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Characterization of the Effect of Drug-Drug Interaction on Protein Binding in Concurrent Administration of Sulfamethoxazol and Diclofenac Sodium Using Bovine Serum Albumin

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Academic year: 2017

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Figure 2. Scatchard plot of diclofenac sodium at pH 7.4 and 40 °C  D f   is  the  free  drug  concentration  and  r  is  the  ratio  of  molar  concentration  of  bound  drug  and  protein,  K 1 =  High  affinity  association  constant,  n 1 =  Number  of
Table 1.  Effect of sulfamethoxazole on diclofenac sodium bound to BSA
Table 2.  Effect of diclofenac sodium on sulfamethoxazole bound to BSA

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