Rat model
Alloxan-induced diabetes delays repair in a rat model of closed tibial fracture
... Consistent with previous clinical and experimental data (5-13), we found that diabetes delayed fracture healing in a rat model of closed fracture. This delay was initiated at early stages of healing, ...
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Efficacy and toxicity evaluation of celastrol in adjuvant-induced arthritis rat model
... AIA rat model of ...the rat group treated with a dosage of ...arthritic rat group and to the rat group treated with a dosage of 1 μg/g of ...
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Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome
... Quercetin shows protective effects against hepatopulmonary syndrome (HPS), as demonstrated in a rat model. However, whether these effects involve pulmonary vascular angiogenesis in HPS remains unclear. ...
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Transplantation of rat-derived microglial cells promotes functional recovery in a rat model of spinal cord injury
... inflammatory mediators (such as IL-beta, TNF-alpha) in response to infectious and traumatic stimuli. Microglia modulate both the activation and down-regulation of an immune response in the CNS (6,9). In addition, ...
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Relaxin Treatment in an Ang-II-Based Transgenic Preeclamptic-Rat Model.
... transgenic rat model of preeclampsia, where the phenotype is induced by angiotensin (Ang)-II production in mid ...Ang-II-based model of pre- eclampsia, we could not show a salubrious effect on ...
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Melissa officinalis extract inhibits laser-induced choroidal neovascularization in a rat model.
... CNV rat model does not perfectly mimic exudative AMD in ...a model of acute injury and inflammation, rather than one of long standing senile degeneration and chronic inflammation ...
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Establishment of a novel rat model of severe acute cholangitis
... animal model provides an important foundation and condition for experimental studies on ...animal model for ACST is a rat model established by the complete obstruction of the biliary tract and ...
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Tadalafil attenuates graft arteriosclerosis of aortic transplant in a rat model
... Activation of NO‐cGMP pathway via inhibiting PDE activity could cause smooth muscle relaxation and VSMC proliferation inhibition. Thus, NO enhancing therapies are an attractive area to explore. To date, no studies have ...
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CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension.
... the rat increases intraocular ...a rat model of ocular hypertension decreases intraocular pressure, prevents retinal neurodegeneration, and preserves visual ...
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Alloxan-induced diabetes delays repair in a rat model of closed tibial fracture
... Consistent with previous clinical and experimental data (5-13), we found that diabetes delayed fracture healing in a rat model of closed fracture. This delay was initiated at early stages of healing, ...
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Reversal learning and associative memory impairments in a BACHD rat model for Huntington disease.
... tgHD rat model of HD that carry the human mutation with 51 CAG repeats [17], Fielding and colleagues [18] have not found significant impairment in object recognition, set shifting, and operant tests, ...
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Exercises in hot and humid environment caused liver injury in a rat model.
... our rat model study, we induced heat strokes by forced extreme exercises in a hot and humid environment and observed changes of blood biochemistry, organ histology, inflammatory responses as well as ...
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Therapeutic effect of frankincense in a rat model of Alzheimer’s disease
... Neuro-inflammation that is associated with AD contributes to AD pathogenesis (Heppner et al., 2015). In the i.c.v STZ model of AD, there is also a neuro- inflammatory condition (Nazem et al., 2015). In this ...
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Development of a subcutaneous endometriosis rat model
... The relative wet weight of the endometrioma in the three medroxyprogesterone acetate groups (0.5mg/kg, 2mg/kg and 5mg/ kg) decreased signiicantly in relation to the control (p=0.0069), but no difference was observed ...
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Molecular profiling of the lateral habenula in a rat model of depression.
... Genes that were significantly altered by CMS and antidepres- sant treatment were functionally classified into cellular pathways using the Protein ANalysis THrough Evolutionary Relationships (PANTHER, www.pantherdb.org) ...
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Abnormal Motor Activity and Thermoregulation in a Schizophrenia Rat Model for Translational Science.
... In conclusion, the data give strong argument to support the use of telemetry as a complemen- tary tool to evaluate BT and motor activity changes of rats in freely moving condition. These data show that the new substrain ...
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A sulfated fraction from seaweed gracilaria birdiae prevents naproxeninduced damage in rats
... NSAIDs, such as naproxen, are the most widely used pharmacological agents for the treatment of pain and inflammation [21]. However, 15% –30% of the patients who receive these drugs develop gastrointestinal ulcers [22]. ...
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Arq. Bras. Oftalmol. vol.77 número4
... Purpose: To compare the effects of bevacizumab applied either subconjunctivally or topically, in a rat model of corneal neovascularization induced by alkali burn. Methods: The right corneas of 24 ...
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