Anti-tumor
Anti-tumor effects of the peptide TMTP1-GG-D(KLAKLAK)(2) on highly metastatic cancers.
... Recently, we identified a 5-amino acid peptide, TMTP1, which bound to a series of highly metastatic cancer cell lines in vitro and in vivo, particularly those from atypical liver micrometasteses that contained small ...
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Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine.
... E7. Tumor preventive assays, based on the engraftment of TC-1 cells in mice, showed that the E6E7 multi-epitope protein induced a full preventive anti-tumor protection in wild-type mice, as well as ...
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Improved local and systemic anti-tumor efficacy for irreversible electroporation in immunocompetent versus immunodeficient mice.
... local anti-tumor response in immunocompetent (IC) BALB/c versus immunodeficient (ID) nude mice, including the potential for a systemic protective effect against ...on tumor burden and the ...
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A Narrative Review on Anti-Tumor Necrosis Factor α Therapies in Inflammatory Bowel Disease During Pregnancy: Immunoglobulin Placental Translocation and its Impact
... Discussion: Anti-tumor necrosis factor α agents are efficient treatments for moderate-to-severe inflammatory bowel disease and may ensure remission during ...disease. Anti-tumor necrosis ...
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Anti-Tumor Effects of Second Generation β-Hydroxylase Inhibitors on Cholangiocarcinoma Development and Progression.
... Cholangiocarcinoma (CCA) has a poor prognosis due to widespread intrahepatic spread. Aspartate β-hydroxylase (ASPH) is a transmembrane protein and catalyzes the hydroxyl- ation of aspartyl and asparaginyl residues in ...
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Pyruvate induces transient tumor hypoxia by enhancing mitochondrial oxygen consumption and potentiates the anti-tumor effect of a hypoxia-activated prodrug TH-302.
... hypoxic tumor microenvironment, has generated a series of anti-tumor compounds generally classified as hypoxia-activated prodrugs (HAPs) since their original description in 1980 ...causing ...
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Anti-tumor immunity induced by a novel nanoparticulate vaccine : a mechanistic approach
... effective tumor regression ...from tumor cells by mounting robust innate and adaptive immune ...However, tumor is able to induce sophisticated immune escape mechanisms where both cancer cells and ...
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Activation of anti-tumor immune response and reduction of regulatory T cells with Mycobacterium indicus pranii (MIP) therapy in tumor bearing mice.
... Since 1882, when Coley used a bacterial preparation (Coley toxins) to treat sarcomas, there has been evidence that bacterial products can beneficially affect the course of several cancers. BCG has been used extensively ...
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MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
... Since all of the 3 valid microRNAs showed negative effects on the expression of p38, we in- ferred that they were likely to act as dendritic cell regulators to affect anti-tumor responses. Previous data had ...
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Mathematical modeling of interleukin-27 induction of anti-tumor T cells response.
... Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon- c secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer ...
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Retrospective cohort study of anti-tumor necrosis factor agent use in a veteran population
... as anti-TNF agents, for Crohn’s disease have provided clinically meaningful improvement in patient reported outcomes while maintaining remission (Ford et ...of anti-TNF therapy has shifted costs from ...
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Regulation of cysteinyl leukotriene receptor 2 expression--a potential anti-tumor mechanism.
... Prolonged inflammation is known to increase the risk of developing cancer [1,2]. It has been estimated that 15% of all cancers can be accredited to infectious agents [3]. Tumor microenvironment has often been ...
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In silico experimentation of glioma microenvironment development and anti-tumor therapy.
... Although much is known about the identities and biochemical activities of signaling molecules in the glioma microenvironment [1,2,3,4,5,44,45], how these mediators coordinate and function collectively at the systems ...
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Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia.
... WEHI-3 tumor cells by induction of apoptosis via interruption of an oncogenic transcription factor, pSTAT3 which was overexpressed in primary human tumors included AML as well as the WEHI-3 cells ...the ...
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Correction: Adverse Events of Anti-Tumor Necrosis Factor α Therapy in Ankylosing Spondylitis.
... Creative Commons Attribution License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited..[r] ...
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The novel fusion proteins, GnRH-p53 and GnRHIII-p53, expression and their anti-tumor effect.
... goat anti- mouse IgG conjugated to horseradish peroxidase (Jackson, America) with 1:1,000 dilution at 37°C for 45 min, the band was developed using ECL (Applygen Technologies ...
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Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity.
... have anti-proliferative properties ...different tumor cells with increasing concentrations of curcumin for 24 h and measured changes in cell proliferation applying WST-1 assay ...strong anti- ...
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Rev. Bras. Reumatol. vol.53 número1 en v53n1a10
... human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA ...
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Apoptosis inducing capacity of Holothuria arenicola in CT26 colon carcinoma cells in vitro and in vivo
... implanted tumor growth After elucidate in vitro cytotoxic effect of sea cucumber extract, we examined anti‐tumor effect in colon cancer mouse ...reduced tumor size and volume dose dependently ...
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Artrite reumatóide: diagnóstico e tratamento.
... Adalimumab, a full y human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the A[r] ...
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