NF-kB
TNF- a inhibits SCF, ghrelin, and substance P expressions through the NF- kB pathway activation in interstitial cells of Cajal
... the NF-kB signaling ...the NF-kB signaling path- way in development of ulcerative ...the NF-kB signaling pathway may be a possible ther- apeutic strategy for treatment of ...
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HIPERAMONEMIA ATIVA HIF-1ɑ PELA VIA NF-kB: UM POSSÍVEL MECANISMO DE SARCOPENIA EM CIRROSE Rafaella Nascimento e Silva
... The present data shows that hyperammonemia is a normoxemic activator of HIF-1α signaling through NF-kB pathway. Hyperammonemia is an abnormality in cir- rhosis due to reduced urea synthesis because of ...
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Histone deacetylases and NF-kB signaling coordinate expression of CX3CL1 in epithelial cells in response to microbial challenge by suppressing miR-424 and miR-503.
... that NF-kB p50 does not directly interact with Sirt1 [33], we speculated that promoter recruitment of Sirt1 may depend on the binding of other co-regulators or transcription ...the NF-kB ...
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CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF- kB pathway
... Based on the above results, we focused on the nuclear factor-kB (NF-kB) pathway. As shown in Figure 4, phos- phorylated levels of IkBa and p65 were markedly down- regulated (Po0.01 or Po0.001) but ...
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Inducible HSP70 antagonizes IL-1β cytocidal effects through inhibiting NF-kB activation via destabilizing TAK1 in HeLa cells.
... and NF-kB signaling pathways ...inhibit NF-kB and MAPKs cascades via destabilizing TAK1 ...of NF-kB signaling was evaluated by detection of IkBa degradation, and the ...
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Captopril alleviates hypertension-induced renal damage, in flammation, and NF-kB activation
... the NF-kB complex is then freed to enter the nucleus where it can induce the expression of specific genes that have DNA- binding sites for NF-kB nearby ...of NF-kB, IkBa, and IKK, ...
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Avaliação dos níveis de interleucina8 e ativação do fator de transcrição nuclear NF–KB em pacientes portadores de síndromes mielodisplásicas
... O NF-kB encontra-se no citoplasma em sua forma inativa através da ligação com uma proteína inibitória ...complexo NF-kB/IkB impede a sua entrada no núcleo e sua liguação a regiões especificas ...
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Baicalein alleviates tubular-interstitial nephritis in vivo and in vitro by down-regulating NF-kB and MAPK pathways
... Primary human RPTECs were purchased from FMG- Bio (Sciencell, Shanghai, China), cultured in REBM/ REGM bullet kit (Biowhittaker Inc., USA) following the manufacturer’s instruction and confirmed by staining using ...
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Vitamin D prevents hypoxia/reoxygenation-induced blood-brain barrier disruption via vitamin D receptor-mediated NF-kB signaling pathways.
... induced translocation of the p65 subunit of NF-kB into the nucleus, which was blocked by P5P treatment. (B) Protein levels of phosphorylated IkBα in bEnd.3 cells as determined using Western blotting and ...
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Atividade inflamatória em mucosa de reservatório ileal na polipose adenomatosa familiar e retocolite ulcerativa inespecífica: avaliação da expressão de TNF-a e IL-1b, e da ativação NF- kB.
... Diversos mediadores inflamatórios são produ- zidos, a partir de estímulos intra-luminais, levando à li- beração de interleucinas, que estimulam a proliferação e ativação de linfócitos. Durante este processo, citocinas ...
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Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response.
... The initial events of mycobacterial infections are not clear. The first surface that the immobile bacterium will encounter after inhalation into the lungs would most likely be epithelial. Several groups have demonstrated ...
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Perfil da expressão imunoistoquímica de HER-2, NF-kB e IKK em câncer de colo uterino...
... of NF- κ B-p65 e NF- κ B-p50 before radiotherapy was found in respectively ...of NF- κ B-p65 and NF- κ B-p50 before radiotherapy was found in both ...of NF- κ B-p65 and NF- κ ...
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Inhibition of NF-kB 1 (NF-kBp50) by RNA interference in chicken macrophage HD11 cell line challenged with Salmonella enteritidis
... The NF-kB pathway plays an important role in regulating the immunity response in ...inhibit NF-kB 1 expression and to elucidate the role of NF-kB in the sig- nal transduction ...
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Papel da via de sinalização do NF-kB na inflamação do tecido adiposo subcutâneo de...
... do NF- ...do NF- κB, incluindo a via clássica de sinalização do NF- ...do NF- κB, IκB. A atividade do NF- κB no núcleo celular atinge um pico dentro de 30 minutos após estímulo da ...
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Crosstalk between NF-kB and PI3K-Akt-mTOR signalling in thyroid cancer: the pursuit of novel therapeutic options
... on NF-κB activation ...active NF-κB, which may be consistent with the decreased nuclear staining of p65 upon treatment with PI3K/mTOR ...on NF-κB ...of NF-κB activation status, needs further ...
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Estudo da expressão de MMP-2 e MMP-9 por fibroblastos gengivais de camundongos estimulados por NaF via NF-kB, p44/42, p38 e PI3K
... Figura 7 Produção de CCL3/MIP-1 fibroblastos gengivais estimulados por NaF (20 μg/mL) na ǂ nos sobrenadantes de ausência ou presença de LPS (10 μg/mL) no tempo de 6 horas.. 59.[r] ...
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O papel do fator nuclear kappa B (NF-kB) e do eixo IL-12/23-IFN-g na ativação do...
... o NF-κB, podem ser destacados: citocinas pró-inflamatórias, como o TNF-α e a IL-1, fatores ativadores de linfócitos T e B, LPS bacteriano, proteínas virais, fatores de crescimento e fatores indutores de estresse ...
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O estudo do NF-KB e da Survivina na progressão do Câncer Colorretal
... of NF- B and survivin in the progression of CRC, its relationship with molecular targets involved in cell survival [prohibitin, tumor necrosis factor (TNFR1), p53, catenina], invasion (metalloproteinases 2 and 9 - ...
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Análise do papel do H2O2 na regulação da activação do NF-KB
... pelo NF-κB, tem um papel de feedback negativo, permitindo uma rápida resposta on-off do NF-κB, com um carácter oscilatório da actividade nuclear do NF-κB; o IκBβ e o IκBε funcionam de modo a reduzir ...
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Receptor activator of NF-kB (RANK) expression in primary tumors associates with bone metastasis occurrence in breast cancer patients.
... In fact, based on the high constitutive RANK expression in breast cancer specimens and cell lines, recent data suggest that RANK expression status of cancer cells determines whether tumo[r] ...
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