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Some aspects of оesophagus morphogenesis at the early stages of prenatal ontogenesis in human being

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Marchuk O.F.Some aspects of esophagus morphogenesis at the early stages of prenatal ontogenesis in human being. Summary. The peculiarities of esophagus morphogenesis and topography formation in embryos and prefetuses of human being by the complex of morphological methods h ve been studied. Topographical differences in germ of esophagus and respiratory tube was set. In embryos of 4.5-5.0 mm PCL the process of diaphragm formation was observed, which was com-plete in prefetuses of 18.0-19.0 mm PCL. In embryos of 9.0-9.5 mm PCL the enlarge of circular layer of esophagus muscular membrane was observed; in embryos of 18.0-19.0 mm PCL the longitudinal layer was enlarged. Infurtherdevelopment a circular layer thickness was in prevalence due to the thickness of longitudinal layer along all length of esophagus. As a result of condensing interorganic layers of mesenchyma more close correlative intercommunications between esophagus, trachea, thoracic aorta, vagus nerves and serous membranes was set. At the end of prefetuses period the process of recanalisation of esophagus was completed.

Key words: esophagus, embryo, prefetus, human being.

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Katzka D.A. Congenital esophageal stenosis in adults // Am. J. Gastroenterol.- 2000.– Vol.95, №1.– P. 32-36.

Malinger G., LevineA., Rotmensch S. The fetal

esophagus: anatomical and physiological ultrasono-graphic characterization using a highresolution lin-ear transducer // J. Ultrasound Obstet. Gynecol.– 2000.– Vol.24, №5.– P.500-505.

Martener L. The vagus and recurrent laryngeal nerves in experimental congenital diaphragmatic hernia // J. Pediatr. Surg. Int.– 2004.– Vol.20.– P.253-257.

Tobin R.W. Esophageal rings, webs and diver-ticula // J. Clin. Gastroenterol.- 1998.– Vol.27, №4.– P.285-295.

(6)

__________________________________________________________________________________ І • 2008 • ІI • №1

79 atresia: what has changed in the last 3 decades? // J.

Pediatr. Surg. Int.– 2004.– Vol.520, №10.– P.768-772.

Wei J.L., Rodeberg D., Thompson D.M.

Tra-cheal agenesis with anomalies found in both VAC-TERL and TACRD associations // Int. J. Pediatr. Otorhino-laryngol.– 2003.– Vol.67, №9.– P.1013-1017.

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