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Gene therapy: development of a new nanocarrier system for mitochondrial gene therapy

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Academic year: 2021

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Figure 1. Human Mitochondrial DNA. Circular double-stranded molecule of 16,568 (bp) in length  consisting predominantly of coding DNA that codes for 13 polypeptides, 2 ribosomal RNAs (rRNAs), and
Figure 3. Electron transport chain of mitochondria. The function of the electron transport chain is to  produce a transmembrane proton electrochemical gradient as a result of the redox reactions ending
Figure 4. Mitochondrial sources of ROS and mitochondrial ROS targets. ROS generators (red) and ROS  targets (yellow) are present all over mitochondria
Figure 5. Mitochondrial Ca transport pathways. A) Mitochondrial Ca uptake and mechanisms and  pathways located at the IMM
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