Comparative bioequivalence study of meloxicam drugs

ISSN: 1804-1884 (Print) 1805-5014 (Online) Volume 5, 2011, pp. 112-114

© 2011 Prague Development Center

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EKUT KARIEVA, KH_АLIDAYUNUSOVA

Tashkent Pharmaceutical Institute Uzbekistan

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© 2011 Prague Development Center

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TABLE 1.FINDINGS OF CONVERGENCE AND DIFFERENCE FACTORS FOR MELOXICAM DRUGS

Time, min

Data for tablets “Melbek” and meloxicam tablets Data for tablets “Melbek” and meloxicam capsules Mean values of number of active

ingredient dissolved into the medium, %

Values of the factors

Mean values of number of active ingredient dissolved into the medium,

%

Values of the factors

Tablets “Melbek”

Meloxicam tablets

Convergence factor

Differrence factor

Tablets “Melbek” Meloxicam tablets

Convergence factor

Differrence factor 5 29.1±2.2 25.3±2.4

76.0 4.3

29.1±2.2 18.0±3.4

52.0 11.3

15 54.3±2.8 49.8±3.3 54.3±2.8 40.1±3.8

30 74.3±3.7 73.1±2.7 74.3±3.7 72.5±2.9

45 83.9±3.1 84.8±2.8 83.9±3.1 84.1±3.5

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