Human liver
Regulation of coagulation factor XI expression by microRNAs in the human liver.
... High levels of factor XI (FXI) increase the risk of thromboembolic disease. However, the genetic and environmental factors regulating FXI expression are still largely unknown. The aim of our study was to evaluate the ...
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Selective protection of human liver tissue in TNF-targeting of cancers of the liver by transient depletion of adenosine triphosphate.
... [21]. Human liver tissue slices with a diameter of ...6 liver cells in average, were prepared from freshly resected liver tumors and corresponding non-malignant liver tissue, incubated ...
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Mechanism of action of novel piperazine containing a toxicant against human liver cancer cells
... against human liver cancer cells. SNU-475 and 423 human liver cancer cell lines were used to determine the IC50 of PCC using the standard MTT ...on liver cancer cells with an IC50 value ...
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AGE WISE HISTOMORPHOLOGICAL CHANGES IN HUMAN LIVER
... of liver in different age groups, the liver is organised into lobules, which take the shape of irregular polygonal ...the human liver is not immediately evident under the ...
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Extracellular Matrix Molecular Remodeling in Human Liver Fibrosis Evolution.
... decellularized human liver tissue (Fig 2A, left and middle panel respectively), as well as the immunostaining for fibronectin showed that the isolated liver ECM scaffold retained the typical network ...
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Gene expression profiling and secretome analysis differentiate adult-derived human liver stem/progenitor cells and human hepatic stellate cells.
... Adult-derived human liver stem/progenitor cells (ADHLSC) are obtained after primary culture of the liver parenchymal ...the liver non-parenchymal fraction, present a comparable morphology as ...
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Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells
... literature for the major components of the ethyl acetate extract of M. convoluta, i.e., phytol, caryophyllene and caryophyllene oxide, are consistent with the traditional uses of this plant to treat skin tumefaction, to ...
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Clinical Outcomes and Genetic Expression Profile in Human Liver Graft Dysfunction During Ischemia/Reperfusion Injury
... We collected patient age, gender, main pathology, blood group, preoperative Model for End-Stage Liver Disease (MELD) score, Child ePugh score, and Survival Outcomes Following Liver Trans- plantation (SOFT) ...
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NADH oxidase activity of rat and human liver xanthine oxidoreductase: potential role in superoxide production
... rat liver XOR, the purified enzymes were reduced with an excess of dithionite for 30 min, and the X-band EPR spectra were acquired at different temperatures (20–100 ...avian liver XD ...
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A highly efficient, stable, and rapid approach for ex vivo human liver gene therapy via a FLAP lentiviral vector
... 1). Human hepatocytes were transduced while still in suspension during a 2-hour ...and human hepa- tocytes are efficiently transduced by FLAP lentiviral vec- tors without the need for plating or ...In ...
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A CORROSION CAST STUDY OF RAMIFICATION PATTERN OF PORTAL VEIN IN RIGHT LOBE OF HUMAN LIVER
... ed liver w as placed in 10 % form al saline for 24 hours at room t em perat ure (20°C) f or polym erizat ion of inf used but yl but yrat e solut ...of liver t issue achieved by w hole- organ im m ersion in ...
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Genome-wide discovery of drug-dependent human liver regulatory elements.
... Our RNA-seq analyses that combined eight different individuals identified 157 differentially expressed genes, using a p-value cutoff that adjusted for multiple testing less than or equal to 0.05 (Table S1). Many of these ...
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Interleukin-8 is activated in patients with chronic liver diseases and associated with hepatic macrophage accumulation in human liver fibrosis.
... Besides the clear association of IL-8 with disease progression, we noticed distinct differences in IL-8 serum and intrahepatic expression dependent on the underlying disease etiology. Patients with alcoholic, but ...
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Liver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failure.
... a human liver cell line that displays a high and broad level of hepatic ...The human bipotent liver progenitor cell line HepaRG is a promising candidate in this respect, for its potential to ...
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Completion of hepatitis C virus replication cycle in heterokaryons excludes dominant restrictions in human non-liver and mouse liver cell lines.
... Finally, to explore the importance of the time point of IFN- treatment for virus production in the heterokaryon fusion assay between Hep56.1D packaging cells and Huh-7.5 replicon cells, we applied mouse IFN-a for 4 h at ...
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Meta-analysis of inter-species liver co-expression networks elucidates traits associated with common human diseases.
... a liver expression study were used ...the human liver, and are also in the three conserved co-expression modules we identified as associated with the blood lipid ...loci, human cis eSNP genes ...
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Liver transplantation for colorectal liver metastasis: Survival without recurrence can be achieved
... primary. Liver grafts were from 6 non-marginal donors after brain-death, 5 domino donors with familial amyloid polyneuropathy, and one living-related ...previous liver resection in 6 ...following ...
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Silencing of augmenter of liver regeneration inhibited cell proliferation and triggered apoptosis in U266 human multiple myeloma cells
... Figure 2. Augmenter of liver regeneration (ALR) regulated the proliferation of U266 multiple myeloma (MM) cells. A, U266 MM cells were exposed to 20 or 40 mg/mL recombinant ALR protein for 24–72 h and cell ...
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The protective role of transcription factor NRF2 against liver injury in human and mouse models of Hereditary Hemochromatosis
... The liver, in particular, accumulates large amounts of ...In liver fibrosis, Kupffer cells (resident liver macrophages) give stimuli for the progression of the fibrogenetic ...of liver ...
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MR Assessment of liver and pancreas steatosis in chronic liver diseases
... During pancreatic transplant procedures, a direct inspection of the organ can classify pancreatic steatosis as mild or massive, [3] while in the histological examinations, the increased number of pancreatic fat is ...
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