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Formalin test

Antinociceptive local effect of the combination of dexketoprofen trometamol and chlorhexidine gluconate in a formalin test: an additive effect

Antinociceptive local effect of the combination of dexketoprofen trometamol and chlorhexidine gluconate in a formalin test: an additive effect

... dilute formalin (5%) alone or mixed with the appropriated concentrations of formulations using a 30-gauge ...of formalin test, the areas under the curve (AUC) were calculated by trapezoidal method ...

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Comparison of the Analgesic Effect of Diclofenac Sodium-Eudragit® RS100 Solid Dispersion and Nanoparticles Using Formalin Test in the Rats

Comparison of the Analgesic Effect of Diclofenac Sodium-Eudragit® RS100 Solid Dispersion and Nanoparticles Using Formalin Test in the Rats

... the formalin test results, the nanoparticles and solid dispersion of diclofenac Na and Eudragit ® RS100 showed higher intense and also duration of analgesic effects than pure drug which could be attributed ...

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Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis.

Synergistic analgesia of duloxetine and celecoxib in the mouse formalin test: a combination analysis.

... EPM test was done according to our previous reports [28,29] with some modifications for mice. Briefly, the Plexiglas apparatus consisted of a plus-shaped platform elevated 50 cm from the floor. Two of the opposing ...

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Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia

Contribution of the rostral ventromedial medulla to post-anxiety induced hyperalgesia

... with formalin or not, is evident in mice tested with formalin upon removal from the EPM, and does not occur when rats are injected with formalin and tested on the hot plate, but not exposed to the ...

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Rev. bras. farmacogn.  vol.21 número6

Rev. bras. farmacogn. vol.21 número6

... Capsaicin was dissolved in ethanol, dimethyl sulfoxide and distilled water (1:1:8). In a pilot study, rodents manifested nociception-related face-rubbing behaviour following the injection of capsaicin with a high ...

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Rev. bras. farmacogn.  vol.21 número5

Rev. bras. farmacogn. vol.21 número5

... The neurogenic and inlammatory pain was evaluated using formalin test. Drugs that act primarily as central analgesics inhibit both phases while peripherally acting drugs inhibit only the phase 2 (Rosland et ...

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Rev. dor  vol.13 número1 en a11v13n1

Rev. dor vol.13 número1 en a11v13n1

... second formalin test phase with a possible interaction of serotonin with 5-HT 1A -type receptors present in large quantities in the som- atosensory and prefrontal ...

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Antiinflammatory and  activity of , an imidazole alkaloid isolated from pilocarpus microphyllus

Antiinflammatory and activity of , an imidazole alkaloid isolated from pilocarpus microphyllus

... of formalin significantly in both test phases: the neurogenic (phase 1, ...the formalin test ...this test, pretreatment with 1 inhibited paw edema induced by serotonin and bradykinin, ...

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Rev. bras. farmacogn.  vol.22 número1

Rev. bras. farmacogn. vol.22 número1

... The observation chamber was a glass box of 30 cm diameter on an acrylic transparent plate floor. Beneath the floor, a mirror was mounted at a 90 ºC angle to allow clear observation of the paws of the animals. The animals ...

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Rev. bras. farmacogn.  vol.18 número3

Rev. bras. farmacogn. vol.18 número3

... hot-plate test and the reactivity to the chemical stimulation in the formalin test fi rst phase, indicating a non-opioid ...the formalin-induced nociception in the second phase, inhibited the ...

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Rev. Bras. Cienc. Farm.  vol.44 número4

Rev. Bras. Cienc. Farm. vol.44 número4

... of formalin tests (200 ...writhing test was ...the formalin test (second phase) results were ...toxicity test, oral administration of 5 g/kg of AEEV was performed and no mortality rate ...

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J. Braz. Chem. Soc.  vol.25 número11

J. Braz. Chem. Soc. vol.25 número11

... The residual aqueous fraction of the liquid-liquid partition of the ethanol extract from seeds of Aspidosperma pyrifolium showed antinociceptive and anti-inflammatory activities in the formalin test, ...

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The antiinflammatory and  effects of proteins extracted from Acacia farnesiana seeds

The antiinflammatory and effects of proteins extracted from Acacia farnesiana seeds

... the formalin test, the pain in the mice paws involves two distinct ...plate test, these results indicate that the proteins present in the GLB fraction do not act via supra spinal and spinal ...and ...

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Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway

Antinociception synergy between the peripheral and spinal sites of the heme oxygenase-carbon monoxide pathway

... the formalin test, a small amount of diluted formalin solution is injected subcutaneously into the rat hind paw, resulting in a reproducible biphasic behavioral response (25), which can be subdivided ...

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Rev. bras. farmacogn.  vol.21 número6

Rev. bras. farmacogn. vol.21 número6

... lip: formalin, capsaicin, and ...the formalin test (first phase, 0-6 min; and second phase, 21-40 min), and for 42 and 15 min in the capsaicin and glutamate tests, ...Rota-rod test was ...

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Antinociceptive properties in mice of a lectin isolated from the marine alga Amansia multifida Lamouroux

Antinociceptive properties in mice of a lectin isolated from the marine alga Amansia multifida Lamouroux

... the formalin test, although both phases of the response were significantly inhibited, the effect of LEC was predomi- nant during phase 2, causing inhibition of licking time that ranged from 48 to 88% after ...

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Peripheral  and antiedematogenic effect of a sulfated  from Acanthophora muscoides

Peripheral and antiedematogenic effect of a sulfated from Acanthophora muscoides

... the formalin test, but it did not alter the response latency in the hot plate test, suggesting that its antinociceptive action occurs through a peripheral ...

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Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice

Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice

... the formalin test from the control value of ...formalin test. As evaluated by the hot-plate and tail immersion test, EOMV and PO, at doses up to 200 mg/kg, showed no analgesic ...

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Repositório Institucional da UFPA: Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice

Repositório Institucional da UFPA: Antinociceptive effects of the essential oil of Mentha x villosa leaf and its major constituent piperitenone oxide in mice

... the formalin test from the control value of ...formalin test. As evaluated by the hot-plate and tail immersion test, EOMV and PO, at doses up to 200 mg/kg, showed no analgesic ...

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Rev. bras. farmacogn.  vol.26 número1

Rev. bras. farmacogn. vol.26 número1

... of formalin test, but only the pheno- lic and alcoholic extracts had been able to prevent the first phase of the formalin ...hotplate test, and stomach graze induced by high dose ...

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