Apoptosis induction
A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells
... its apoptosis induction action in human colon carcinoma HCT116 ...the apoptosis induced by the complex, indicating cell death by apoptosis through caspase-dependent and mitochondrial intrinsic ...
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Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors.
... mg/ml. Apoptosis induction was assessed by propidium iodide staining and fluorescence-activated cell sorting of cells with a subdiploid (G,2N) DNA ...and apoptosis was determined as in ...
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Growth inhibition of human gynecologic and colon cancer cells by Phyllanthus watsonii through apoptosis induction.
... DNA Fragmentation Analysis by Agarose Electrophoresis Cells were treated in the presence or absence of PW-M, PW- H, PW-E and PPWH-7 (1.0, 10.0 and 100.0 mg/mL) for 48 hours, then harvested by using 500 ml lyses buffer ...
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The effects of hesperetin on apoptosis induction and inhibition of cell proliferation in the prostate cancer PC3 cells
... tioxidant, anti-inflammatory, and lipid lowering effects (10). Hesperetin has also been shown to act as a neuro- protective compound (11) and some studies are indicative of hesperetin neuroprotective properties against ...
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In vitro cytotoxic effects and apoptosis induction by a methanol leaf extract of carob tree (Ceratonia siliqua L.)
... capacity (Kwon et al., 2006; Gonçalves et al., 2010; Lee and Park, 2010). As shown in Table 4, the incubation of HeLa cells with the extract at 200 or 400 µg/ml for both periods of incubation, resulted in the appearance ...
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Apoptosis Induction by E2F Decoy DNA of the Prostate Cancer Cell Line
... and apoptosis of androgen-independent prostate cancer cell line PC-3M the binding specificity of the E2F decoy DNA to the PC-3M nuclear protein was detected by electrophoretic mobility shift assay ...induced ...
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Primary mechanism of apoptosis induction in a leukemia cell line by fraction FA-2-b-ß prepared from the mushroom Agaricus blazei Murill
... inducing apoptosis will go through the caspase system ...for apoptosis in many cells ...the apoptosis cascade, when caspase-9 is acti- vated, it will stimulate caspase-3 expression and lead to ...
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Apoptosis and asthma in the elderly
... to apoptosis induction seem to be a general feature of all T cells in the ...elderly. Apoptosis is involved in many changes which are characteristics of immunosenescence ...the apoptosis ...
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Ru(II)-thymine complex causes cell growth inhibition and induction of caspase-mediated apoptosis in human promyelocytic leukemia HL-60 cells.
... 5. Costa, C.O.D.; Araujo-Neto, J.H.; Baliza, I.R.S.; Dias, R.B.; Valverde, L.F.; Vidal, M.T.A.; Sales, C.B.; Rocha, C.A.G.; Moreira, D.R.M.; Soares, M.B.P.; et al. Novel piplartine-containing ruthenium complexes: ...
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Anti-Tumor Effect of Pinus massoniana Bark Proanthocyanidins on Ovarian Cancer through Induction of Cell Apoptosis and Inhibition of Cell Migration.
... cells. Apoptosis plays a very important role in eliminating mutated or hyper-growing tumor cells ...via apoptosis induction ...induce apoptosis in human cervical cancer Hela cells, human ...
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Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation.
... To provide evidence that the autophagy-inducing effect of this small molecule compound was not restricted to colorectal carcinoma cell line, LC3II formation was assessed in 9 other human cancer cell lines of varied ...
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Induction of apoptosis and antiproliferative activity of naringenin in human epidermoid carcinoma cell through ROS generation and cell cycle arrest.
... The accumulation of free radical mediated damage may be a possible mechanism of cancer development [31]. Excessive ROS production can lead to oxidation of macromolecules and play an important role in mtDNA mutations, ...
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Inhibitory and Cytotoxic Activities of Salvia Officinalis L. Extract on Human Lymphoma and Leukemia Cells by Induction of Apoptosis
... by induction of apoptosis, cell death detection ELISA was used to quantify the nucleosome production during nuclear DNA denaturation of apoptotic ...extract-induced apoptosis, the percentages of ...
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INDUCING APOPTOSIS IN CANCER THERAPY
... the induction of apoptosis in tumour ...in apoptosis is the pro- teolytic activation of cysteine aspartyl- specifi c proteases (caspases) that cleave defi ned cellular target proteins and thereby ...
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Evolutionary model tree induction
... Model trees are a particular case of decision trees employed to solve regression problems, where the variable to be predicted is continuous. They have the advantage of presenting an interpretable output, helping the ...
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Role of Calpain in Apoptosis
... in apoptosis, substrate hydrolysis Calpain activation in apoptosis was first demon- strated in thymocytes, as measured by calpain au- tolysis ...neuronal apoptosis during spinal cord injury (14). ...
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Osteoporosis Induction in Animal Model
... Radiographic observation showed a complete osteoporotic feature in Group 1. Cortical thinning as well as complete radiolucent view confirmed the osteoporosis by radiologic findings. Histopathologic findings proof the ...
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MATERIALS AND METHODS Callus induction
... On the other hand, this somaclonal variation can be a useful source of new variation for genetic breeding, mainly for the selection of cell lines with higher yie[r] ...
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Distinct Macrophage Fates after in vitro Infection with Different Species of Leishmania: Induction of Apoptosis by Leishmania (Leishmania) amazonensis, but Not by Leishmania (Viannia) guyanensis.
... through apoptosis, exposing PS on their surface being phagocytized by neighboring healthy macrophages, propagating the ...imminent apoptosis. However, there are no reports on classic apoptosis of ...
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14-3-3 proteins in apoptosis
... TNF binding to TNF-R1 also activates the recruitment of other TNF receptor-asso- ciated factors to TRADD, which via signal transduction ultimately activates the anti- apoptotic transcription factor nuclear factor kB ...
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