Mutational analysis of DNA
Mutational analysis of angiogenin gene in Parkinson's disease.
... total of 1498 study participants including 750 PD patients and 748 age/gender matched control subjects were included in this ...history of PD, 500 were sporadic late-onset PD and 200 were early-onset PD ...
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Mutational Analysis of Portuguese Families with Multiple Endocrine Neoplasia Type 1 Reveals Large Germline Deletions
... flanking DNA sequence repeats, which can give rise to a slipped-mispairing at the replication fork, during replication, followed by nucleotide excision as has been reported for the nt1656delC and nt735del4bp ...
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Mutational analysis of PPM1D in breast and ovarian cancer patients
... major DNA-repair ...loss of either gene is compatible with life, but simultaneous loss of both genes results in cell ...treatment of cancer (Hartwell et ...example of a successful ...
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Mutational analysis of circulating tumor cells from colorectal cancer patients and correlation with primary tumor tissue.
... source of tumor material from patients with ...is of great clini- cal importance regarding the increasing number of adjuvant treatment options for patients with metastatic carcinomas, in order to ...
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Low-density lipoprotein receptor mutational analysis in diagnosis of familial hypercholesterolemia
... spectrum of variants in the LDLR identified in patients with clinical familial hypercholestero- laemia is still increasing as novel variants keep on being ...awareness of the disorder and access to modern ...
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Human papillomavirus mutational insertion: specific marker of circulating tumor DNA in cervical cancer patients.
... serum of most patients diagnosed with invasive cervical carcinoma over stage Ib and that the amount of ctDNA reflected tumor ...[11] of positivity reported so far for c-HPV DNA. The practice ...
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Mutational analysis of KRAS and NRAS in metastatic colorectal cancer
... series of 241 mCRC samples wild-type for KRAS codons 12 and 13, we searched for mutations in the less frequently mutated KRAS mutational hotspots in exon 3 (codons 59/61) and 4 (codons 117/146) and in exon ...
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Mutational analysis gives insight into substrate preferences of a nucleotidyl cyclase from Mycobacterium avium.
... template DNA, 20 pmol of mutagenic primers (Fwd and Rvs), 1x concentration of the thermostable polymerase buffer, 25 mMdNTP’s and ...U of Pfu turbo in a total reaction volume of 50 m ...
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Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis.
... potential of becoming an important tool in clinical diagnosis and therapeutic decision-making in oncology owing to its enhanced sensitivity in DNA mutation detection, fast-turnaround of samples in ...
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Mutational robustness of gene regulatory networks.
... mutations of network structure. The results of our analysis provide several clues towards such ...aspects of why certain types of networks are more robust than ...expression of a ...
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Ultra-deep sequencing of mouse mitochondrial DNA: mutational patterns and their origins.
... mutations of mtDNA are implicated in the aging process, but there is no universally accepted method for their accurate ...liver of normally- and prematurely-aging ...levels of a truncated linear ...
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Molecular analysis of genetic diversity among vine accessions using DNA markers.
... purity of DNA obtained varied with respect to ...concentration of DNA was obtained, with a mean of ...limit of 1.6 to 2.0 according to Lahogue et al. (1998). Of the 119 ...
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Biological Evidence Management for DNA Analysis in Cases of Sexual Assault
... storage of the blood/DNA at room ...the DNA is concentrated ...amount of DNA in each hair (e.g., on average 200 ng of DNA compared to 10 ng in fallen hairs) depends on the ...
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Phylogenetic analysis of 16S mitochondrial DNA data in sloths and anteaters
... values of 100%) for the monophyly of the group constituted by Choloepus (Megalonychidae), Bradypus (Bradypodidae), Mylodon (Mylodontidae) and Nothrotheriops (Megatheriidae), simi- lar to the results ...
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DNA sequencing analysis of several G6PD variants previously defined by PCR-restriction enzyme analysis
... best of our knowledge the only mutations at nt 381-384 reported to date are the G6PD Vanua Lava 383 T ® C mutation and the silent polymorphisms at nt 381 C ® T and nt 384 C ® T (Beutler and Vulliamy 2002; Hamel et ...
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Morphologi cal analysis and DNA methylation in
... regions of Brazil, being, along with ...species of the genus Conyza as invasive in agricultural regions (Kissmann and Groth ...species of Conyza have a great capacity of adaptability, which ...
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Analysis of ancient DNA from coprolites: a perspective with random amplified polymorphic DNA-polymerase chain reaction approach
... volume of 50 µl, as follows: 10X PCR Buffer [200 mM Tris-HCl (pH ...µM of each dATP, dCTP, dGTP, dTTP, 125 ng/µl of oligonucleotides and 5 U of Taq ...Different DNA concentrations were ...
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Ultrastructural analysis and residual DNA evaluation of rabbit vein scaffold
... and analysis of residual DNA in scaf- fold models, produced with decellularized vena cava in an experimental model with ...residual DNA analysis: group 1 - control, consisting of ...
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Toward a DNA taxonomy of Alpine Rhithrogena (Ephemeroptera: Heptageniidae) using a mixed Yule-coalescent analysis of mitochondrial and nuclear DNA.
... sorting of ancestral polymorphism in PEPCK. This is based on the presence of shared genotypes among what were otherwise independent species by morphology and ...view of the extent of cryptic ...
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PRINCIPAL COMPONENT ANALYSIS WITH NEURAL NETWORK AND DNA SEQUENCE ANALYSIS
... Many papers have been written on the links between neural networks and principal components analysis and just as linear autoencoder implements a form of PCA, its has been shown that a si[r] ...
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