Beta-globin
Cis-cotranscription of two beta globin genes during chicken primitive hematopoiesis.
... Schematic diagram of chicken beta globin locus. B,C) rho (B) and epsilon (C) cytoplasmic probes stain in all blood cells at stage HH10. D,E) Intron probe against rho (D) or epsilon (E) reveals three types ...
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Frequency and origin of haplotypes associated with the beta-globin gene cluster in individuals with trait and sickle cell anemia in the Atlantic and Pacific coastal regions of Colombia
... Sickle cell anemia is a genetic disease with high prevalence in people of African descent. There are five typical haplotypes associated with this disease and the haplotypes associated with the beta-globin ...
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5'HS5 of the human beta-globin locus control region is dispensable for the formation of the beta-globin active chromatin hub.
... The human b-globin locus contains five genes that are arranged in the same order as their developmental expression pattern: 5 9-e (embryonic) Gc Ac (foetal) d b (adult)-3 9. The major activating region, termed the ...
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Dissection of the beta-globin replication-initiation region reveals specific requirements for replicator elements during gene amplification.
... In light of the results of previous studies [20-22], these data suggest that gene amplification and replication initiation at a chromosomal locus require overlapping but not identical sequences. Replication-initiation ...
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Intergenic transcription, cell-cycle and the developmentally regulated epigenetic profile of the human beta-globin locus.
... arrowheads, globin genes; pink rectangle, b-like pseudogene; white arrowheads, olfactory receptor genes; black arrowhead, UBQLN3 gene; vertical blue lines, hypersensitive sites; blue arrows, intergenic ...
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Beta-globin gene cluster haplotypes in Venezuelan sickle cell patients from the State of Aragua
... Venous blood samples were collected using EDTA as an anticoagulant, and the hematological parameters were determined by standard laboratory procedures. The buffy coat was used for the preparation of nuclear DNA accord- ...
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Unexpected pattern of beta-globin mutations in beta-thalassaemia patients from northern Portugal
... 1992; Faustino et al, 1992; Tamagnini et al, 1993). This has resulted in the assumption regarding the homogeneity of the mutations throughout the country, as well as of a low or even null incidence of the disease in the ...
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Control of human beta-globin mRNA stability and its impact on beta-thalassemia phenotype
... b- globin mRNAs. In fact, we have shown that b-globin transcripts containing naturally occurring nonsense muta- tions in the 5’ region of exon 1 accumulate to levels simi- lar to those of normal ...
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Caracterização molecular e laboratorial da talassemia beta e da interação hemoglobina s/talassemia beta
... beta globin chain synthesis and results from a number of mechanisms that lead to genetic ...of beta thalassemia is characterized by the existence of heterozygous individuals, compound heterozygotes, ...
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Genetic variations in the β-globin cluster: influence on levels of fetal hemoglobin
... (Beta Globin Locus Transcript 3), a gene lying downstream of the duplicated γ-globin genes and upstream of the adult δ-globin and β-globin gene (Figure 4) that codes for an ...
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Beta contábil X Beta CAPM: um estudo com as empresas dos setores regulados e não regulados listados na BM&FBovespa
... Faz-se necessário explicitar que o ROI ajustado foi utilizado como parâmetro do retorno das empresas, conforme estudos anteriores que afirmam ser a melhor forma de se calcular o Beta Contábil (CARDOSO; MARTINS, ...
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Caracterização de beta-lactamases em Serratia fonticola
... dos beta-lactâmicos, nomeadamente às penicilinas e aos ...das beta-lactamases de classe A, incluindo o motivo SXXK no local activo, foram identificados na sequência aminoacídica da enzima ...
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Genetic relationships among native americans based on β-globin gene cluster haplotype frequencies
... The molecular polymorphism of the β-globin gene cluster was the first nuclear DNA segment widely studied for the analysis of evolutionary relationships among human populations (Wainscoat et al., 1986). The ...
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Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1
... Methods: In this study, 28-week-old Otsuka Long-Evans Tokushima Fatty (OLETF) rats were fed a normal chow diet or a high- fat diet (HFD) and were provided with tap water or dilute bals[r] ...
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Screening for mutations in human alpha-globin genes by nonradioactive single-strand conformation polymorphism
... 9. Hall GW, Thein SL, Newland AC, Chisholm M, Traeger-Synodinos J, Kanavakis E, Katamis C & Higgs DR (1993). A base substitution (T →C) in codon 29 of the alpha 2-globin gene causes alpha thalassaemia. British ...
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Mecanismos de resistência e detecção das beta-lactamases
... As beta-lactamases são divididas em quatro classes: A, B, C e D, baseadas em suas estruturas e substratos específicos. Além disso, são subdivididas em diversos grupos, como as TEM e SHV ESBLs, comuns em diversas ...
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Uma nova abordagem da distribuição beta logística
... Para omparar distribuições não enaixados, tais omo, beta normal (BN) e beta. logístia generalizada (BGL), ada uma destas distribuições versus a distribuição beta[r] ...
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Modelos de regressão beta com erro nas variáveis
... log_pVero(const vP, const adFunc, const avScore, const amHess) {. decl vero=zeros(1,rows(vY)); decl alpha=vP[0:columns(mZ)];[r] ...
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Resistência bacteriana: a importância das beta-lactamases
... As cefalosporinas de amplo espectro com uma cadeia lateral oximino, tais como a cefotaxima, a ceftazidima e a ceftriaxona e o monobactâmico aztreonama, foram lançadas nos anos 60 com a esperança de que seriam eficazes ...
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