and papillary thyroid tumors, meningioma, and HCC ... See full document

... proliferation in the NAC-treated Nkx3.1 2/2 prostate, we hypothesized that elevated ROS in the ...2/2 prostate is activating an anti-proliferative pathway or inhibiting a pro-proliferative ... See full document

... Afadin protein in the human gastric mucosa. (A) AFDN gene expression in the stomach of 181 (114 uninfected and 67 ...Afadin in paraffin-embedded sections of the gastric mucosa of individuals ... See full document

... this hormone measured in the sea bream and flounder may indicate that in teleosts, in contrast to what is observed in mammals, PTHrP, in addition to paracrine and ... See full document

... found to be responsible for driving EMT, of which transforming growth factor-b (TGF-b) is a master inducer ...[13]. To examine whether sorafenib could impair TGF-b-induced EMT in epithelial ... See full document

... experience in population studies related to the methods of screening for prostate ...characteristics to the study population, were conducted, allowing the evaluation of the level of ... See full document