Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages.

irf8 null mutants lack microglia during development and are viable Morpholino knockdown studies have indicated that irf8 plays a role in macrophage develop- ment in zebrafish [ 17

To further our understanding of the mechanisms by which HIV-1 co- infection impairs immunity to malaria in pregnancy, we investigated the effects of in vitro HIV-1 infection

VCAM-1, ICAM-1 and E-selectin in the aorta and expression of TF, IL-1 β , IL-6 and TNF- α in peritoneal macrophages of mice were also significantly attenuated by PDTC and/or Curcu-

The PSC developed by the IRF studies was developed in an effort to improve the quality of the patient rehabilitation by decreasing the occurrence of the acute

To determine the role of PDE8A in HIV-1 replication in macrophages, we analyzed the effect of PDE8A knockdown by shRNAs on the HIV-1 replication cycle in these cells.. We selected

To further investigate the pathway involved in this regulation of IL-7 expression, LoVo cells were treated with KGF (150 ng/ml) for 0 h, 2 h, 3 h and 6 h, and IRF-1, IRF-2

To examine the effects of HIV-1 Nef expression on viral replication and transmission in a physiologically relevant system, HIV-1 infection of activated PBLs and DC-mediated

Total pathological severity scoring of lungs, liver and spleen indicated a disease in Irf3 2 / 2 mice consistent with bacterial sepsis on day 3 post-infection, with a large degree