immune activation
Lgt processing is an essential step in Streptococcus suis lipoprotein mediated innate immune activation.
... Generation and characterization of a S. suisDlgt mutant To distinguish between lipoprotein and non-lipoprotein medi- ated innate immune activation of porcine PBMCs, we constructed a mutant S. suis serotype ...
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Gender-dependent effects of maternal immune activation on the behavior of mouse offspring.
... that immune stimulation during fetal development in mice causes differential effects in males ...utero immune activation on repetitive and other autistic-like ...
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Effects of early or late prenatal immune activation in mice on behavioral and abnormalities relevant to schizophrenia in the adulthood
... tal immune activation induced by LPS or poly I:C may alter the mesolimbic dopaminergic system by increasing the immunoreac- tivity of tyrosine hydroxylase in the nucleus accumbens (Meyer and Feldon, ...
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Coincident helminth infection modulates systemic inflammation and immune activation in active pulmonary tuberculosis.
... systemic immune activation markers more accurately reflect inflammatory pathology in chronic ...monocyte/macrophage activation and their levels in the blood usually reflect chronic immune ...
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Structural and functional analyses of DNA-sensing and immune activation by human cGAS.
... In the presence of dsDNA, cGAS produces cGAMP from GTP and ATP, which activates STING as a second messenger [17,1κ]. Activated STING induces TBK1-dependent phosphorylation of IRFγ, resulting in the production of IFN- ...
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Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART.
... To further investigate the effect of immunization with Tat, key biomarkers of AIDS pathogenesis and progression used to evaluate HAART efficacy were determined as second-line exploratory testing. These included ...
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IDO chronic immune activation and tryptophan metabolic pathway : a potential link between depression and obesity
... depression. Activation of cell- mediated immunity (CMI) is a key factor in the pathophysiology of ...of immune activation, IDO stimulation and increased TRYCAT production in the pa- thophysiology of ...
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Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by Plasmin.
... A surprising observation was that plasmin also attenuated the ability of dendritic cells to mount an adaptive immune response. This was concluded from in vitro mixed lymphocyte reactions (Fig 4) and in vivo ...
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Preliminary analysis of immune activation in early onset type 2 diabetes
... TLR4 activation can upset the normal balance of the immune system promoting insulin ...in immune genetics be- tween Manitoban Indigenous peoples and ...
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Hemophagocytic lymphohistiocytosis, a rare condition in renal transplant - a case report Linfohistiocitose hemofagocítica, condição rara no transplante renal - relato de caso
... is an uncommon and life-threating con- dition characterized by major immune activation and massive cytokine produc- tion by mononuclear inflammatory cells, due to defects in cytotoxic lymphocyte function. ...
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iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats.
... potential immune activation by penetrating bacteria, mucus thickness increases in colitic rats 3–8 days after DSS administra- tion in parallel with increased goblet cell number and mucus ...
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Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
... chronic immune activation/ inflammation [9], along with viral persistence, CD4 + T cell lymphopenia, Th17 loss, a change in the regulatory T cell balance, disruption of the lymph node architecture, viral ...
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A Decreased Frequency of Regulatory T Cells in Patients with Common Variable Immunodeficiency
... Materials and Methods: Sixteen patients (6 males and 10 females) with CVID who had been treated with regular intravenous immunoglobulin and 14 controls were enrolled. Quantitative analyses of peripheral blood mononuclear ...
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Interferon-alpha administration enhances CD8+ T cell activation in HIV infection.
... in immune activation as viremia ...of immune activation and inflammation in chronic HIV infection ...to immune activation in HIV ...
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Decreased naive and increased memory CD4(+) T cells are associated with subclinical atherosclerosis: the multi-ethnic study of atherosclerosis.
... persistent immune activation and inflammation resultant from chronic pathogenic ...innate immune responses by T helper and Treg cells; and loss of thymic output leading to immunosenescence ...
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Ginseng Berry Extract Promotes Maturation of Mouse Dendritic Cells.
... A recent effort in the development of new medication and immunomodulatory agents is to search for candidates among natural products, since they have relatively low toxicities in clini- cal applications [1]. Ginseng root ...
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The relative importance of innate immune priming in Wolbachia-mediated dengue interference.
... Host immune priming by Wolbachia offers an appealing mechanistic explanation for pathogen blocking as it is conceivable that this single effect could lead to protection against a diversity of ...the immune ...
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KIR-HLA genotypes in HIV-infected patients lacking immunological recovery despite effective antiretroviral therapy.
... sustained immune recovery, although the corresponding mecha- nisms could be only ...and immune activation. Higher levels of immune activation have been described in immunological non ...
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R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes.
... of immune activation and regulation of PB versus LN- derived CD4 and CD8 T cells, regardless of route of infection (intravenous or ...anti-HIV immune response during early infection could easily be ...
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REVIEW IMMUNOACTIVATION AND IMMUNOPATHOGENY DURING ACTIVE VISCERAL LEISHMANIASIS
... the immune system is highly ...poor immune response probably results from Leishmania antigen-engaged lymphocytes being trapped in the lymphoid ...high activation and deactivation processes are likely ...
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