[PDF] Top 20 Skin barrier in atopic dermatitis: beyond filaggrin
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Skin barrier in atopic dermatitis: beyond filaggrin
... Atopic dermatitis (AD) is a highly prevalent dermatosis in the population, especially in ...prevalence in recent decad ranges from 10% to 20% in children and reaches 3% in ... See full document
7
Use of probiotics in atopic dermatitis
... involved in AD is dysfunc- tion in the skin barrier. Barrier defects in AD also seem to affect the intestinal mucosa, also the com- position of the intestinal microflora is ... See full document
5
Atopic dermatitis and vitamin D: facts and controversies
... with atopic dermatitis have genetically determined risk factors that affect the barrier function of the skin and immune responses that interact with environmental ...results in an ... See full document
9
Treatment implications of New Physiopathology Insights in Atopic Dermatitis
... – Atopic dermatitis is a chronic inflammatory skin disease that usually affects children, but can also start in ...severe atopic dermatitis are ...epidermal barrier ... See full document
5
Filaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population.
... analyses in the ...concomitant skin xerosis (P = ...3). In the QTL analysis, we found that ...frequencies in AD patients without asthma or AR were slightly higher than in patients with ... See full document
7
Immunohistochemical detection of filaggrin in the skin of different species
... the skin barrier. Recent studies have demonstrated that, in humans, muta- tions encoding FLG are a major genetic predisposing factor for atopic ...Furthermore, in immunohistochemical ... See full document
5
Maternal filaggrin mutations increase the risk of atopic dermatitis in children: an effect independent of mutation inheritance.
... mutations in the filaggrin gene (FLG) cause skin barrier deficiency and strongly predispose to atopic dermatitis ...We in- vestigated the 4 most prevalent European FLG ... See full document
16
Epidermal dysfunctions in canine atopic dermatitis: Clinical impacts and therapies
... Canine atopic dermatitis (CAD) is an immune-mediated disease characterized by inflammatory and pruritic ...epidermal barrier failures can facilitate the entry of potential allergens, microorganisms ... See full document
11
Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.
... be in line with results from a previous study where we showed a significant increase in the expression of the TGM1 mRNA and protein in the skin of AD patients sensitized to Mal s compared to ... See full document
5
Update on Atopic Dermatitis
... decades, atopic dermatitis has become a global health ...of atopic dermatitis. In sum, this is a hetero- geneous skin disorder associated with variable morphology, distribution, ... See full document
8
The infant skin barrier
... Infant skin is different from adult in structure, function, and ...the skin barrier is competent at birth in healthy, full-term ...developing skin barrier in ... See full document
19
Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?
... Atopic dermatitis is characterized by a complex network comprising skin barrier dysfunctions, and neural/immune/aller- gic and pruritus ...the barrier is disrupted by ge- netic ... See full document
10
Allergen-Specific Immunotherapy with Monomeric Allergoid in a Mouse Model of Atopic Dermatitis.
... allergen in increasing doses causing tolerance to an allergen is known for a long time [8, 9, 10], however, ASIT is not accepted as a therapeutic strategy [11] for AD patients due to concerns about possible ... See full document
15
Analysis of filaggrin 2 gene polymorphisms in patients with atopic dermatitis,
... located in the granular layer of the epidermis in the granules of ker- ...resulting in the formation of filaggrin monomers having keratin filament aggregation ...properties. Filaggrin degrada- ... See full document
7
Modern child skin care products as a basic treatment in atopic dermatitis
... basic skin care for children with Atopic Dermatitis ...epidermal barrier dysfunction is known to be the leading factor in pathogenesis of atopic dermatitis and it ... See full document
3
Serological identi ication of house dust mite allergens in dogs with atopic dermatitis
... kDa. In another study (Noli et ...detected in the sera of these animals. In the study of McCall et ...allergens in other study (Nut- tal et ...positive skin reactions to puriied group ... See full document
5
Narrowband UV-B phototherapy in childhood atopic dermatitis: efficacy and safety
... Atopic dermatitis (AD) is a common and distressing con- dition characterized by itchy, chronically relapsing inflammatory skin lesions associated with personal or family history of ...15-20% ... See full document
6
Melatonin and Atopic Dermatitis: New Insights in Pathophysiology and its Role in Sleep Disturbance
... quality in patients with atopic ...scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic fac- tor and substance ... See full document
6
Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring.
... identified in several body fluids including serum, breast milk, amniotic fluid and ...role in intercellular ...miRNAs in breast milk are considered to be ...system. In support of the ... See full document
16
Variants in a novel epidermal collagen gene (COL29A1) are associated with atopic dermatitis.
... offspring in both family ...preponderance in AD status among the parents in both ...AD in mothers and ...used in this study, nonparametric linkage and TDT, do not take into account the ... See full document
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