[PDF] Top 20 Synthesis and antimicrobial evaluation of 2-(2-butyl- 4-chloro-1H-imidazol-5-yl-methylene)-substituted-benzofuran-3-ones
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Synthesis and antimicrobial evaluation of 2-(2-butyl- 4-chloro-1H-imidazol-5-yl-methylene)-substituted-benzofuran-3-ones
... oxidation of 3-(4-chloro-1H-imidazol-5-yl)-1-(2-hydroxyphenyl)prop-2-en-1- ones with mercuric(II) acetate in in polyethylene glycol (PEG-400) gave the corresponding ... See full document
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Synthesis and antimicrobial activity of new amino derivatives of pyrano[4’’,3’’:4’,5’]pyrido[3’,2’:4,5]thieno[3,2-d]pyrimidine
... derivative 2, which in turn underwent intramolecular cyclization under the action of potassium hydroxide in ...one 3 (Figure 1). The IR spectrum of compound 3 showed absorption bands ... See full document
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Synthesis, X-ray diffraction study and pharmacological evaluation of 3-amino-4-methylthiophene-2-acylcarbohydrazones
... design of a myriad of bioactive ...design, synthesis, X-ray diffraction study and the pharmacological evaluation of a series of ... See full document
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF DICHOTOMIN A ANALOGS
... roots of Stellaria dichotoma, showed cell growth inhibitory activity 1 and used as folk medicine for ...structures 2-4 . A review of the structures of cyclic peptides exhibiting ... See full document
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Synthesis and antimicrobial activities of 5arylidenethiazolidine2,4dione derivatives
... inactivation of the drug, prevention of the penetration of the target site within the microbe, and alteration of drug target ...development of new derivatives to be used as ... See full document
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Sulfonamide and carbamate derivatives of 6-chloropurine: synthesis, characterization and antimicrobial activity evaluation
... mL of THF: pyridine ...bath and then sodium hydride ...salt of 6-chloropurine (5). The completion of the reaction was confirmed by disappearance of starting material in the ...chlorides ... See full document
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Synthesis and evaluation of antimicrobial activity of halogenated furanones and compounds analogues to nostoclides.
... SYNTHESIS AND EVALUATION OF ANTIMICROBIAL ACTIVITY OF HALOGENATED FURANONES AND COMPOUNDS ANALOGUES TO ...spectrum of biological activity of ... See full document
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MATERIAL AND THE METHoDS Plant material
... peculiarities of essential oils such as volatility, low solubility in water and their complexity, significantly interfere with the results of tests for evaluation of ... See full document
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SYNTHESIS AND ANTIMICROBIAL ACTIVITIES OF NEW PYRAZOLOPYRIDAZINE DERIVATIVES
... field of medicinal chemistry. Pyridazine ring is a part of the structures of a number of drugs available in the market 1 like cadralazine, minaprine, hydralazine, pipofezine, etc (Figure ... See full document
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Design, synthesis and biological evaluation of (E)2(2)quinoxalines, a promising and potent new class of anticancer agents
... majority of the active compounds from the first phase were selected for further evaluation against the four human cancer cell lines: OVCAR-8 (human ovary), SF-295 (glioblastoma), HCT-116 (colon) and ... See full document
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Synthesis and Cytotoxicity Evaluation of a Series of 3-Alkenyl-2-Hydroxy- 1,4-Naphthoquinones Obtained by an Efficient Knoevenagel Condensation
... The 3-alkenyl-2-hydroxy- 1,4-naphthoquinone compound 4j was shown to be the least cytotoxic for all tested cell lines (Table ...11c, and even more cytotoxic than the positive ...10b/11b and ... See full document
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J. Braz. Chem. Soc. vol.18 número3
... novel 2-aroylimimnothiazolidin-4-ones has been ...stability of the two regioisomers 2 and 3 with 2 as the predominant ...simplicity of the experimental procedure ... See full document
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Synthesis, structural characterization and antimicrobial evaluation of some novel piperidin-4-one oxime esters
... reagents and solvents were of reagent grade and used without further ...Completion of reactions was monitored by TLC on silica gel-coated aluminum sheets (Type 60 ...capillaries and are ... See full document
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Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.
... The antimicrobial potency of the synthesized CAM dimers was tested against a panel of Gram- negative and Gram-positive ...gene, and one clinical isolate of Pseudomonas aeruginosa ... See full document
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Cytotoxic evaluation of substituted benzaldehydes
... organic synthesis since it is able to perform a large number of chemical transformations such as the preparation of alcohols, ethers, carboxylic acids, esters and ...bond, and may be ... See full document
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Synthesis of substituted 1,3,5-triazines and toxicity evaluation against Artemia Salina leach.
... 11. Chen, C.; Lin, C.; J. Chromatogr. Sci. 1995, 33, 229. 12. Gokel, G. W.; Durst, H. D.; Synthesis 1976, 168. 13. Reimlinger, N.; Jadot, V. O.;Chem. Ber. 1970, 103, 1954. 14. MacLaughlin, J. L.; Methods in Plant ... See full document
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Synthesis and Antimicrobial Activity of Glycosylated 2-Aryl‑5‑amidinobenzimidazoles
... (HMBC) and correlation spectroscopy (COSY) ...C-20 and aromatic H-16 in the HMBC experiment, which unequivocally confirmed the identity of H-16, registered as a doublet (Figure ...assignment ... See full document
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Synthesis and evaluation of 5-substituted (thio)barbiturates as proteasome inhibitors for cancer therapy
... case of in-patient supply requests and TTAs requests, once the prescriptions have been verified by the pharmacist, an order sheet (appendix XV) is filled with patient’s name, hospital number, the drug, ... See full document
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Synthesis, Characterization and Antimicrobial Activity of Certain Novel Aryl Hydrazone Pyrazoline-5-Ones Containing Thiazole Moiety
... pyrazolines and related heterocycles demonstrate various types of biological ...importance of these compounds lies in the fact that they can be effectively utilized as antibacterial, antifungal, ... See full document
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Synthesis and antifungal evaluation of imines derived from 3-Amino-2-isopropyl-3H-quinazolin-4-one
... One of the more important reason for our interest in 3-aminoquinazolinone 46 (1) relates to the possibility of condensation of the amine group in its structure with more feasibility that ... See full document
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