Cyclin D1
Cyclin D1 expression in prostate carcinoma
... cyclin D1 expression in order to confirm these ...of cyclin D1 immunostain- ing observed in this study is in agreement with the results of Han et ...that cyclin D1 expression ...
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MicroRNA-195 inhibits the proliferation of human glioma cells by directly targeting cyclin D1 and cyclin E1.
... downregulated cyclin D1 and cyclin E1, and luciferase reporter assays demon- strated that miR-195 targeted cyclin D1 and cyclin E1 via the miR-195 binding sites in their 3 ...of ...
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Mesenchymal stem cells promote liver regeneration and prolong survival in small-for-size liver grafts: involvement of C-Jun N-terminal kinase, cyclin D1, and NF-κB.
... To date, however, a few investigations have been done on the potential use of MSCs to improve the outcome of small for size liver transplantation (SFSLT). The therapeutic mechanisms of MSCs are also not clearly ...
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A DNA enzyme targeting Egr-1 inhibits rat vascular smooth muscle cell proliferation by down-regulation of cyclin D1 and TGF-β1
... However, cyclin D1 and TGF-β1 mRNA syntheses were significantly inhibited by ED5 ...that cyclin D1 is regulated by Egr-1. The cyclin D1 expression study reported here not only ...
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MiR-499 regulates cell proliferation and apoptosis during late-stage cardiac differentiation via Sox6 and cyclin D1.
... of Cyclin D1 is required by cardiomyocytes for cell cycle exit and maturation during the late stage of ...inhibits cyclin D1 expression by interacting with β-catenin and HDAC1 in insulinoma ...
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p14ARF post-transcriptional regulation of nuclear cyclin D1 in MCF-7 breast cancer cells: discrimination between a good and bad prognosis?
... More recently, neoplastic cells have been shown to spontane- ously arise from senescence-associated oxidative DNA damage [58]. Interestingly, it has been shown that after release from p21- induced growth arrest abnormal ...
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A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation.
... a cyclin D1 antibody and immunoblotted with a HA antibody (upper panel) or a cyclin D1 antibody (lower ...to cyclin D1, cyclin E, Flag (FBXW7), GFP and ...of cyclin ...
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Patricy de Andrade Salles1 , Juliana Chagas Fortes2
... D-type cyclin although this cyclin D is expressed ubiquitously it cannot substitute for the two missing D-type cyclins in all regions of the de- veloping embryo (Ciemerych et ...only cyclin D3 lack ...
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miR-127 regulates cell proliferation and senescence by targeting BCL6.
... conversely, that BCL6 expression was up-regulated in breast tumors compared with their corresponding tumor-adjacent tissues (Figure 6). In primary breast tumors,miR-127 expression is lower, and BCL6 expression is higher ...
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Polimorfismo no gene da Ciclina D1 em neoplasias associadas a vírus
... the cyclin D1 proteins encoded by the two transcripts (a and b) is in the C-terminal PEST-rich region (destruction box) encoded by exon 5 which is responsible for rapid intracellular degradation and ...
133
Avaliação da expressão de β-catenina e ciclina D1 como biomarcadores preditivos...
... β-catenin, cyclin D1 and Ki-67 expression in 15 specimens of normal oral epithelium, 45 dysplastic actinic cheilitis and 30 squamous cell carcinoma of the ...of cyclin D1 and Ki-67 in the ...
133
Expression of SIRT1 and DBC1 is associated with poor prognosis of soft tissue sarcomas.
... USA), cyclin D1 (1:100, Cell Signaling Technology, clone 92G2, MA, USA), and Ki67 (1:100, DAKO, clone MIB1, Glostrup, Den- ...and cyclin D1 were evaluated to estimate the nuclear positivity of ...
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Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer Cells.
... Cyclin D1 expression was regulated by diverse signal transduction events including Wnt pathway, Akt pathway [35, ...of Cyclin D1 by binding to its promote [37, ...
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Braz. Dent. J. vol.15 número2
... of cyclin D1 with the expression of p21 in 28 cases of oral squamous cell carcinoma (OSCC), as well as to compare the expression of both with a histological graduation of this ...of cyclin D1 ...
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Water extract of Ashwagandha leaves has anticancer activity: identification of an active component and its mechanism of action.
... that cyclin D1 forms a complex with CDK4 or CDK6 and is absolutely required for G1/S ...transition. Cyclin D1-CDK4/CDK6 complex forms an active kinase for the retinoblastoma protein (RB) ...
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UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/β-catenin pathway.
... and cyclin D1 regulating cancer proliferation, MMP-7 regulating cancer invasion ...and cyclin D1 mRNA and protein levels in 786-O ...and cyclin D1 mRNA and protein levels in ACHN ...
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Arq. Gastroenterol. vol.46 número4
... and cyclin D1 proteins was scored semiquantitatively on a graded scale of 0 through 4 for both intensity and distribution by three investigators in a blinded ...
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A phase II trial of sorafenib in metastatic melanoma with tissue correlates.
... for cyclin D1 and Ki67, and total number of tumor cells were counted manually at 406 magnification using photographs taken from the individual tumor sections selected by the ...
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In vitro effects of a small-molecule antagonist of the Tcf/ß-catenin complex on endometrial and endometriotic cells of patients with endometriosis.
... for Cyclin D1 (Merck Millipore), ß- catenin (DAKO), and Actin (Sigma-Aldrich) were ...(Cyclin D1:1:30; ß-catenin: 1:800; Actin: 1:500) in blocking buffer were added to the blot holders and ...
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Rev. Bras. . vol.73 número1 en a15v73n1
... the Cyclin D1 as a risk factor for the presence of cervical ...methods: Cyclin D1 expression was measured and the association between such substance and metastasis was found in 45 patients ...
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