Glutathione S-transferases
Cytochrome P450 (CYP) and glutathione S-transferases (GST) polymorphisms (CYP1A1, CYP1B1, GSTM1, GSTP1 and GSTT1) and urinary levels of 1-hydroxypyrene in Turkish coke oven workers
... Many carcinogens, including PAHs, are detoxified by Phase II enzymes such as glutathione S-transferases (GSTs) (Ketterer and Mulder, 1990). The three GST classes (GSTM, GSTT and GSTP) constitute an ...
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Molecular Docking of Anopheles gambiae and Aedes aegypti Glutathione S-Transferases Epsilon 2 (GSTE2) Against Usnic Acid: an Evidence of Glutathione Conjugation
... The Glutathione S-tranferases (GSTs) is a highly promiscuous enzyme super family that plays an essential role in cytoplasm detoxification of a large range of xenobiotic compounds in many organisms ...
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Ilex paraguariensis extracts extend the lifespan of Drosophila melanogaster fed a high-fat diet
... Studies have suggested that total energy intake and diet composition affect lifespan and ageing. A high-fat diet induces oxidative stress and affects the development of diseases. In contrast, antioxidants are capable of ...
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Rev. bras. epidemiol. vol.15 número2
... Genetic polymorphisms in genes related to the metabolism of xenobiotics, such as genes of the glutathione S-transferases (GSTM1, GSTT1, and GSTP1) superfamily have been associated with an increased ...
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A glutathione s-transferase confers herbicide tolerance in rice
... Plant glutathione S-transferases (GSTs) have been a focus of attention due to their role in herbicide ...a glutathione S-transferase, lambda class gene from rice (Oryza sativa ...
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Distribution of glutathione S-transferase GSTM1 and GSTT1 null phenotypes in Brazilian Amerindians
... Glutathione S-transferases (GSTs) are a superfamily of enzymes that are involved in the detoxification of reac- tive metabolites of carcinogens and may therefore be im- portant in modulating ...
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Glutathione S-Transferase Regulation in Calanus finmarchicus Feeding on the Toxic Dinoflagellate Alexandrium fundyense.
... The glutathione S-transferases are a family of proteins involved in a variety of cellular func- tions, including detoxification ...with glutathione in its reduced form (GSH), which in turn ...
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Superoxide dismutase, catalase, glutathione peroxidase and gluthatione S-transferases M1 and T1 gene polymorphisms in three Brazilian population groups
... The glutathione S-transferases M1 (GSTM1) and T1 (GSTT1) genes code for the cytosolic enzymes GST-m (mu) and GST-q (theta), ...reduced glutathione (GSH) and a variety of eletrophilic compounds ...
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A glutathione s-transferase confers herbicide tolerance in rice
... Plant glutathione S-transferases (GSTs) have been a focus of attention due to their role in herbicide ...a glutathione S-transferase, lambda class gene from rice (Oryza sativa ...
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Crystallization and preliminary X-ray diffraction analysis of a glutathione S-transferase from Xylella fastidiosa
... the glutathione S-transferase enzyme (GST) with 205 amino acids ...The glutathione S-transferases form a group of multifunctional isoenzymes that catalyze the ...
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Biomarkers of kidney integrity in children and adolescents with dental amalgam mercury exposure: findings from the casa pia children’s amalgam trial.
... environmental chemicals. The release of cytoplasmic proteins and other constituents into the urine following injury to tubular cells has long been clinically exploited to assess the site and severity of renal tubular ...
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Ethnicity and glutathione S-transferase (GSTM1GSTT1) polymorphisms in a Brazilian population
... The glutathione S-transferases (GST) are an important enzymatic system of the cellu- lar mechanism of detoxification that pro- tects cells against reactive oxygen metabo- lites due to the conjugation ...
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Combined GSTM1 and GSTT1 null genotypes are strong risk factors for
... since glutathione S-transferases (GSTs) provide protection against OS, we have tested the hypothesis that deletion polymorphisms in two GSTs (GSTM1 and GSTT1) may affect the risk of developing ...
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Nullity of GSTT1/GSTM1 related to pesticides is associatedwith Parkinson's disease
... (CYP2E1), glutathione S-transferases (GST), superox- ide dismutase (MnSOD), monoamine oxidase-B (MAO-B), do- pamine receptor D2 (DRD2) and dopamine transporter (DAT) which are known to interact with ...
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Glutathione S-transferase M1 (GSTM1) polymorphism in two Brazilian populations
... The glutathione S-transferases: their role in the trans- port of organic anions from blood to ...the glutathione S-trans- ferase GSTM1 locus: a study of the frequencies of the GSTM1 A, ...
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Genomic Analysis of Detoxification Supergene Families in the Mosquito Anopheles sinensis.
... The evolution of insecticide resistance occurs through complicated mechanisms, typically requiring the interaction of multiple genes [19]. Knowledge of the molecular mechanism of insecticide resistance is a basic ...
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Role of glutathione in tolerance to arsenite in Salvinia molesta, an aquatic fern
... An essential mechanism for As tolerance in plants involves the complexes formed between the metalloid and rich SH-group compounds, especially the reduced glutathione molecule (GSH). The As-GSH complexes can be ...
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Dement. neuropsychol. vol.2 número1
... The detoxification of H 2 O 2 is done by glutathione peroxidase (GPx) in the presence of reduced glutathione (GSH), leading to the formation of oxidized glutathione (GSSG).. Glutathion[r] ...
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EVALUATION OF SERUM CHOLESTEROL, AMINO TRANSFERASES
... Thus, this study was performed to determine the efficacy of red yeast rice (Monascus purpureus-fermented rice) in lowering cholesterol levels in the blood and to evaluat[r] ...
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Effects of cisplatin on lipid peroxidation and the glutathione redox status in the liver of male rats: The protective role of selenium
... for glutathione (reduced glutathione-GSH and oxidized glutathione-GSSG) assays were homogenized on ice with 20 volumes of precipitating solution ...
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