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Muscarinic receptors

ERK5 activation by Gq-coupled muscarinic receptors is independent of receptor internalization and β-arrestin recruitment.

ERK5 activation by Gq-coupled muscarinic receptors is independent of receptor internalization and β-arrestin recruitment.

... by muscarinic M1/M3 receptors does not seem to involve receptor internalization, which is one of the mechanisms for β- arrestin to initiate ...phosphorylation-deficient muscarinic Figure ...

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Constitutive overexpression of muscarinic receptors leads to vagal hyperreactivity.

Constitutive overexpression of muscarinic receptors leads to vagal hyperreactivity.

... in muscarinic receptor expression and acetylcholinesterase (AchE) activity have been observed in tissues from Sudden Infant Death Syndrome ...whether muscarinic receptor overexpression may be the underlying ...

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Development of fetal nicotine and muscarinic receptors in utero

Development of fetal nicotine and muscarinic receptors in utero

... cholinergic receptors are widespread in the peripheral and central systems, including smooth muscle and the epithelial lining of the cardiovascular, digestive, and urinary systems, as well as in the ...and ...

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Cigarette Smoke Disturbs the Survival of CD8+ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease.

Cigarette Smoke Disturbs the Survival of CD8+ Tc/Tregs Partially through Muscarinic Receptors-Dependent Mechanisms in Chronic Obstructive Pulmonary Disease.

... cholinergic receptors, including muscarinic acetylcholine receptors (mAChRs or MRs) and nicotinic acetylcholine receptors (nAChRs), and represent a cellular source of Ach ...

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Muscarinic receptors in amygdala control trace fear conditioning.

Muscarinic receptors in amygdala control trace fear conditioning.

... Intelligent behavior requires transient memory, which entails the ability to retain information over short time periods. A newly-emerging hypothesis posits that endogenous persistent firing (EPF) is the ...

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Acetylcholine produces contraction mediated by cyclooxigenase pathway in arterial vessels in the marine fish (Isacia conceptionis)

Acetylcholine produces contraction mediated by cyclooxigenase pathway in arterial vessels in the marine fish (Isacia conceptionis)

... Five muscarinic receptors in vascular smooth muscle have been identified by functional, pharmacological and molecular studies in a variety of fish and mammalian (agnathians, elasmobranch and teleosts) ...

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Effect of acetylcholine receptors on the pain-related electrical activities in the hippocampal CA3 region of morphine-addicted rats

Effect of acetylcholine receptors on the pain-related electrical activities in the hippocampal CA3 region of morphine-addicted rats

... by muscarinic receptor antagonists ...of receptors or ...of muscarinic receptors, by action of the toxin on central cholinergic neurons ...central muscarinic receptors mediate ...

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Trypanosoma cruzi infection induces up-regulation of cardiac muscarinic acetylcholine receptors in vivo and in vitro

Trypanosoma cruzi infection induces up-regulation of cardiac muscarinic acetylcholine receptors in vivo and in vitro

... The importance of the integrity of the cholinergic sys- tem in the development of Chagas disease myocardiopa- thy is still controversial. The development of alterations in mAChR expression and/or function and their role ...

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Arq. NeuroPsiquiatr.  vol.67 número3A

Arq. NeuroPsiquiatr. vol.67 número3A

... once the reason for that correlation is still unclear, we speculated that Chagas’ disease, even in early stages, can promote an imbalance between sympathetic and para- sympathetic systems and may promote an intense and ...

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Vascular function in arteries of intertidal fish

Vascular function in arteries of intertidal fish

... of muscarinic receptors with the production of vasoconstrictor prostanoids mediated by COX in Girella ...by muscarinic receptors in the vascular smooth muscle present in all the vessels ...

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Effects of the selective M1 muscarinic receptor antagonist dicyclomine on emotional memory

Effects of the selective M1 muscarinic receptor antagonist dicyclomine on emotional memory

... the muscarinic receptors would be primarily involved in its action on this type of ...of muscarinic receptors are known, named M1 to M4 (Waelbroeck et ...of muscarinic receptors ...

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HEART RATE RESPONSES TO A MUSCARINIC AGONIST IN RATS WITH EXPERIMENTALLY INDUCED ACUTE AND SUBACUTE CHAGASIC MYOCARDITIS

HEART RATE RESPONSES TO A MUSCARINIC AGONIST IN RATS WITH EXPERIMENTALLY INDUCED ACUTE AND SUBACUTE CHAGASIC MYOCARDITIS

... results of the present investigation showed that, the dose-response curves to arecoline of the infected animals studied during the acute and subacute stages of chagasic myocarditis, are not significantly different from ...

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Rev. bras. farmacogn.  vol.13 suppl.2

Rev. bras. farmacogn. vol.13 suppl.2

... cardiac muscarinic receptors participate in this ...cardiac muscarinic receptors10. The stimulation of these receptors induces intense bradycardia and hypotension, mainly due to the decrease ...

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Pharmacological study of the mechanisms involved in the vasodilator effect produced by the acute application of triiodothyronine to rat aortic rings

Pharmacological study of the mechanisms involved in the vasodilator effect produced by the acute application of triiodothyronine to rat aortic rings

... However, distilled water (vehicle of atropine) did not impede such vasorelaxation (Figure 2), suggesting the possible involvement of muscarinic receptors. Further experiments, which fall beyond the scope of ...

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Position of anticholinergic drugs in the treatment of childhood asthma

Position of anticholinergic drugs in the treatment of childhood asthma

... block muscarinic effect of acetylcholine on the receptors of postjunctional membranes and so inhibit the answer of the postganglionic parasympathetic ...M2 muscarinic receptors function occurs ...

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Exercício físico, receptores β-adrenérgicos e resposta vascular

Exercício físico, receptores β-adrenérgicos e resposta vascular

... induces vasoconstriction by activating α-adrenergic recep- tors present within vascular smooth muscle cells, whereas acetylcholine promotes vasodilation by activating mus- carinic receptors present within ...

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Organophosphate pesticides exposure bring out neurological symptoms in the children of agriculture workers in rural India: A community based cross-sectional study from Maharashtra.

Organophosphate pesticides exposure bring out neurological symptoms in the children of agriculture workers in rural India: A community based cross-sectional study from Maharashtra.

... both muscarinic and nicotinic observed in the present study could be because of the inhibition of red blood cells, acetyl cholinesterase, as well as plasma butyryl cholinesterase recorded in the study ...

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Transdermal delivery of scopolamine by natural submicron injectors: in-vivo study in pig.

Transdermal delivery of scopolamine by natural submicron injectors: in-vivo study in pig.

... the muscarinic receptor antagonist scopolamine, we found that the formulated injectors could penetrate porcine skin and immediately deliver this hydrophilic ...

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PDF EN Jornal Brasileiro de Pneumologia 2 15 english

PDF EN Jornal Brasileiro de Pneumologia 2 15 english

... estrogen receptors and progesterone receptors in cases of BML has been well documented and constitutes evidence that BML originates from uterine smooth ...

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Localization of NMDA receptors in the cerebral cortex: a schematic overview

Localization of NMDA receptors in the cerebral cortex: a schematic overview

... These receptors can monitor Glu re- lease by neighboring axon terminals (35,36) of thalamic (25) and corticocortical (70) ori- gin, as well as from axon collaterals of corti- cal Gluergic neurons (71), and ...

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