[PDF] Top 20 Transcriptome overview of Paracoccidioides brasiliensis proteases
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Transcriptome overview of Paracoccidioides brasiliensis proteases
... proteasome of higher eukaryotes is also composed of seven distinct α and β subunits, respectively (Krüger et ...threonine proteases (Groll et al., 1997). The proteolytic activities of the ... See full document
14
Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition
... lack of classic genetic tools for the study of P. brasiliensis, such as DNA-mediated transformation and mod- ulation of gene expression by gene knockout or RNA interfer- ence techniques, the ... See full document
14
Bioinformatics of the Paracoccidioides brasiliensis EST Project
... Felipe, M.S., Andrade, R.V., Petrofeza, S.S., Maranhao, A.Q., Torres, F.A., Albuquerque, P., Arraes, F.B., Arruda, M., Azevedo, M.O., Baptista, A.J., Bataus, L.A., Borges, C.L., Campos, E.G., Cruz, M.R., Daher, B.S., ... See full document
14
Paracoccidioides brasiliensis induces secretion of IL-6 and IL-8 by lung epithelial cells. Modulation of host cytokine levels by fungal proteases
... importance of MAPKs on cytokine secretion during interaction of A549 cells with live ...none of the inhibitors (PD98059, SB203580 and SP600125) were able to reduce IL-6 and IL-8 levels in these ... See full document
9
Screening for glycosylphosphatidylinositol- anchored proteins in the Paracoccidioides brasiliensis transcriptome
... capable of removing the GPI anchors from proteins have been reported (Low and Saltiel, ...P. brasiliensis, Heise et al. (1995) reported the detection of a potent PLC capable of selectively ... See full document
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NLRP3 Inflammasome Activation by Paracoccidioides brasiliensis
... cysteine-aspartic proteases, mainly caspase-1, we selectively inhibited this protease using the aldehyde derivative AC-Y- VAD-CHO in BMDCs that were infected with yeast ...processing of IL-1b in DCs ... See full document
11
Transcriptome Profile of the Response of Paracoccidioides spp. to a Camphene Thiosemicarbazide Derivative.
... silencing of SOD1 in ...genome of P. brasiliensis yeast cells via ATMT in order to silence the SOD1 ...length of 85 bp. This AS oligonucleotide was placed under the control of the ... See full document
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Análise estrutural e de expressão do gene pacC de Paracoccidioides brasiliensis
... FELIPE, M. S.; ANDRADE, R. V.; PETROFEZA, S. S.; MARANHAO, A. Q.; TORRES, F. A.; ALBUQUERQUE, P.; ARRAES, F. B.; ARRUDA, M.; AZEVEDO, M. O.; BAPTISTA, A. J.; BATAUS, L. A.; BORGES, C. L.; CAMPOS, E. G.; CRUZ, M. R.; ... See full document
129
Caracterização e análise da expressão de microRNAs-like de Paracoccidioides brasiliensis
... species of the Paracoccidioides complex, transcriptional data also demonstrated genes that are expressed at each specific stage of these ...expression of genes such that one encoding for ... See full document
231
Therapeutic targets in Paracoccidioides brasiliensis: post-transcriptome perspectives
... transfer of myristate from Co-enzyme A to the amino-terminal Gly residue of a number of cellular proteins involved in signal transduction pathways (Nagarajan et ...viability of the several ... See full document
20
Overview and perspectives on the transcriptome of Paracoccidioides brasiliensis
... Detection of glycosylp- hosphatidylinositol (GPI) membrane anchors in proteins of ...P. brasiliensis was described for the first time in 1995 ...P. brasiliensis transcriptome analysis ... See full document
10
The cell wall of Paracoccidioides brasiliensis: insights from its transcriptome
... P. brasiliensis, PbFks1p seems to assemble the phosphorylated glucan polymer and extrude it out of the membrane simultaneously, since the PTS-HPr (phosphotransferase sys- tem-phosphoryl carrier protein) ... See full document
17
THE POWER OF THE SMALL: THE EXAMPLE OF Paracoccidioides brasiliensis CONIDIA
... decrease of both thin reticulin and collagen fibers ...deposition of these proteins, which are considered fibrosis indicators, was reduced to normal levels, as seen in the control uninfected mice, and ... See full document
6
VACINAÇÃO COM A PROTEÍNA DE CHOQUE TÉRMICO HSP60 INDUZ RESPOSTA IMUNE PROTETORA CONTRA A INFECÇÃO PULMONAR INDUZIDA PELO Paracoccidioides brasiliensis E TRANSFORMAÇÃO EM Paracoccidioides brasiliensis
... target of T cell mediated immunity and a protective vaccine in experimental pulmonary histoplasmosis (18, ...models of infection with intracellular parasites. Given the high level of evolutionary ... See full document
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Peptideos derivados da gp43 de Paracoccidioides brasiliensis inibem a fagocitose
... component of P. brasiliensis is a 43-kDa secreted high- mannose glycoprotein ...100% of patient´s sera [2] being, like other fungal components, a ligand to concanavalin ...mechanisms of ... See full document
126
Resultado tardio da infecção isolada no quadril por Paracoccidioides brasiliensis
... reduction of joint space and flattening of the upper region of femoral head (Figure ...infiltration of adjacent soft tissues, joint edema and capsule ...biopsy of the injury was ... See full document
3
DOSE RESPONSE EFFECT OF Paracoccidioides brasiliensis IN AN EXPERIMENTAL MODEL OF ARTHRITIS
... de P. brasiliensis (Pb18). Os fungos foram injetados em 50 µL de solução salina em tampão fosfatado (PBS) diretamente na articulação do joelho dos animais. Os seguintes parâmetros foram analisados neste trabalho: ... See full document
6
Papel do receptor NOD2 no controle da infecção por Paracoccidioides brasiliensis
... As micoses consistem em infecções causadas por fungos, e podem ser classificadas segundo o local de infecção: micoses superficiais, cutâneas, subcutâneas e sistêmicas (RICHARDSON; WARNOCK, 2012). Tendo como porta de ... See full document
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Caracterização estrutural da forma recombinante da proteína Pb27 de Paracoccidioides brasiliensis
... nativa através de sua purificação por afinidade utilizando anticorpos anti-Pb27 obtidos da imunização de coelho serão realizadas. O estudo da estrutura tridimensional desta proteína permitirá um entendimento mais ... See full document
19
Caracterização da N-acetil-ß-D-glicosaminidase de Paracoccidioides brasiliensis
... P. brasiliensis tenha sido isolado no solo, no trato digestivo e nas fezes de alguns animais, como morcegos frutívoros, tatus e pingüins, seu habitat natural ainda permanece desconhecido (Lacaz et ... See full document
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