Genetic Risk
Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants
... a genetic risk score to traditional risk factors associated with coronary ...Thirty-three genetic variants previously associated with coronary disease were analyzed in a case-control ...
12
Performance of an adipokine pathway-based multilocus genetic risk score for prostate cancer risk prediction.
... multilocus genetic risk score by weighting each risk SNP empirically based on its association with ...of genetic variants to age and PSA improved the predictive accuracy for overall and ...
9
A genetic risk score combining ten psoriasis risk loci improves disease prediction.
... that genetic predisposition has a critical role in the development of psoriasis ...as risk factors for the development of psoriasis ...greatest genetic effect in Caucasians, particularly for early ...
7
Smaller genetic risk in catabolic process explains lower energy expenditure, more athletic capability and higher prevalence of obesity in Africans.
... more genetic risk in the catabolic process may cause the decrease of efficiency in generating energy, so it has been observed that Europeans need more EE than Africans in the same routine ...
11
Genetic Risk Analysis of Coronary Artery Disease in a Population-based Study in Portugal, Using a Genetic Risk Score of 31 Variants
... Thirty-three genetic variants previously associated with coronary disease were analyzed in a case-control population with 2,888 ...multiplicative genetic risk score was calculated and then divided ...
12
Modelling the genetic risk in age-related macular degeneration.
... that genetic predisposition influences disease onset, which is also reflected in the higher relative AMD risk for younger subjects with an OR of ...mean genetic risk score in our control group ...
10
Genetic Risk Analysis of Coronary Artery Disease in a Population- based Study in Portugal, Using a Genetic Risk Score of 31 Variants
... Thirty-three genetic variants previously associated with coronary disease were analyzed in a case-control population with 2,888 ...multiplicative genetic risk score was calculated and then divided ...
12
Additional value of a combined genetic risk score to standard cardiovascular stratification
... of genetic risk scores (GRS) as independent risk predictors remains ...Framingham risk score (FRS) in coronary artery disease (CAD) risk predic- ...32 genetic variants associated ...
9
No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.
... Host genetic factors may be a contributor to influenza ...the risk of influenza-associated death ...relative risk for relatives dying of influenza was larger than for ...the risk due to ...
10
Identification of genetic risk factors for Behçet’s disease
... a genetic model and instead relies on the principle that affected relatives share haplotypes that are identical by descent (IBD) in the region of a disease causing gene more often that would be expected by chance ...
215
Factors Motivating Individuals to Consider Genetic Testing for Type 2 Diabetes Risk Prediction.
... in genetic testing for T2D ...pursue genetic testing included: anxiety about genetic testing; older age; lower levels of education; and high perceived discrimination from employers and ...high ...
12
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta
... in risk stratification for CAD [27,28,29], the CAD GRS used in the present study does not seem to have any association with CIMT or CAE measured in a cross-sectional study setting or with the development of these ...
10
Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis.
... the risk from South to North (Pearson’s r = ...highest risk scores when compared with the rest of the European continent (Tables S8 and ...in genetic risk is also reflected in differences in ...
16
Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.
... 40 genetic susceptibility loci have been reported for type 2 diabetes ...of genetic variants has been investigated by calculating a genetic risk ...two genetic risk scores (GRS) ...
7
Genetic Variants Underlying Risk of Intracranial Aneurysms: Insights from a GWAS in Portugal
... novel genetic risk variants and have brought novel insights into the biological and genetic underpinnings of many complex ...five risk loci explain only up to 5% of the familial risk of ...
12
Rev. Bras. Psiquiatr. vol.33 suppl.2
... were genetic risk for psychosis with recent functional deterioration, higher levels of unusual thought content, higher levels of suspicion/paranoia, more severe social impairment, and a history of drug ...
7
Clinics vol.68 número12
... a genetic risk score based on 101 SNPs in 19,313 healthy Caucasian women who were followed up over a median of ...cardiovascular risk factors, the genetic risk score was not associated ...
7
Genetic counseling and presymptomatic testing programs for Machado-Joseph disease: lessons from Brazil and Portugal.
... Diagnostic genetic testing is available to detect the disease-causing mutation by direct sizing of the CAG repeat tract in the ataxin 3 ...at risk of developing the disease. Genetic counseling ...
8
Genetic Determinants of Metabolism and Benign Prostate Enlargement: Associations with Prostate Volume.
... because genetic factors leading to advanced PC are likely to be distinct from those involved in prostate enlargement, and men with high-grade PC had significantly smaller prostate volume and higher PSA levels than ...
14
Re: Lack of association between Matrix Metalloproteinase-1 (MMP-1) promoter polymorphism and risk of renal cell carcinoma
... for genetic polymorphism will lead to an early diagnosis of can- cer in these ...high- risk alleles will take advantage of a strict clinical sur- veillance for example with periodic ultrasound ...increased ...
2