Aplastic anemia
A retrospective comparison of cyclophosphamide plus antithymocyte globulin with cyclophosphamide plus busulfan as the conditioning regimen for severe aplastic anemia
... Allogeneic hematopoietic stem cell transplantation (AHSCT) is the treatment of choice for young patients with severe aplastic anemia (SAA). The association of antithymocyte globulin (ATG) and ...
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Differential gene expression profile associated with the abnormality of bone marrow mesenchymal stem cells in aplastic anemia.
... categories of cell cycle, proliferation, apoptosis, hematopoietic cell lineage and immune response. A number of genes involved in the signal pathways for cell cycle (SMAD3, ATM, CCNB1, CDC2, YWHAZ, ORC5L, CDC20, CCNA2, ...
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First-line matched related donor hematopoietic stem cell transplantation compared to immunosuppressive therapy in acquired severe aplastic anemia.
... severe aplastic anemia (SAA) is a rare [1] and potentially fatal disease which is characterized by hypocellular bone marrow and pancytopenia, and mainly affects young ...
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Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia
... The use of antithymocyte globulin as a single therapy or in combination with cyclosporinandcorticosteroidshaschanged thenaturalhistoryofsevereaplasticanemia ...
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The clinical and immune characteristics of patients with hepatitis-associated aplastic anemia in China.
... severe aplastic anemia (VSAA) was diagnosed in the cases SAA with the neutrophil count , ...anaplastic anemia (AA) (diagnosed by familial history, Mitomycin test and genetic tests), clonal diseases ...
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Long-term outcome of 25 children and adolescents with severe aplastic anemia treated with antithymocyte globulin
... Twenty-five patients with SAA, less than 20 years of age, were treated with ATG at the University Hospital, Federal University of Parana, Brazil (Table 1). Patients, or their legal representatives, signed an informed ...
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Characteristics of two conditioning regimens cyclophosphamide plus antithymocyte globulin versus cyclophosphamide plus busulfan in allogeneic stem cell transplantation for severe aplastic anemia
... severe aplastic anemia condi- tioned with 200 mg/kg of cyclophosphamide plus 90 mg/kg of horse antithymocyte globulin (ATG) in 17 patients and 120 mg/kg of cyclophosphamide plus 12 mg/kg of busulfan (Bu) in ...
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Late chimerical status after bone marrow transplantation in severe aplastic anemia according to two different preparatory regimens
... Multivari- ate analysis showed that chimerism >90% is associated with the cyclophosphamide plus busulfan conditioning ( p -value < 0.001) and higher number of infused cells ( p -va[r] ...
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Rev. Bras. Hematol. Hemoter. vol.35 número5
... Aplastic anemia (AA) is a potentially fatal bone marrow failure syndrome in which hematopoietic precursor cells are replaced by fat, resulting in ...
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Rev. Bras. Hematol. Hemoter. vol.30 número4
... Allogeneic bone marrow transplantation for severe aplastic anemia patients with risk factors poor prognosis: is fludarabine a requirement. Rev[r] ...
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Rev. Bras. Hematol. Hemoter. vol.29 número4
... The causes of acquired aplastic anemia (AAA) include immunologic mechanisms and oxidative DNA damage. Glutathione S-Transferase (GST) plays an important role in detoxification. In humans, GST genes encode ...
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Rev. Bras. Hematol. Hemoter. vol.34 número2
... the aplastic anemia features and the subsequent overt development of acute lymphoblastic leukemia has not been ...of aplastic anemia confirmed by bone marrow aspirate and bone marrow biopsy ...
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Rev. Bras. Hematol. Hemoter. vol.33 número6
... severe aplastic anemia with antilymphocyte globulin, cyclosporine and two different granulocyte colony-stimulating factors regimens: a GITMO prospective randomized ...
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Anemia aplásica adquirida e anemia de Fanconi - Diretrizes Brasileiras em Transplante de Células-Tronco Hematopoéticas .
... 22. Schrezenmeier H, Passweg JR, Marsh JC, Bacigalupo A, Bredeson CN, Bullorsky E, et al. Worse outcome and more chronic GVHD with peripheral blood progenitor cells than bone marrow in HLA- matched sibling donor ...
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Sao Paulo Med. J. vol.123 número3
... The LATIN study (Incidence of aplastic anemia and agranulocytosisinLatinAmerica)isaLatinAmericanmulti- centerstudytoestimatetheincidenceofaplasticanemiaand agra[r] ...
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Einstein (São Paulo) vol.9 número2
... severe aplastic anemia has markedly improved in the past four decades due to advances in stem cell transplantation, immunosuppressive therapies and supportive ...severe aplastic anemia, and ...
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Sao Paulo Med. J. vol.117 número4
... in aplastic anemia, the sTfR levels are sig nificantly lo wer than in patients with iro n deficiency anemia, hemo lytic anemia o r in no rmal ...
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Arq. NeuroPsiquiatr. vol.59 número3B
... ABSTRACT - Reversible posterior leucoencephalopathy syndrome (RPLS) has previously been described in patients who have renal insufficiency, eclampsia, hypertensive encephalopathy and patients receiving immunosuppressive ...
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Tratamento atual da anemia aplástica adquirida grave.
... Severe Aplastic Anemia Working Party of the European Group for Blood and Marrow ...severe aplastic anemia: a report from the EBMT-SAA Working ...
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Rev. Bras. Hematol. Hemoter. vol.30 número4
... Hematopoietic progenitor cell transplantation from HLA-identical sibling donors cures 70-90% of Severe Aplastic Anemia (sAA) patients. Older age, heavy exposure to transfusions, immunosuppression treatment ...
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