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randomized clinical trials

Clinical research in homeopathy: systematic reviews and randomized clinical trials

Clinical research in homeopathy: systematic reviews and randomized clinical trials

... and clinical efficacy, for which various grading systems were ...of randomized clinical trials (RCT) and individual RCT considered as the highest level ...the clinical effects of ...

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Systematic review and meta-analysis of randomized clinical trials in the treatment of human brucellosis.

Systematic review and meta-analysis of randomized clinical trials in the treatment of human brucellosis.

... were randomized clinical trials in patients presenting acute ...Controlled Trials (CENTRAL) was conducted for studies related to the term ‘‘brucellosis’’, which resulted in the identification ...

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Effectiveness of ozone therapy compared to other therapies for low back pain : a systematic review with meta-analysis of randomized clinical trials

Effectiveness of ozone therapy compared to other therapies for low back pain : a systematic review with meta-analysis of randomized clinical trials

... Method: We used randomized clinical trials to compare the effectiveness of ozone and other therapies for lumbar pain relief in adults (Prospero: CRD42018090807). Two independent reviewers searched ...

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Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials.

... of randomized clinical trials (RCTs) based on archived pro- tocols approved by six research ethics committees between 13 January 2000 and 25 November ...(62.0%) trials were ...

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Use of dexamethasone intravitreal implant for the treatment of diabetic macular edema : analysis of randomized clinical trials

Use of dexamethasone intravitreal implant for the treatment of diabetic macular edema : analysis of randomized clinical trials

... best clinical evidence concerning the use of dexamethasone intravitreal implant in diabetic macular edema ...randomised clinical trials (RCTs) searched through several ...

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Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials.

Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials.

... eight trials included in the funnel ...the trials claimed a positive effect of Huperzine A, we still suspected there might be some ‘negative’ studies ...of clinical trials and/or publication ...

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Drug-eluting stents Versus Coronary Artery Bypass Grafting in Multivessel Disease and Left Main Obstruction: Meta-analysis of Randomized Clinical Trials

Drug-eluting stents Versus Coronary Artery Bypass Grafting in Multivessel Disease and Left Main Obstruction: Meta-analysis of Randomized Clinical Trials

... of Randomized Comparison of Bypass Surgery versus Angioplasty Using Sirolimus‑Eluting Stent in Patients with Left Main Coronary Artery Disease; EXCEL: Coronary Artery Bypass Surgery for Effectiveness of Left Main ...

11

Lumiracoxib for acute postoperative dental pain: a systematic review of randomized clinical trials

Lumiracoxib for acute postoperative dental pain: a systematic review of randomized clinical trials

... onstrated, this study was included in the present review. Regarding the results from continuous variables, the overall efect measured only by comparing the means ater the treatment may not be representative of the ...

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Outcome measures for disease-modifying therapies in relapsing multiple sclerosis randomized clinical trials

Outcome measures for disease-modifying therapies in relapsing multiple sclerosis randomized clinical trials

... III clinical trials, the most recent of which was published in ...outstanding clinical perspective, but had a major limitation in the lack of a comprehensive search and systematic data sum- ...of ...

7

Characteristics of randomized controlled trials designed for elderly: a systematic review.

Characteristics of randomized controlled trials designed for elderly: a systematic review.

... controlled trials (RCT) are the hallmark of evidence-based medicine and form the basis of treatment ...in randomized clinical ...Therefore, clinical trials enrolling older patients may ...

8

Physical therapy in patients with Alzheimer’s disease: a systematic review of randomized controlled clinical trials

Physical therapy in patients with Alzheimer’s disease: a systematic review of randomized controlled clinical trials

... ABSTRACT | The objective of this study is to evaluate the effects of physical therapy on the cognitive and functional capacity of patients with Alzheimer’s Disease (AD). This is a systematic review of randomized ...

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Ongoing Clinical Trials with Monoclonal Antibodies in Schizophrenia

Ongoing Clinical Trials with Monoclonal Antibodies in Schizophrenia

... So far, experts have found that schizophrenic patients have alterations in the number of immune cell numbers, inflammatory markers and antibody titres in the blood and cerebrospinal fluid. (Kirkpatrick and Miller 2013) ...

25

Developing Clinical Trials in The Portuguese Family Medicine

Developing Clinical Trials in The Portuguese Family Medicine

... t is important to develop a national program for research in health. The European scientific panorama in the health field is extremely vast, taking a leading role in the investment in research and development, ...

68

Treatment of Non-neurogenic Overactive Bladder with OnabotulinumtoxinA: Systematic Review and Meta-analysis of Prospective, Randomized, Placebo-controlled Clinical Trials

Treatment of Non-neurogenic Overactive Bladder with OnabotulinumtoxinA: Systematic Review and Meta-analysis of Prospective, Randomized, Placebo-controlled Clinical Trials

... of randomized placebo-controlled trials that studied non-neurogenic overactive bladder patients who were treated with 100 units of onabotulinumtoxinA or ...the clinical effectiveness with regard to ...

7

Whole animal experiments should be more like human randomized controlled trials.

Whole animal experiments should be more like human randomized controlled trials.

... allocation, and none reported methods to determine sample size [6]. Similar concerns about underreporting crucial aspects of study design and conduct have been raised by a recent (June 2012) U.S. National Institute of ...

6

Assessing Risk of Bias in Randomized Controlled Trials for Autism Spectrum Disorder

Assessing Risk of Bias in Randomized Controlled Trials for Autism Spectrum Disorder

... 94 clinical trials within 10 systematic reviews), SEs were computed by a sandwich estimator and a chi-square test of the model fit which took into account the non-independence of ...

6

Biomedical information extraction for matching patients to clinical trials

Biomedical information extraction for matching patients to clinical trials

... the trials normally are relevant to oncology ...gave trials that contain them an increase in score, which will be added to the scoring of the searching ...

118

Curricular training report: clinical trials coordination in neurology

Curricular training report: clinical trials coordination in neurology

... Discovering and developing new drugs is a complex and long-term process that consists of several stages and involves various players (8,10). The pharmaceutical R&D (Figure 3) begins with drug discovery followed by ...

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Transparency and accuracy in funding investigator-initiated clinical trials

Transparency and accuracy in funding investigator-initiated clinical trials

... non-commercial clinical trials (ie, IICTs), involving Portuguese institutions recruiting ...four clinical trial registries, clinical trials registries (CTRs) (EU Clinical ...

8

Training report in clinical trials coordination at Blueclinical, LTD

Training report in clinical trials coordination at Blueclinical, LTD

... First of all, after a new proposal to a new study is received, it is necessary to identify who is/are the physician(s) from the site that can have interest in the study. This new proposal can be received from three ...

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