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Cysteine proteinases and cystatins

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(13)

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% )! $ &'( ! 4 % ,,. 6:2+6:8! 7H !0 4 )!0 ) C!0 C )!0 4 ; +. D 4 4!$ 8(! , # # ! % 5 % ! -. + 2 ! 7 <! 9! >!0 4 <! ?! 4 ! ! <! $ &8( 4 + 4)+ # ' ! ! $ .% 5 % ! ,= 8/8+882! 7 ! 4! $ 222( UT UT # W # $ ; , (! < ? B 1 = % % F1% ! 7 =! 9!0 4 - 3! ! D ! ! $ '( . # " # # ! .% 3 0- ! .= $ 2( & 6+ 22! 1! ! $ 222( . UT W Y 5 $ (! < ? B 1 = % % F1% ! <!0 4 +< 1!0 = 9! 4 =! $ &( ! 5 % ! -? $/( 6:+ ' ! 1 " %! 5! ! 3! $ '( B ! 5 0 ' $- ! ,.. '/ +'&/! 1 ! ! $ 2(! # = . 5 . ! 6 % % 0- 0 % ,?' :+' ! 1 4! %!0 9 D! ! < < <! ! $ &( # ! 0- 0 -! .> :8+/6! 4 B!0 . 4!0 4 C! 7 C! $ ( .. # " " # ! % ( 0- % % ( ! +;/ 282+ 28:! 4 %!0 . C!0 ? ;! C ! $ 2( < * 5% ! " 6 ! +? $ ( // &! 4 <! ! $ &2( . # 4 ! 0- ! .? //+ 82! 4 =!0 - !0 # <!0 = ## ! ! 3! $ &/( ) "+< -* # ! 0 % .! ,-. ' +'6'! 4 ! ! I +B 3! $ ( # " ( 0 $B!( 7 , $ !( $ (! ( % 0 % 0- ! >> $ ( : +:66! 4 - 1! )! < - 9! 9! $ &6( 9 , # # " 5 4 2 $9 4 (! ' % ' ! +, 8&8+8 !

(14)

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