Primary sequence
Wiggle-predicting functionally flexible regions from primary sequence.
... ent proteins. Here we consider five examples to make the point. First, molecular dynamic (MD) simulations of lysozyme show differences between the dynamics of substrate bound and free states. When lysozyme is in complex ...
17
Structural modeling of a novel CAPN5 mutation that causes uveitis and neovascular retinal detachment.
... closest sequence match) as a ...the primary sequence (Fig 2) showed the ADNIV Lys250Asn mutation was several residues away from the two known ADNIV mutations, the three-dimensional model reveals all ...
11
Mapping the small RNA content of simian immunodeficiency virions (SIV).
... Identification of vsRNAs in SIV virion preparations Our analysis showed that a small set of highly abundant vsRNAs can be isolated from SIV virion preparations. Evidence accumulates that RNA viruses can give rise to a ...
16
Whole-Chain Tick Saliva Proteins Presented on Hepatitis B Virus Capsid-Like Particles Induce High-Titered Antibodies with Neutralizing Potential.
... the primary sequence of wt ...extra sequence (ø) or the OspC binding regions (aa 48–67) of Salp15 or Iric-1 [10] was probed with the α-Salp/Iric Cys - CLP IS; DsbA-SaΔN59 protein served as positive ...
25
2010 Fritz et al FEBS J S100 review
... the primary sequence of S100 proteins to form b-rich oligomers and fibres, it is reasonable to envisage that factors such as an imbalance in metal homeostasis and anomalous protein–metal interactions, ...
13
Association of hepatitis C virus NS5B variants with resistance to new antiviral drugs among untreated patients
... The sequence fragment analysed in this study encompassed NS5B codons 228-336, including enzyme motifs B and ...the primary sequence of the palm domain because (i) this region has a polymorphism that ...
8
Structural analysis of mitochondrial mutations reveals a role for bigenomic protein interactions in human disease.
... Mitochondria are the energy producing organelles of the cell, and mutations within their genome can cause numerous and often severe human diseases. At the heart of every mitochondrion is a set of five large multi-protein ...
14
IMMUNOLOGICAL STUDY OF SPONGIFORM ENCEPHALOPATHIES
... basic primary sequence information, secondary structure information about the protein especially prion protein since the structure related information is more important to us since our major study of ...
4
Evidence for X-chromosomal schizophrenia associated with microRNA alterations.
... In summary, these studies represent the first statistically significant association between microRNA mutant alleles and schizophrenia. The absence of variants in 7,197 and additional control X-chromosomes and abnormal ...
11
On the relevance of sophisticated structural annotations for disulfide connectivity pattern prediction.
... the primary sequence with structural annotations, second they apply a binary classifier to each candidate pair of cysteines to predict disulfide bonding probabilities and finally, they use a maximum weight ...
14
Exploring the genes of yerba mate (Ilex paraguariensis A. St.-Hil.) by NGS and de novo transcriptome assembly.
... A. thaliana transcriptome as background. The assembled transcripts are categorized by cell component (Figure 2a) where an enrichment in organelle and cell structural components was observed, molecular function (Figure ...
16
THE THEORETICAL CONCEPTUAL FRAMEWORK WITH REFERENCE TO THE ROLE OF INSTITUTIONS IN THE PROCESS OF ACCESSION TO THE EU
... One of the primary competitive factors of a country is the state of institutions. EU membership requires substantial changes in the content and structure of the institutional framework of the acceding countries, ...
19
A collection of limits
... Since the sequence is strictly decreasing and it contains only positive terms, the sequence is bounded.. Using Weierstrass Theorem, it follows that the sequence is convergent..[r] ...
75
SOME CONSIDERATIONS ON THE DEMOGRAPHIC STRUCTURE OF MIGRANTS FROM BOTOSANI COUNTY
... Acest studiu își propune să analizeze particularitățile structurale ale emigranților din județul Botoșani, privind modelul de prezentare a structurii pe grupe de vârstă ș[r] ...
15
APPROACHES REGARDING DELIVERY OPERATIONS ACCOUNTING BY THE MANUFACTURER OF EXCISABLE MERCHANDISE
... Both the VAT and the excise duties are indirect taxes applicable on the movement of freight. The sequence of application is as follows: first the excise duties are calculated, then the amount of VAT from the sale ...
9
PROFILE OF GLAUCOMA IN A TERTIARY CARE CENTER OF KUMAON REGION, HALDWANI UTTARAKHAND
... of primary glaucoma identified included primary angle closure glaucoma 84(42%), primary open angle glaucoma 63(32%), glaucoma suspect 32(16%) and normal tension glaucoma ...was primary angle ...
7
Temporal Changes in BEXSERO® Antigen Sequence Type Associated with Genetic Lineages of Neisseria meningitidis over a 15-Year Period in Western Australia.
... four sub-capsular protein antigens supplemented with an outer membrane vesicle. Since the sub-capsular protein antigens are variably expressed and antigenically variable amongst meningococcal isolates, vaccine coverage ...
20
Development Of Method To Derive Variation Pattern In Neuraminidase Enzyme Of Influenza-A Virus And Predict The Most Probable Upcoming Subtype.
... The latest influenza outbreak has been recorded by WHO on 26 th April, 2016 in which a human was tested positive for H7N9, a similar case of influenza outbreak has been observed few days earlier by WHO in china on 23rd ...
6
A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi
... cDNAs are not derived from read-through transcripts from putative promoters far upstream. Together with other re- ports of transcribed but not translated sequences, the present work adds more evidences to this puzzling ...
5
Sequence to Medical Phenotypes: A Framework for Interpretation of Human Whole Genome DNA Sequence Data.
... genome sequence data is ...genome sequence data from twelve unrelated adults, and for disease gene discovery in one father-mother-child trio with apparently simplex con- genital ventricular ...
15