Nitric Oxide Synthase Inhibitor
Lack of tolerance for the anti-dyskinetic effects of 7-nitroindazole, a neuronal nitric oxide synthase inhibitor, in rats
... neuronal nitric oxide synthase in vivo and reduces l-DOPA-induced dyskinesias in a rat model of ...neuronal nitric oxide synthase inhibitor does not develop over a ...
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Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis.
... decreased nitric oxide ...by nitric oxide synthase (NOS) is dependent in part on the relative bioavailability of arginine, the NOS sub- strate, and asymmetric dimethylarginine (ADMA), ...
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Effects of a neuronal nitric oxide synthase inhibitor on lipopolysaccharide-induced fever
... In the present experiment, the adminis- tration of 7-NI almost completely blocked the increase in body temperature induced by LPS. This finding could be explained by the same mechanisms that cause the decrease in ...
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Clinics vol.64 número5
... 71. Jiang JL, Jiang DJ, Tang YH, Li NS, Deng HW, Li YJ. Effect of simvastatin on endothelium-dependent vasorelaxation and endogenous nitric oxide synthase inhibitor. Acta Pharmacol Sin. ...
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Braz. J. Pharm. Sci. vol.48 número1
... of nitric oxide, as single or multiple dose regimens on dapsone-induced ...the nitric oxide synthase inhibitor L-NAME was investigated by treatment with multiple doses of 30 ...
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Genotoxic and anti-proliferative effects of aminoguanidine on gamma-irradiated MCF-7 breast cancer cells.
... of nitric oxide is studied as a relevant phenomenon in exposure to ioniz- ing ...local nitric oxide production in solid ...selective inhibitor of an isoform of nitric ...
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Reactive oxygen species in unstimulated hemocytes of the pacific oyster Crassostrea gigas: a mitochondrial involvement.
... NADPH-oxidase, nitric oxide synthase or myeloperoxidase, but from ...I inhibitor) had no effect on ROS ...III inhibitor) resulted in a dose-dependent ROS production decrease while an ...
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Alendronate induces gastric damage by reducing nitric oxide synthase expression and NOcGMPKATP signaling pathway
... Takeuchi, Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitor, Br. Kim, Effects of a nitric oxide donor and nitric oxide [r] ...
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Nitric oxide synthase and polycystic kidney disease
... endothelial nitric oxide synthase NOS3) is post-translationally lysine acetylated, leading to increased NO production in the ...deacetylase inhibitor, was found to inhibit cyst formation in ...
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Capric acid inhibits NO production and STAT3 activation during LPS-induced osteoclastogenesis.
... inducible nitric oxide synthase (iNOS) mRNA levels and nitric oxide (NO) production, whereas capric acid inhibited ...STAT3 inhibitor) inhibited ...
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Inducible nitric oxide synthase and tumor necrosis factor- α
... iNOS inhibitor N-(3-(amino- methyl) benzyl) acetamidine (1400 W; Alexis Biochemicals, Lausen, Switzerland), or 200 µg anti-mouse TNF-α ...Each inhibitor was administered ip in a vol- ume of 250 µL saline 1 ...
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Consequences of cerebroventricular insulin injection on renal sodium handling in rats: effect of inhibition of central nitric oxide synthase
... competitive inhibitor of nitric oxide (NO) synthase, results in marked insulin resistance, hyperglycemia, defective insulin secretion, and hyperten- ...
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ISSN 0100-879X BIOMEDICAL SCIENCES AND CLINICAL INVESTIGATION
... nNOS inhibitor could also result from inhibition of peripheral ...neuronal nitric oxide synthase (nNOS) immunostaining in the dorsal horn of the rat spinal cord after sciatic nerve transec- ...
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Neuronal and endothelial nitric oxide synthase gene knockout mice
... NOS inhibitor L-NA is simi- lar to that of eNOS mutant mice, and L-NA has no additional effects in the eNOS mu- tants, showing that the eNOS isoform is the only one involved in modulation of cardiac contractility ...
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Int. J. Cardiovasc. Sci. vol.30 número4
... 31. Jones SP, Greer JJM, van Haperen R, Duncker DJ, de Crom R, Lefer DJ. Endothelial nitric oxide synthase overexpression attenuates congestive heart failure in mice. Proc Natl Acad Sci USA. 2003; ...
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Nitric oxide synthase promotes distension-induced tracheal venular leukocyte adherence.
... endothelial nitric oxide synthase (eNOS, NOS-3) contributes to leukocyte recruit- ment to the airway when pro-inflammatory stimuli are imposed in ...cell-derived nitric oxide, the ...
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Hepatic inducible nitric oxide synthase expression increases upon exposure to hypergravity
... of nitric oxide (NO) from L-arginine and molecular oxygen has been proposed to mediate or modulate cellular damage in several organs, including the brain, kidneys, and liver ...NO synthase (NOS) ...
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Pré com nitrosil rutênio promove neuroproteção cerebral envolvendo proteína quinase em ratos in vivo
... Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3[r] ...
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Methylprednisolone stiffens aortas in lipopolysaccharide-induced chronic inflammation in rats.
... LPS, lipopolysaccharide; MP, methylprednisolone; LM, LPS groups treated with MP; iNOS, inducible nitric oxide synthase; AGEs, advanced glycation end products; RAGE, receptor for AGEs... [r] ...
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Endothelial nitric oxide synthase and superoxide mediate hemodynamic initiation of intracranial aneurysms.
... Previous studies have highlighted critical, yet contradictory roles for nitric oxide (NO) in regulating MMP induction in flow- dependent remodeling [13,14]. Inhibiting NO synthesis decreased MMPs and ...
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