Protein-protein docking with F(2)Dock 2.0 and GB-rerank.

xi The work described in this thesis aims to study the utilization of paramagnetic probes in the study of protein-protein interactions (transient complexes) and the development

Ar- bitrary atoms of thrombin active site which were selec- ted for the nearest atom filters and center of mass filter are shown in Fig 1.. Results

The superior performance of DMP323, when compared to the others ligands, may be due to a minor de- pendence among its dihedral angles and to the fact that its correct conformation

Since the enantioselective complexes which could not be stripped at once, formed by chiral carrier with two enantiomer, only could be stripped by means of diffusing through the

An alternative is that proteins attach to each other as they are being translated in the ribosome (called cotranslational assem- bly). To investigate if cells use

Both the GST fusion protein and purified DFR minus the GST tag could be stored at 2 80uC for several months without loss of enzyme activity and demonstrated identical

While this analysis is able to determine bona fide protein interactions and to separate the subunits of the two complexes, on stable complexes like Rpd3 all probabilities in

The computation of modularity using network projections as well as the bipartite graph itself suggests that protein complexes as well as drug networks are not random networks