Local renin angiotensin system
Local Fetal Lung Renin Angiotensin System
... Effect of PD-123319 treatment on left, right and total lung hypoplasia. Prenatal[r] ...
53
Regulation of the Renin-Angiotensin-Aldosterone System by Reactive Oxygen Species
... normoxia increased AGT protein expression without affecting the expression of the other RAAS components [23]. Surprisingly, in the adipose tissue, ROS seem to downregulate the expression of AGT. Indeed, during adipocyte ...
41
Characterization of the cardiac renin angiotensin system in oophorectomized and estrogen-replete mRen2.Lewis rats.
... the local cardiac renin-angiotensin system (RAS) is involved in the development and progression of cardiac hypertrophy, remodeling, and heart ...circulating angiotensin (Ang) II and ...
10
Role of renin-angiotensin system in development of heart failure induced by myocardial infarction in rats
... The local and/or circulating renin-angiotensin system (RAS) has long been considered responsible for car- diac remodeling and ventricular ...early angiotensin converting enzyme (ACE) ...
9
Functional evidence that the central renin-angiotensin system plays a role in the pressor response induced by central injection of carbachol
... 18. Predel HG, Duesing R, Baecker A, Kipnowiski J & Kramer HJ (1987). Com- bined treatment of severe essential hy- pertension with the new angiotensin con- verting enzyme inhibitor ramipril. Ameri- can Journal ...
4
Inappropriate activity of local renin-angiotensin-aldosterone system during high salt intake: impact on the cardio-renal axis
... Although there is a general agreement on the recommendation for reduced salt intake as a public health issue, the me- chanism by which high salt intake tri- ggers pathological effects on the cardio- -renal axis is not ...
9
The renin-angiotensin system is modulated by swimming training depending on the age of spontaneously hypertensive rats
... the local RAS from the systemic ...the local Ang II in the heart does not develop hypertrophy; it presents an increase of fibrosis and it develops hypertrophy only when an excess of cardiac Ang II enters the ...
7
Palmitoylethanolamide treatment reduces blood pressure in spontaneously hypertensive rats: involvement of cytochrome p450-derived eicosanoids and renin angiotensin system.
... producing local Ang II ...to local than circulating Ang II [34]. Therefore, local Ang II appears to be more important in the regulation of Ang II-induced ...
14
Renin angiotensin system and cardiac hypertrophy after sinoaortic denervation in rats
... Our results for left ventricle angiotensins show that SHR groups presented increased Ang II levels compared with WC. Classically, RAS is a systematic regulator in various biological activities. Ang II is the key effector ...
6
Effects of Exercise Training on Circulating and Skeletal Muscle Renin-Angiotensin System in Chronic Heart Failure Rats
... that local RAS becomes activated in tissues in CHF ...Circulating renin angiotensin system (RAS) in sedentary and exercise-trained Sham and CHF ...A, Angiotensin II; B, ...
11
EL SISTEMA RENINA−ANGIOTENSINA DESDE LA CIRCULACIÓN HASTA LA CÉLULA: IMPLICACIONES MÁS ALLÁ DE LA HIPERTENSIÓN / The renin−angiotensin system from circulation to the cell: implications beyond hypertension
... Las actividades fisiológicas del Sistema Renina-An- giotensina (SRA) siguen ampliándose mucho tiempo después de su descubrimiento en 1898, por el fisiólogo finlandés Robert Tigerstedt y su estudiante sueco Per Bergman, ...
7
UPDATES OF THE RENIN‐ANGIOTENSIN‐ALDOSTERON SYSTEM
... a local RAAS that acts independently on the systemic RAAS has been described ...of local and systemic angioten‑ sin peptides is dificult in terms of recent exper‑ ...Every system in the body contains ...
7
Local fetal lung renin angiotensin system as a target to treat congenital diaphragmatic hernia
... of renin-angiotensin system (RAS) during fetal lung ...of renin, angiotensin-con- verting enzyme, angiotensinogen, type 1 (AT 1 ) and type 2 (AT 2 ) receptors of angiotensin II ...
13
H(2)S inhibits hyperglycemia-induced intrarenal renin-angiotensin system activation via attenuation of reactive oxygen species generation.
... Oxidative stress may appear at a very early stage of DN. In cultured cell, the ROS production increased within an hour. Thus we speculate that high glucose stimulation shifts the balance between oxidative and reductive ...
13
In Vitro Regulation of Enzymes of the Renin-angiotensin-aldosterone System by Isoquercitrin, Phloridzin and their Long Chain Fatty Acid Derivatives
... The renin angiotensin aldosterone system (RAAS) is a physiological mechanism which regulates the blood pressure through the modulation of renal vasomotor function, salt and water balance ...[1]. ...
14
Role of the renin angiotensin system in blood pressure allostasis-induced by severe food restriction in female Fischer rats.
... Plasma Volume. Plasma volume was measured by the Evan’s blue dye technique as previously described 48 . In brief, after baseline blood collection, Evan’s blue dye (0.3 mg/ml) was infused into the venous catheter. Blood ...
15
Hyperkalemia and management of renin-angiotensin-aldosterone system inhibitors in chronic heart failure with reduced ejection fraction : a systematic review
... Objectives: Renin-angiotensin-aldosterone system inhibitors (RAASi) are the cornerstone of treatment of heart failure with reduced ejection fraction ...
25
Long-term effects of early overnutrition in the heart of male adult rats: role of the renin-angiotensin system.
... to angiotensin II and coronary endo- thelium-dependent vasodilatation to ...locally angiotensin II from angiotensinogen in the heart. Renin activity may be present in myocardial tissue of perfused ...
11
Reduced plasma levels of angiotensin-(1-7) and renin activity in preeclamptic patients are associated with the angiotensin I- converting enzyme deletiondeletion genotype
... The study protocol was approved by the Ethics Committee of the Federal University of Minas Gerais and written informed con- sent was obtained from all patients. We in- vestigated 20 hospitalized preeclamptic women and 20 ...
8
Alternative pathways for angiotensin II generation in the cardiovascular system
... The current awareness of the functional complexity of the multifaceted, multicomponent RAS has been reinforced by the identification of different proteases that can process both Ang I and Ang II to generate active ...
7