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Molecular determinants of the response to malaria therapeutics

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Academic year: 2021

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Figure 1 – Non-genetic parameters influencing the variation in drug effect.
Figure 2 – Life cycle of P. falciparum and typical stages of action of antimalarial drugs  (adapted from http://www–ermm.cbcu.cam.ac.uk)
Figure 3 – Structures of the main antimalarial drugs used in first-line treatments  (structures from www.genome.jp/kegg/, Kyoto Encyclopedia of Genes and Genomes)
Table 1 – Pharmacological properties of the antimalarials in widespread use * .
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