Cell Function
Residual ß-cell function and microvascular complications in type 1 diabetic patients
... low level of basal C-peptide. However, in 7 patients (14%) a high level of basal C-pep- tide was observed. This suggests that some type 1 diabetic patients may retain some insulin secretory capacity (3). Total or par- ...
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Oct4 targets regulatory nodes to modulate stem cell function.
... Importantly, several members of the TrxG and PcG of transcription factors such as Ash1l, Suz12, Ash2l, Phc1, and Rnf134, Bmi1, and Phc3 were correlated to Oct4, with the five latter genes validated as Oct4 targets. ...
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Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes.
... Exenatide, a synthetic analogue of exendin-4, a natural ligand of the glucagon-like peptide 1 receptor, has been extensively used for type 2 diabetes treatment. Exenatide has been shown to reduce hyperglycemia, promote ...
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Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
... and function, expression of co-stimulatory molecules, suppress dendropoiesis, and polarize DC development in vitro as well as in vivo in chemotherapy-treated patients ...
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Novel interaction between proliferating cell nuclear antigen and HLA I on the surface of tumor cells inhibits NK cell function through NKp44.
... single cell layer in tissue ...their cell surface (Figure ...replicating cell lines, which may account for the steady expression of PCNA on the surface of DB ...NK92-MI Cell Cytotoxic ...
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Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral disc
... their function and role in the developing IVD and in protecting the IVD from degeneration and; (iii) the human adult NP contains cells that express notochordal cell markers, suggesting a persistence of ...
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Modulation of innate antigen-presenting cell function by pre-patent schistosome infection.
... APC function, we questioned whether the observed impairment was cell contact- dependent or -independent and whether infection causes innate APCs to produce a diffusible suppressive or inhibitory ...T ...
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Obesogens and Male Fertility: a Threat to Sertoli Cell Function?
... germ cell development is observed in SCs that fail to proliferate or in which metabolism is perturbed, suggesting that their normal function is required for a successful ...
85
Arq. Bras. Cardiol. vol.95 número2 en a25v95n2
... β-cell function ( β+ or β-), defines the presence of diabetes mellitus type 1A, 1B, 2A and ...pancreatic function, but may evolve to insulin dependence (A+ β+), hence with periodic pancreatic ...
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Quantitative evaluation of the reticuloendothelial system function with dynamic MRI.
... to investigate the SPIO nanoparticle active binding to Kupffer cells, which may offer insight into kupffer cell function and density. Recently, the encapsulation of the bisphoaphonate clodronate into ...
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Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content.
... mast cell-specific proteases, the latter requiring serglycin proteoglycan to be stored ...mast cell function by regulating the mast cell-specific proteases and serglycin proteo- glycan, we ...
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Obesity impairs γδ T cell homeostasis and antiviral function in humans.
... requires cell- cell contact, but does not require cellular processing ...T cell function suggests that Vγ9Vδ2 TCR signaling remains func- tional in ...
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RESISTÊNCIA À INSULINA NA NEUROFIBROMATOSE TIPO 1
... Os indicadores Homeostasis Model Assessment Insulin Resistance (HOMA-IR), Homeostasis Model Assessment Beta Cell Function (HOMA- Beta); Homeostasis Model Assessment Adiponectin [r] ...
140
Polysaccharides isolated from Acai fruit induce innate immune responses.
... additional cell type, the cd T cell, which responds to at least three distinct herbal components ...dendritic cell function ...epithelial cell monolayers ...this cell type, its ...
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Insights into the cellular function of YhdE, a nucleotide pyrophosphatase from Escherichia coli.
... of cell shape, chromosom- al segregation and establishment of cell polarity ...in cell wall synthesis in the cylindrical part of the cell, leading to cell elongation ...
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The IL23R R381Q gene variant protects against immune-mediated diseases by impairing IL-23-induced Th17 effector response in humans.
... single cell level [37] we performed phospho-flow cytometry analysis, providing us with both a higher sensitivity and specificity than conventional western blot analysis (data not ...
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Rev. Bras. Hematol. Hemoter. vol.35 número4
... sickle cell anemia who attended meetings held by the Associação Baiana de Portadores de Doenças Falciformes, an association for sickle cell anemia patients in Bahia, were ...
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Protective effects of mesenchymal stem cells with CXCR4 up-regulation in a rat renal transplantation model.
... In conclusion, we have demonstrated that MSC therapy ameliorates the negative effects of IRI in a very strong, clinically relevant model of rat kidney transplantation at early time points. CXCR4 plays a critical role not ...
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The Arabidopsis thaliana F-box protein FBL17 is essential for progression through the second mitosis during pollen development.
... pollen cell fate, we introduced in the fbl17 +/ 2 background the ...generative cell and subsequently in sperm cells ...generative-like cell nuclei of fbl17- 1 mutant (n = 95), indicating that this ...
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Characterization of natural killer cell phenotype and function during recurrent human HSV-2 infection.
... Genital herpes simplex virus type 2 (HSV-2) infection is the most common sexually transmitted ulcerative disease worldwide [1]. The clinical presentation of HSV-2 infection ranges from asymptomatic disease to recurrent ...
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