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FELIPE-SILVA A ET AL.

284 REV ASSOC MED BRAS 2014; 60(4):284-285

ACCREDITATION

Update on angle-closure glaucoma: diagnosis

A

TUALIZAÇÃO EM GLAUCOMA DE ÂNGULO FECHADO

:

DIAGNÓSTICO

JAIR GIAMPANI JR, WANDERLEY M. BERNARDOAND RICARDO SIMÕES

http://dx.doi.org/10.1590/1806-9282.60.04.002

1. What is the importance of gonioscopy in the di-agnosis of patients with angle-closure glaucoma?

a. It allows the extension of a given open angle to be

es-tablished.

b. This is the most relevant examination for the

classi-fication of glaucoma.

c. Excessive pressure exerted on the lens can reduce the

opening angle of the anterior chamber.

d. It does not allow differentiation between the

apposi-tion of the iris and the true goniosynechiae.

2. What is the role of UBM (ultrasound biomicros-copy) in the diagnosis of patients with angle-clo-suer glaucoma?

a. The disadvantage is the impossibility of assessing

ret-ro-iridian structures.

b. The main advantage is the immersion of the

ultra-sound probe.

c. The apposition of the iris to the outer wall of the

ca-merular sinus has been more frequently detected by UBM than gonioscopy.

d. UBM can replace the semi-quantitative analysis of

go-nioscopy.

3. What is the role of AS-OCT (anterior segment op-tical coherence tomography) in the diagnosis of patients with angle-closures glaucoma?

a. The main advantage is the possibility of assessing

ret-ro-iridian structures.

b. It is the traditional method and reference for the

di-agnosis of angle-closure glaucoma.

c. AS-OCT does not allow assessment of iris profile.

d. AS-OCT is useful for quantitative evaluation of the

camerular sinus.

4. Can AS-OCT replace gonioscopy?

a. The sensitivity of OCT (98%) to detect closed angles

is always greater.

b. There is greater concordance between the two

meth-ods in detecting closed angles in the upper quadrants.

c. OCT can replace the semi-quantitative analysis of

go-nioscopy.

d. The specificity of OCT (98%) to detect closed angles

is always greater.

5. What is the validity of the prone-position test in dark room in the diagnosis of angle-closure glau-coma?

a. Definitive diagnosis of chronic angle-closure

glauco-ma.

b. Identification of “congestive glaucoma,” with

posi-tivity in 98% of cases.

c. Checking the probability of angle closure when there

is IOP elevation.

d. Diagnosis of angle closure, with positivity in 98% of

cases.

A

NSWERS TO CLINICAL SCENARIO

:

UPDATE ON POLYCYSTIC KIDNEY DISEASE

(

HEREDITARY

):

GE

-NETIC DIAGNOSIS AND COUNSELING

[

PUBLISHED IN

2014; 60(3)]

1. In prenatal and neonatal context, is ultrasonog-raphy sufficient to confirm the clinical diagnosis of autonomal recessive polycystic kidney disease (ARPKD)?

Renal ultrasound abnormalities are detectable from

the 13th week of pregnancy when the diagnosis was

previously established in an affected sibling.

(Alter-native D)

2. In the context of an adult, if the result of the ul-trasound examination is inconclusive, does the molecular test allow reaching a definitive conclu-sion?

The type and position of mutations in the PKHD1 gene provide information about the prognosis of the

disease. (Alternative C)

3. Does ultrasound examination allow confirming the clinical diagnosis of autosomal dominant pol-ycystic kidney disease. (ADPKD)?

In patients aged 15 to 29 years with 3 or more unilat-eral or bilatunilat-eral cysts, the sensitivity is 69.5% and

(2)

UPDATEONANGLE-CLOSUREGLAUCOMA: DIAGNOSIS

REV ASSOC MED BRAS 2014; 60(4):284-285 285

4. What are the advantages and disadvantages of

in-direct versus direct aproaches in molecular testing

for ADPKD?

Haplotype analysis is quick, simple and inexpensive.

(Alternative B)

5. What is the role of molecular testing for genetic counseling of a couple or family that carries AD-PKD?

Molecular tests are the only investigation that can pro-vide predictive information about ADPKD in individ-uals before clinical signs and symptoms develop.

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