Clinical studies
Non-clinical studies in the process of new drug development – Part II: Good laboratory practice, metabolism, pharmacokinetics, safety and dose translation to clinical studies
... and clinical studies. Non-clinical studies are conducted using different protocols including animal studies, which mostly follow the Good Laboratory Practice (GLP) ...pre- ...
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Bias in clinical studies
... Clinical studies are designed fundamentally to obtain data to support practice, whether diagnostic, therapeutic or prognostic. No matter how well a study was designed, implemented or analyzed, it is never ...
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Non-clinical studies required for new drug development – Part I: early in silico and in vitro studies, new target discovery and validation, proof of principles and robustness of animal studies
... non-clinical studies, such as: i) sanitary quality of experimental ani- mals; ii) animal distribution in the different experimental groups; iii) sample size calculation; iv) management of experiments; v) ...
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Integration of information technologies in clinical studies in Nicaragua.
... in clinical studies has numerous advantages, such as improved QC, streamlined laboratory and fieldwork procedures, increased efficiency and reduced costs, real-time analysis of data, local capacity building, ...
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Genetic and Molecular Basis of Arrhythmias
... of clinical studies have al- ready been performed in the attempt of correlating the clinical manifestation of the disease and the risk of cardiac event with the genetic defect found in ...based ...
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Dement. neuropsychol. vol.9 número4
... in clinical studies; [2] to determine whether diferent neu- roimaging criteria impact over cognitive indings, and [3] to identify neuropsychological tests that could distin- guish VaMCI from normal controls ...
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Rev. Bioét. vol.24 número1
... During the course of human history, children and adolescents have oten been the vicims of science in clinical studies. When society was confronted with the horrors of the experiments conducted during World ...
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Rev. Assoc. Med. Bras. vol.62 número5
... 48 studies analyzed were can- celed during the approval process due to impractical dead- lines noted with the CONEP, ANVISA or both, empha- sizing the country’s ineficiency to compete in the clinical ...
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Perceptions and electric senoidal current stimulation
... with clinical studies which disclosed an association between the d i ff e rent currents and clinical tests of the diff e re n t fiber systems as well with works relating sensations, electric senoidal ...
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Arq. Bras. Cardiol. vol.72 número3
... randomized studies. In conclusion, randomized clinical studies can be considered the gold standard for the assessment of the efficacy of most therapeutical inter- ventions in ...
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Key words: Proprioceptive Neuromuscular Facilitation (PNF), rehabilitation, traumatic peripheral lesion,
... the clinical treatment and from the physical rehabilitation should be directed to make them as independent as possible, obviously, within the limitations imposed by the injury (Siqueira, ...of clinical ...
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J. Pediatr. (Rio J.) vol.83 número5 suppl. en v83n5Sa04
... initial studies report significant improvement in arterial blood pressure and the possibility of reducing other vasoactive drugs, but there are reports of ischemia of the intestines or extremities, oliguria, ...
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Acute clinical manifestations in toxic smoke inhalation victims: systematic review of observational studies
... Earlier studies have explained the role of early recognition and prompt management in the presence of smoke inhalation injury [37, 38]. Another study included [20] in this systematic review also demonstrated that ...
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Clinical and Morphological Studies on Spontaneous Cases of Pseudomonas aeruginosa Infections in Birds
... bacteriological studies were performed on broiler chickens, growing broiler parents, and growing egg layers, in three different poultry farms, after an outbreak of Pseudomonas aeruginosa ...
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Cad. Saúde Pública vol.18 número5
... in studies sponsored by drug companies and other nongovernmental orga- nizations, the commission recommends that ...from clinical trials that do not meet the substantive ethical protec- tions outlined in ...
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Cryptosporidium infection in ostriches (Struthio camelus) in Brazil: Clinical, Morphological and Molecular Studies
... Avian cryptosporidiosis has been reported in more than 30 species of birds. To date, the species infecting birds are C. baileyi, C. galli and C. meleagridis. In this study, the morphological, clinical and ...
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Rev. dor vol.18 número1
... However, included studies have shown that heating tools are beneficial for pain management of OA patients. Al- though they do not stand out with regard to conven- tional kinesiotherapy, they may complement ...
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Comparison between unimodal and multimodal Physical Therapy interventions in frailty: a systematic review
... multifactorial characteristics of falls, multimodal interventions that treat many risk factors as possible, would be more effective than unimodal interventions. However, it is necessary a study that aims to compare ...
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CoDAS vol.26 número3
... development. Studies report that these individuals have linguis- tic deicits that are reflected on difficulties with all aspects related to language (phonology, pragmatics, semantics, syntax, and ...
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Rev. Assoc. Med. Bras. vol.63 número5
... syn-phospho clinical study refers to whether its potential beneits for patients and the knowledge gained by society do in fact outweigh the risks for ...any clinical trial of a new drug or therapeutic ...
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