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Editorial

169

Nitrini In the September 2016 issue Dement Neuropsychol 2016 September;10(3):169

Editorial

In the September 2016 issue

In this issue we are publishing one review, eight original papers, four case reports and one history note.

Studart-Neto and Nitrini reviewedthe state-of-the-art con-cerning subjective cognitive decline in the elderly. he dark boundaries between the impact of normal aging and early signs of Alzheimer’s disease (AD) may be illuminated through novel methods, including biomarkers, and neuroimaging advances.

Fukushima et al. systematically reviewed studies on the ef-fects of cognitive stimulation on the neuropsychiatric symp-toms in AD, mainly apathy, depression and anxiety. he au-thors concluded that cognitive stimulation programs are an efective therapeutic alternative for these otherwise diicult-to-manage symptoms of AD.

Holanda and Almondes performeda systematic review to evaluate the role of age-related sleep changes in executive functions (EF). Several markers of poor sleep quality were as-sociated with worse EF scores.

Mota et al. investigated the association of low education with delirium in adults at an Emergency Department over a 6-month period. Delirium was more frequent in the aged and in low-educated individuals.

Schelp et al. evaluated the relationships between episodic memory, age, and education in patients with Parkinson Dis-ease. Patients with episodic memory impairment were older and had low performance on other screening tests, support-ing reports of a wide spectrum of neuropsychological perfor-mance impairment in PD.

Ortiz et al. investigated the presence of speech disorders in PD, particularly sensorimotor disorders of programming, in addition to execution disorders. As a group, patients with PD had worse performance on all sensorimotor speech tasks.

Roman et al. translated and adapted the Memory Binding Test (MBT) to estimate its diagnostic accuracy as a tool for early detection of amnestic mild cognitive impairment (aMCI) in Argentina. hey concluded that the Argentinian version of the MBT is a useful tool for the detection of aMCI.

Beber et al. compared performances on two clock draw-ing tests (CDT) of patients with MCI or dementia. One CDT wasfreely-drawn whereas the other was an incomplete-copy where only the hands had to be drawn. he free-drawn CDT version was more sensitive for detecting mild/early cognitive impairment.

Mantovani-Nagaoka et al. evaluated the performance of healthy subjects on a limb apraxia battery and analysed the inluence of gender, age, and education on it. hey found an important inluence of education level on the outcome of limb apraxia tests.

Passos et al. reported a mother and her only daughter with incapacitating behavioral manifestations of frontal lobe dysfunction associated with epilepsy, and discussed the likeli-hood of a hitherto unreported genetic condition.

Brucki et al. reported the case of a 63-year-old woman with an arteriovenous malformation (AVM) associated with pro-gressive dementia. he plausible causal relationship between AVM and dementia is discussed.

Martinelli et al. reported a case of a 79-year-old woman with musical hallucination (hearing a sung National anthem) without hearing loss, cognitive impairment or known psychi-atric condition. Neuroleptics led to complete remission.

Costa et al. reporteda case ofpantothenate kinase-asso-ciated neurodegeneration (PKAN) that presented with typi-cal symptoms of Tourette syndrome. he severity and poor response to treatment led to further investigation and to the diagnosis of PKAN as a secondary cause of Tourettism.

Engelhardt in this history note outlined the discoveries of

François Magendie and Hubert von Luschka, who described the median and lateral openings of the 4th ventricle,

subse-quently named after them. he author also revealed that even after these discoveries, the existence of these holes was ques-tioned by many anatomists.

Ricardo Nitrini

Editor-in-Chief

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