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A Role for Na

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Figure 2. Candidate protein depletion and effects on melanosome distribution. Melan-INK4a cells were treated with siRNA pools for NT, Pmel17, GPNMB, Anxa2, ATP1a1 (A+B) or individual siRNAs for NT, ATP1a1 (1–4) or Mlph for 72 h (C+D)
Figure 3. Rab5a-positive vesicle distribution is unaffected following ATP1a1 depletion
Figure 4. GST-ATP1a1-M4M5 interacts directly with Rab27a. GST or GST-ATP1a1-M4M5 was incubated with A) melan-INK4a cell lysates, B) his 6 -Rab27a WT or his 6 -Rab5a WT
Figure 7. Rab38 localisation to melanosomes is unaffected following ATP1a1 depletion. Melan-INK4a cells were treated with either NT or ATP1a1 siRNA and cultured for 72 h

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